| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mebendazole perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mebendazole_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.173201 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.121131 |
| MKI67 | marker of proliferation Ki-67 | 0.107945 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0890156 |
| ACTG1 | actin gamma 1 | 0.0809477 |
| TPM3 | tropomyosin 3 | 0.069656 |
| TMSB10 | thymosin beta 10 | 0.0683351 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0676418 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0668295 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.064791 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0586335 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0567815 |
| RPL7A | ribosomal protein L7a | 0.0564595 |
| RRM2 | ribonucleotide reductase M2 | 0.0507433 |
| RBM25 | RNA binding motif protein 25 | 0.0507198 |
| RPL19 | ribosomal protein L19 | 0.0492104 |
| RPS3 | ribosomal protein S3 | 0.0490351 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0465598 |
| YBX1 | Y box binding protein 1 | 0.0458487 |
| KRT18 | keratin 18, type I | 0.0455167 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0444219 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0441144 |
| RPL23 | ribosomal protein L23 | 0.0422356 |
| RPL3 | ribosomal protein L3 | 0.0412828 |
| CALR | calreticulin | 0.0404415 |
| RPL12 | ribosomal protein L12 | 0.0398891 |
| PLEC | plectin | 0.0397483 |
| STMN1 | stathmin 1 | 0.0397239 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0394858 |
| RPL4 | ribosomal protein L4 | 0.0392322 |
| RPS19 | ribosomal protein S19 | 0.0387316 |
| CEP250 | centrosomal protein 250kDa | 0.0379378 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0378233 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0372459 |
| YBX3 | Y box binding protein 3 | 0.0371128 |
| TPM2 | tropomyosin 2 (beta) | 0.0369658 |
| SMAD3 | SMAD family member 3 | 0.0369243 |
| SMC4 | structural maintenance of chromosomes 4 | 0.036317 |
| RPL26 | ribosomal protein L26 | 0.0361404 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0354094 |
| RPS17 | ribosomal protein S17 | 0.0348611 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0346863 |
| RPL37A | ribosomal protein L37a | 0.0345023 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0344077 |
| RPL36 | ribosomal protein L36 | 0.0341732 |
| RPL13A | ribosomal protein L13a | 0.0336342 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0332691 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0327619 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0320072 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0312468 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0309058 |
| SPAG5 | sperm associated antigen 5 | 0.0307438 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0306683 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0300323 |
| FLNA | filamin A, alpha | 0.0299933 |
| GPX4 | glutathione peroxidase 4 | 0.0298714 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0298617 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0297327 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0295962 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0295085 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0294185 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0293467 |
| SET | SET nuclear proto-oncogene | 0.0292475 |
| PNN | pinin, desmosome associated protein | 0.029127 |
| RPN1 | ribophorin I | 0.0285717 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0281399 |
| CENPF | centromere protein F, 350/400kDa | 0.0275723 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0271025 |
| RPL11 | ribosomal protein L11 | 0.0267609 |
| MAGEA4 | melanoma antigen family A4 | 0.0256361 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0253028 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0248342 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0245294 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0244232 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0242035 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.0241146 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0240879 |
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.0236961 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0236257 |
| TPR | translocated promoter region, nuclear basket protein | 0.023467 |
| CMIP | c-Maf inducing protein | 0.0234144 |
| ACTN1 | actinin, alpha 1 | 0.0234023 |
| ANKRD12 | ankyrin repeat domain 12 | 0.023144 |
| TMSB4X | thymosin beta 4, X-linked | 0.0231171 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.023047 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0226288 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0222628 |
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | 0.0222482 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0221466 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0217899 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.021643 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0216326 |
| HLA-C | major histocompatibility complex, class I, C | 0.0215137 |
| HDGF | hepatoma-derived growth factor | 0.02129 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0212374 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.0211691 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0210811 |
| DDX23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 | 0.0210376 |
| CEP192 | centrosomal protein 192kDa | 0.0209198 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.020671 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165026 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.119826 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0970775 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0949814 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0815096 |
| TXNRD1 | thioredoxin reductase 1 | -0.0776268 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.076386 |
| JMJD1C | jumonji domain containing 1C | -0.0670056 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0667139 |
| RBM39 | RNA binding motif protein 39 | -0.0654493 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0633469 |
| PFN1 | profilin 1 | -0.0625296 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0604648 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0598834 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0568056 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0567719 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0562489 |
| VMP1 | vacuole membrane protein 1 | -0.054246 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0540324 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0539513 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0531369 |
| NF1 | neurofibromin 1 | -0.0528918 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0509678 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0494766 |
| USP34 | ubiquitin specific peptidase 34 | -0.0490454 |
| RPLP0 | ribosomal protein, large, P0 | -0.0490068 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0489728 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0483405 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0461836 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0449068 |
| BBX | bobby sox homolog (Drosophila) | -0.0437694 |
| SBF2 | SET binding factor 2 | -0.0432714 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0427095 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0411996 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0408885 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0401087 |
| PCBP2 | poly(rC) binding protein 2 | -0.0397434 |
| GPHN | gephyrin | -0.0383891 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0381744 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0378244 |
| TUBA1B | tubulin, alpha 1b | -0.0374233 |
| PHF20 | PHD finger protein 20 | -0.0372642 |
| FBXO11 | F-box protein 11 | -0.0372239 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0372025 |
| TFG | TRK-fused gene | -0.0370683 |
| CD2AP | CD2-associated protein | -0.0370463 |
| XPO1 | exportin 1 | -0.036738 |
| VCL | vinculin | -0.0366314 |
| KMT5B | lysine methyltransferase 5B | -0.0364045 |
| OSMR | oncostatin M receptor | -0.036076 |
| NOP58 | NOP58 ribonucleoprotein | -0.0357345 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0355715 |
| UBC | ubiquitin C | -0.0355149 |
| ZNF207 | zinc finger protein 207 | -0.0354828 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0354444 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0352442 |
| VDAC1 | voltage-dependent anion channel 1 | -0.035192 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.034689 |
| IPO7 | importin 7 | -0.034661 |
| NABP1 | nucleic acid binding protein 1 | -0.0346276 |
| ENO1 | enolase 1, (alpha) | -0.0340403 |
| MCL1 | myeloid cell leukemia 1 | -0.0339776 |
| MMP12 | matrix metallopeptidase 12 | -0.0332234 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0331421 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0330893 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0325618 |
| KLF6 | Kruppel-like factor 6 | -0.0323996 |
| TPM4 | tropomyosin 4 | -0.031747 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0312089 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0311316 |
| RAD51B | RAD51 paralog B | -0.0310184 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0304735 |
| EGR1 | early growth response 1 | -0.0302757 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0301737 |
| RPL37 | ribosomal protein L37 | -0.0299434 |
| POTEF | POTE ankyrin domain family, member F | -0.0297498 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0297165 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0295812 |
| ARF4 | ADP-ribosylation factor 4 | -0.0294546 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0293203 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0292788 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0292062 |
| TWF1 | twinfilin actin binding protein 1 | -0.0290227 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0289827 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.028965 |
| ZNF292 | zinc finger protein 292 | -0.0289012 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0287871 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0287287 |
| TMEM165 | transmembrane protein 165 | -0.0286963 |
| PYGL | phosphorylase, glycogen, liver | -0.0283648 |
| CCNL1 | cyclin L1 | -0.0283138 |
| ETNK1 | ethanolamine kinase 1 | -0.0281116 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0279982 |
| LIMA1 | LIM domain and actin binding 1 | -0.0277869 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0276327 |
| FMNL2 | formin-like 2 | -0.0275721 |
| LATS2 | large tumor suppressor kinase 2 | -0.0275684 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.027435 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0274079 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.027405 |
