| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mebendazole perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mebendazole_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.111033 |
| CALR | calreticulin | 0.0880669 |
| TMSB4X | thymosin beta 4, X-linked | 0.0745111 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0667999 |
| PLEC | plectin | 0.065576 |
| BCL2L1 | BCL2-like 1 | 0.0613211 |
| MKI67 | marker of proliferation Ki-67 | 0.0610353 |
| HLA-C | major histocompatibility complex, class I, C | 0.0538081 |
| PTMA | prothymosin, alpha | 0.0526019 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0515386 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0444234 |
| HYOU1 | hypoxia up-regulated 1 | 0.0440914 |
| RPN1 | ribophorin I | 0.0435256 |
| AHNAK | AHNAK nucleoprotein | 0.0434381 |
| KRT8 | keratin 8, type II | 0.0413346 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0392343 |
| RPL7A | ribosomal protein L7a | 0.0375378 |
| SEPTIN9 | septin 9 | 0.0369209 |
| ANLN | anillin, actin binding protein | 0.0360979 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0356167 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0354757 |
| H1-0 | H1.0 linker histone | 0.0352965 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0345848 |
| HMGB2 | high mobility group box 2 | 0.0339727 |
| ACTG1 | actin gamma 1 | 0.0336413 |
| RAD21 | RAD21 homolog (S. pombe) | 0.032785 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0327765 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0324559 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0318377 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0308869 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0297645 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0295551 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0295014 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.0287493 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0286544 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0279907 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0263418 |
| HLA-B | major histocompatibility complex, class I, B | 0.0262579 |
| CENPE | centromere protein E, 312kDa | 0.0260173 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0259614 |
| TPX2 | TPX2, microtubule-associated | 0.0258386 |
| SMAD3 | SMAD family member 3 | 0.0254139 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0247629 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.0245825 |
| ACTN4 | actinin, alpha 4 | 0.0245492 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0242557 |
| FLNA | filamin A, alpha | 0.0239347 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0238415 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0235303 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0234113 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0232735 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0232659 |
| B2M | beta-2-microglobulin | 0.0231108 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0230976 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0227461 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0227175 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0226634 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0225894 |
| CENPF | centromere protein F, 350/400kDa | 0.0225446 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0219011 |
| RPS21 | ribosomal protein S21 | 0.0218542 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0217477 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0215876 |
| LAMB3 | laminin, beta 3 | 0.0212624 |
| DIAPH3 | diaphanous-related formin 3 | 0.0209683 |
| KIF4A | kinesin family member 4A | 0.0209368 |
| RPL4 | ribosomal protein L4 | 0.0204947 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0203477 |
| PRSS3 | protease, serine, 3 | 0.0202699 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 0.0201857 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.020184 |
| KRT18 | keratin 18, type I | 0.0200025 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0199926 |
| SDC4 | syndecan 4 | 0.0197914 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0196868 |
| PRPF6 | pre-mRNA processing factor 6 | 0.0196143 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0195933 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0193557 |
| RPS9 | ribosomal protein S9 | 0.0192165 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0189421 |
| STMN1 | stathmin 1 | 0.0187385 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.0187235 |
| CEP70 | centrosomal protein 70kDa | 0.0187098 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 0.0187037 |
| RBBP6 | retinoblastoma binding protein 6 | 0.018611 |
| EPHA2 | EPH receptor A2 | 0.0185673 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0185293 |
| SPAG9 | sperm associated antigen 9 | 0.0183573 |
| DUSP4 | dual specificity phosphatase 4 | 0.0183211 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0182659 |
| CCDC47 | coiled-coil domain containing 47 | 0.017602 |
| ASPH | aspartate beta-hydroxylase | 0.017585 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0175506 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.0175435 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0175229 |
| EPCAM | epithelial cell adhesion molecule | 0.0174192 |
| SPAG5 | sperm associated antigen 5 | 0.017398 |
| CCNL1 | cyclin L1 | 0.0171822 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0171661 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0171472 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EMP1 | epithelial membrane protein 1 | -0.156607 |
| NDRG1 | N-myc downstream regulated 1 | -0.140272 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.135349 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.128293 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.119193 |
| NPSR1 | neuropeptide S receptor 1 | -0.116819 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0939907 |
| RPS6 | ribosomal protein S6 | -0.088921 |
| FTL | ferritin, light polypeptide | -0.0859325 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0824074 |
| ANXA1 | annexin A1 | -0.0817862 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0803327 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0770371 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0755361 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0734085 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0695081 |
| EZR | ezrin | -0.0680542 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0669008 |
| ENO1 | enolase 1, (alpha) | -0.0656703 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0651658 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0647916 |
| WDR45B | WD repeat domain 45B | -0.0638092 |
| PKM | pyruvate kinase, muscle | -0.0635776 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0633613 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0632989 |
| AGR2 | anterior gradient 2 | -0.062694 |
| LMO7 | LIM domain 7 | -0.060205 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0596849 |
| DSTN | destrin (actin depolymerizing factor) | -0.0594674 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.059136 |
| CDK6 | cyclin-dependent kinase 6 | -0.058228 |
| AGR3 | anterior gradient 3 | -0.0553573 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0538531 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.053023 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0526303 |
| EHBP1 | EH domain binding protein 1 | -0.0509333 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0505607 |
| GOLGA4 | golgin A4 | -0.0486095 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0475618 |
| VEGFA | vascular endothelial growth factor A | -0.0472294 |
| TMEM123 | transmembrane protein 123 | -0.0468808 |
| LDHA | lactate dehydrogenase A | -0.046879 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0466555 |
| AREG | amphiregulin | -0.0455152 |
| RPS25 | ribosomal protein S25 | -0.0454866 |
| ZNF292 | zinc finger protein 292 | -0.0436327 |
| GRB10 | growth factor receptor-bound protein 10 | -0.043476 |
| PGK1 | phosphoglycerate kinase 1 | -0.0433 |
| COBL | cordon-bleu WH2 repeat protein | -0.0422828 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0421291 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0419308 |
| LCN2 | lipocalin 2 | -0.0418512 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0416454 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0414267 |
| ATXN1 | ataxin 1 | -0.0414118 |
| RBM39 | RNA binding motif protein 39 | -0.0403792 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0402357 |
| DIAPH2 | diaphanous-related formin 2 | -0.0400598 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0399656 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0390593 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0389783 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0386492 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0384489 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0382488 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0381686 |
| HMGA1 | high mobility group AT-hook 1 | -0.0379538 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0375865 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0372191 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.036348 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0359484 |
| RPS16 | ribosomal protein S16 | -0.0357718 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0349432 |
| CCNY | cyclin Y | -0.0346693 |
| TPD52 | tumor protein D52 | -0.0341222 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.03351 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0326835 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0326797 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0325034 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0323827 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0320353 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0317779 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.031689 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0315786 |
| ITGA6 | integrin, alpha 6 | -0.0315395 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0314606 |
| AHR | aryl hydrocarbon receptor | -0.0313977 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0313583 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0313209 |
| LIMA1 | LIM domain and actin binding 1 | -0.031218 |
| AUTS2 | autism susceptibility candidate 2 | -0.0311031 |
| VMP1 | vacuole membrane protein 1 | -0.0309788 |
| SBF2 | SET binding factor 2 | -0.0309518 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0306701 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0305298 |
| POTEF | POTE ankyrin domain family, member F | -0.0304857 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0304758 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0302757 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.030089 |
| TCF12 | transcription factor 12 | -0.0300763 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0299092 |
