| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mebendazole perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mebendazole_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.395719 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.229706 |
| ACTG1 | actin gamma 1 | 0.209953 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.117672 |
| TMSB4X | thymosin beta 4, X-linked | 0.117299 |
| CALR | calreticulin | 0.110011 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0979487 |
| NDRG1 | N-myc downstream regulated 1 | 0.0852402 |
| VEGFA | vascular endothelial growth factor A | 0.079963 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0759249 |
| PLEC | plectin | 0.0743575 |
| PLAU | plasminogen activator, urokinase | 0.0700683 |
| SDC4 | syndecan 4 | 0.066332 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0627615 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0619245 |
| G0S2 | G0/G1 switch 2 | 0.0590516 |
| POTEF | POTE ankyrin domain family, member F | 0.0565437 |
| PTMA | prothymosin, alpha | 0.0562749 |
| CCNL1 | cyclin L1 | 0.0553212 |
| LAMB3 | laminin, beta 3 | 0.0525673 |
| TPM3 | tropomyosin 3 | 0.0489474 |
| FLNA | filamin A, alpha | 0.0480525 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0472746 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0470901 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0468011 |
| CTSB | cathepsin B | 0.0442812 |
| RPL7A | ribosomal protein L7a | 0.04408 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0439685 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0424641 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0424548 |
| HLA-B | major histocompatibility complex, class I, B | 0.040968 |
| LAMC2 | laminin, gamma 2 | 0.038881 |
| GPX4 | glutathione peroxidase 4 | 0.037142 |
| ADM | adrenomedullin | 0.0368544 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.036618 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0354106 |
| RBM25 | RNA binding motif protein 25 | 0.035317 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0337784 |
| RPL3 | ribosomal protein L3 | 0.0337578 |
| RPL4 | ribosomal protein L4 | 0.0327569 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0325317 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0320772 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0319078 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0314959 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0307544 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0306314 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0303417 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.03015 |
| RPS3 | ribosomal protein S3 | 0.0286136 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0284089 |
| MSN | moesin | 0.0283534 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0282874 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0278431 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0272317 |
| RPN1 | ribophorin I | 0.0272152 |
| TMSB10 | thymosin beta 10 | 0.0271139 |
| KRT8 | keratin 8, type II | 0.0268211 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0261759 |
| SPAG5 | sperm associated antigen 5 | 0.0255085 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0254923 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0254765 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0254246 |
| APP | amyloid beta (A4) precursor protein | 0.0254207 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0253988 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0252429 |
| TJP2 | tight junction protein 2 | 0.0247215 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0245041 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0240989 |
| HDGF | hepatoma-derived growth factor | 0.0240293 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0239156 |
| PCBP2 | poly(rC) binding protein 2 | 0.0237929 |
| SMAD3 | SMAD family member 3 | 0.0237289 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0236701 |
| SFTPA2 | surfactant protein A2 | 0.0232517 |
| RPL19 | ribosomal protein L19 | 0.0232057 |
| AREG | amphiregulin | 0.0229777 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0229776 |
| RPS17 | ribosomal protein S17 | 0.0229541 |
| FLNB | filamin B, beta | 0.0229492 |
| MT2A | metallothionein 2A | 0.0228646 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0226465 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0226164 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0224464 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0224107 |
| PLAUR | plasminogen activator, urokinase receptor | 0.022401 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0223576 |
| HLA-A | major histocompatibility complex, class I, A | 0.0221558 |
| CLDN4 | claudin 4 | 0.0220266 |
| KRT18 | keratin 18, type I | 0.0218767 |
| DUSP10 | dual specificity phosphatase 10 | 0.0215443 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0211018 |
| RPL13A | ribosomal protein L13a | 0.0208179 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0199785 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.0199548 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0197828 |
| MCL1 | myeloid cell leukemia 1 | 0.019745 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.0197181 |
| PNN | pinin, desmosome associated protein | 0.0195743 |
| MACROH2A1 | macroH2A.1 histone | 0.019548 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.019127 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.265923 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125943 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.10761 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0850021 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0825645 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0685977 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.064568 |
| RPL34 | ribosomal protein L34 | -0.0563158 |
| CANX | calnexin | -0.0536974 |
| CD2AP | CD2-associated protein | -0.0525962 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0480619 |
| RPLP0 | ribosomal protein, large, P0 | -0.0475674 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0470671 |
| S100A6 | S100 calcium binding protein A6 | -0.0469717 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0465975 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0444578 |
| S100A10 | S100 calcium binding protein A10 | -0.0411111 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0403982 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0385836 |
| FBXO32 | F-box protein 32 | -0.0383163 |
| TMEM123 | transmembrane protein 123 | -0.0375398 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0363093 |
| SQSTM1 | sequestosome 1 | -0.0350815 |
| RPS13 | ribosomal protein S13 | -0.0349202 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0342541 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0338598 |
| EFNA5 | ephrin-A5 | -0.0334075 |
| RPLP1 | ribosomal protein, large, P1 | -0.0332872 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0331822 |
| RPS24 | ribosomal protein S24 | -0.0326587 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0323152 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0320138 |
| FNDC3B | fibronectin type III domain containing 3B | -0.03194 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0308395 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0299295 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0294106 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0287246 |
| PGK1 | phosphoglycerate kinase 1 | -0.0287207 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0285737 |
| CEP350 | centrosomal protein 350kDa | -0.0279107 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0278398 |
| VIM | vimentin | -0.0273929 |
| H1-0 | H1.0 linker histone | -0.0273687 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0269397 |
| NF1 | neurofibromin 1 | -0.0261855 |
| RPS25 | ribosomal protein S25 | -0.0256615 |
| FAM162A | family with sequence similarity 162, member A | -0.0255989 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0255928 |
| FTL | ferritin, light polypeptide | -0.0254455 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0251737 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0251321 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0249152 |
| TUBA1B | tubulin, alpha 1b | -0.0248176 |
| CCND1 | cyclin D1 | -0.0248092 |
| SP100 | SP100 nuclear antigen | -0.0247612 |
| ENO1 | enolase 1, (alpha) | -0.0246403 |
| MAP4 | microtubule-associated protein 4 | -0.0242033 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0241704 |
| LMO7 | LIM domain 7 | -0.0239828 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0239519 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0239238 |
| RPS8 | ribosomal protein S8 | -0.0238796 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0237456 |
| MX2 | MX dynamin-like GTPase 2 | -0.0235409 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0234988 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.023452 |
| PLSCR1 | phospholipid scramblase 1 | -0.0231316 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0229605 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0225386 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0225108 |
| CSTB | cystatin B (stefin B) | -0.0222256 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0219823 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0219593 |
| ARF1 | ADP-ribosylation factor 1 | -0.0215266 |
| AHNAK | AHNAK nucleoprotein | -0.021483 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.021423 |
| ERBIN | erbb2 interacting protein | -0.0213586 |
| RAI14 | retinoic acid induced 14 | -0.0212023 |
| CERT1 | ceramide transporter 1 | -0.021006 |
| LDHA | lactate dehydrogenase A | -0.0209922 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0209807 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0209621 |
| RPS27A | ribosomal protein S27a | -0.0209371 |
| RPLP2 | ribosomal protein, large, P2 | -0.0208115 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0205689 |
| RTN3 | reticulon 3 | -0.0204244 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0201815 |
| RPS6 | ribosomal protein S6 | -0.0201602 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0199265 |
| TKT | transketolase | -0.0199217 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.019791 |
| RYBP | RING1 and YY1 binding protein | -0.0196433 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0195996 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0194801 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0194028 |
| VCL | vinculin | -0.0193355 |
| PALLD | palladin, cytoskeletal associated protein | -0.0192731 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.01921 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0191063 |
| DSG2 | desmoglein 2 | -0.0190699 |
