| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mebendazole perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mebendazole_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.315108 |
| PTMA | prothymosin, alpha | 0.29304 |
| TMSB4X | thymosin beta 4, X-linked | 0.218724 |
| TMSB10 | thymosin beta 10 | 0.120331 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.116014 |
| ACTG1 | actin gamma 1 | 0.103784 |
| CALR | calreticulin | 0.095863 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0706938 |
| MKI67 | marker of proliferation Ki-67 | 0.0605966 |
| RAI1 | retinoic acid induced 1 | 0.0597518 |
| CENPF | centromere protein F, 350/400kDa | 0.0547606 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0540244 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0533759 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0513725 |
| RPL7A | ribosomal protein L7a | 0.0504309 |
| RPL23 | ribosomal protein L23 | 0.0492467 |
| CAPRIN2 | caprin family member 2 | 0.0481298 |
| EZR | ezrin | 0.0462067 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0443282 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0425099 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0421921 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0410704 |
| YBX1 | Y box binding protein 1 | 0.0407425 |
| AHNAK | AHNAK nucleoprotein | 0.0400953 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0399696 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0397696 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0388258 |
| MT2A | metallothionein 2A | 0.0381425 |
| LOXL2 | lysyl oxidase-like 2 | 0.036434 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0361546 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0356926 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0352089 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0342807 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0332452 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.033015 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0322726 |
| RBM25 | RNA binding motif protein 25 | 0.0313954 |
| RPL3 | ribosomal protein L3 | 0.0309595 |
| SMAD3 | SMAD family member 3 | 0.0305581 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0303895 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0301163 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.029906 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0296704 |
| FNIP1 | folliculin interacting protein 1 | 0.0291179 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0283629 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0274266 |
| YEATS2 | YEATS domain containing 2 | 0.0274204 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0266055 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0261549 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0258606 |
| TPR | translocated promoter region, nuclear basket protein | 0.0256669 |
| HSPA8 | heat shock 70kDa protein 8 | 0.024994 |
| RPL12 | ribosomal protein L12 | 0.0247566 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0244587 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0243961 |
| ZNF160 | zinc finger protein 160 | 0.024203 |
| SLK | STE20-like kinase | 0.024202 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0242006 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0238139 |
| PCDH1 | protocadherin 1 | 0.023809 |
| RPL19 | ribosomal protein L19 | 0.0238034 |
| PNN | pinin, desmosome associated protein | 0.023709 |
| TPM3 | tropomyosin 3 | 0.0236727 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0235416 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0233841 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0231032 |
| SET | SET nuclear proto-oncogene | 0.0229639 |
| FOSL1 | FOS-like antigen 1 | 0.0226328 |
| PLEC | plectin | 0.0226118 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0225834 |
| RPL4 | ribosomal protein L4 | 0.0224736 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0223324 |
| VEGFA | vascular endothelial growth factor A | 0.0222534 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0220928 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0220172 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0219974 |
| PGK1 | phosphoglycerate kinase 1 | 0.0219593 |
| RPN1 | ribophorin I | 0.0214032 |
| HDGF | hepatoma-derived growth factor | 0.0211257 |
| ADM | adrenomedullin | 0.0209537 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0208723 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0208088 |
| SPAG9 | sperm associated antigen 9 | 0.0207044 |
| RPS19 | ribosomal protein S19 | 0.0206747 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0204222 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.020271 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0201753 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0201203 |
| CEP250 | centrosomal protein 250kDa | 0.0200416 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0200281 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0200195 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0199965 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0198613 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0197426 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0196826 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.019537 |
| ITGB4 | integrin, beta 4 | 0.0194032 |
| EPHA2 | EPH receptor A2 | 0.019382 |
| PLAU | plasminogen activator, urokinase | 0.0191187 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0190843 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | -0.134325 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0945798 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0752321 |
| TXNRD1 | thioredoxin reductase 1 | -0.0739395 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0736127 |
| CD44 | CD44 molecule (Indian blood group) | -0.0693092 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0631884 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0617714 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0609177 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0548417 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0515764 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0445869 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0428782 |
| MT1X | metallothionein 1X | -0.0418124 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0409501 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0394586 |
| RPL35A | ribosomal protein L35a | -0.0393829 |
| CADM2 | cell adhesion molecule 2 | -0.0388342 |
| RPS24 | ribosomal protein S24 | -0.0387467 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0384559 |
| DST | dystonin | -0.0383697 |
| RPL36A | ribosomal protein L36a | -0.0365884 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0364222 |
| RPS13 | ribosomal protein S13 | -0.0349573 |
| RPL37 | ribosomal protein L37 | -0.0348404 |
| RPLP2 | ribosomal protein, large, P2 | -0.0342018 |
| HLA-B | major histocompatibility complex, class I, B | -0.0328914 |
| RPL34 | ribosomal protein L34 | -0.0326337 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0319542 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0317504 |
| SP100 | SP100 nuclear antigen | -0.0316081 |
| EHBP1 | EH domain binding protein 1 | -0.0314333 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0307978 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.030738 |
| RPS25 | ribosomal protein S25 | -0.0304068 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0289571 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0288287 |
| RPS12 | ribosomal protein S12 | -0.0287227 |
| EGR1 | early growth response 1 | -0.0281623 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0277587 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0267899 |
| RPLP0 | ribosomal protein, large, P0 | -0.0267471 |
| RPS6 | ribosomal protein S6 | -0.0265829 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.025169 |
| RPLP1 | ribosomal protein, large, P1 | -0.0250083 |
| RPL31 | ribosomal protein L31 | -0.0249394 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0248879 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0248735 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0248087 |
| RPS8 | ribosomal protein S8 | -0.0247087 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0245327 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0245224 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0244967 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.024349 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0241999 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0240543 |
| RPS23 | ribosomal protein S23 | -0.0239822 |
| IPO7 | importin 7 | -0.0235068 |
| FBXO11 | F-box protein 11 | -0.0234536 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0233653 |
| RPL38 | ribosomal protein L38 | -0.0233632 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0228889 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0225106 |
| RPL27A | ribosomal protein L27a | -0.0224904 |
| JMJD1C | jumonji domain containing 1C | -0.0222845 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0222165 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0219971 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0219911 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0219595 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0219079 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0216439 |
| RIGI | RNA sensor RIG-I | -0.0207011 |
| NEK10 | NIMA-related kinase 10 | -0.0206177 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0205454 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0205424 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0204058 |
| MT1E | metallothionein 1E | -0.0204051 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0202869 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0202721 |
| PLSCR1 | phospholipid scramblase 1 | -0.0201595 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.020142 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0201245 |
| INTS6 | integrator complex subunit 6 | -0.0201209 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0199435 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0196703 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0196475 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0195952 |
| PYGL | phosphorylase, glycogen, liver | -0.0193117 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0191713 |
| USP34 | ubiquitin specific peptidase 34 | -0.0191029 |
| RPS27A | ribosomal protein S27a | -0.0190776 |
| EREG | epiregulin | -0.0189349 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0188641 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0188371 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0188072 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.018686 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0184944 |
| RPS27 | ribosomal protein S27 | -0.0181915 |
| TGM2 | transglutaminase 2 | -0.0181824 |
| NF1 | neurofibromin 1 | -0.0180415 |
