| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mebendazole perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mebendazole_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.124506 |
| CALR | calreticulin | 0.0702167 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0681502 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0634673 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0632568 |
| MKI67 | marker of proliferation Ki-67 | 0.0530285 |
| ACTG1 | actin gamma 1 | 0.048609 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0447126 |
| PTMA | prothymosin, alpha | 0.0437599 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0435262 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0429452 |
| RPL3 | ribosomal protein L3 | 0.0421361 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0401122 |
| THBS1 | thrombospondin 1 | 0.0348178 |
| MYO10 | myosin X | 0.034432 |
| APP | amyloid beta (A4) precursor protein | 0.0333131 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0332094 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.032184 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0319512 |
| YBX1 | Y box binding protein 1 | 0.0318729 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0315173 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0312149 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0304563 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0302534 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0302378 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0301822 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0301098 |
| DCTN1 | dynactin 1 | 0.0297754 |
| RPL7A | ribosomal protein L7a | 0.0295545 |
| WDR43 | WD repeat domain 43 | 0.0280209 |
| PNN | pinin, desmosome associated protein | 0.0277256 |
| MB21D2 | Mab-21 domain containing 2 | 0.0274348 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0274253 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.027205 |
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | 0.0271172 |
| SPAG9 | sperm associated antigen 9 | 0.0270754 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0270664 |
| H1-4 | H1.4 linker histone, cluster member | 0.0263866 |
| STMN1 | stathmin 1 | 0.0260451 |
| SPAG5 | sperm associated antigen 5 | 0.0259085 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0258938 |
| RPL23 | ribosomal protein L23 | 0.0252744 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0252591 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.024851 |
| CNN3 | calponin 3, acidic | 0.0244652 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0240487 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.024022 |
| ANXA5 | annexin A5 | 0.0239907 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0238336 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.023523 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0234161 |
| NUDC | nudC nuclear distribution protein | 0.0232617 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.022778 |
| C1QBP | complement component 1, q subcomponent binding protein | 0.0226027 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0220293 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0218891 |
| UPP1 | uridine phosphorylase 1 | 0.0218653 |
| ADM | adrenomedullin | 0.0216564 |
| VEGFA | vascular endothelial growth factor A | 0.0213328 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0212633 |
| EGFR | epidermal growth factor receptor | 0.0211585 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0211509 |
| FUS | FUS RNA binding protein | 0.0210833 |
| FLNA | filamin A, alpha | 0.0209872 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0209844 |
| CENPF | centromere protein F, 350/400kDa | 0.0208711 |
| RPL26 | ribosomal protein L26 | 0.020818 |
| WDR62 | WD repeat domain 62 | 0.0208068 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0207029 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0206559 |
| RPL13A | ribosomal protein L13a | 0.0205169 |
| PCDH18 | protocadherin 18 | 0.0203354 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0202137 |
| AURKA | aurora kinase A | 0.0200144 |
| AHNAK | AHNAK nucleoprotein | 0.0200128 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.0197555 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0197301 |
| GPX4 | glutathione peroxidase 4 | 0.0196588 |
| TMSB10 | thymosin beta 10 | 0.0195989 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.019425 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0194198 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0192659 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0192057 |
| SIN3A | SIN3 transcription regulator family member A | 0.0191616 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0190996 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0190735 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0190694 |
| RPL4 | ribosomal protein L4 | 0.0189545 |
| NONO | non-POU domain containing, octamer-binding | 0.0187145 |
| PDCD5 | programmed cell death 5 | 0.0186865 |
| CASC3 | cancer susceptibility candidate 3 | 0.0180139 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.017892 |
| ANXA2 | annexin A2 | 0.0178433 |
| NBAS | neuroblastoma amplified sequence | 0.017821 |
| SSRP1 | structure specific recognition protein 1 | 0.0177135 |
| RPN1 | ribophorin I | 0.0176967 |
| PER1 | period circadian clock 1 | 0.0175847 |
| THOC1 | THO complex 1 | 0.0175359 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0174055 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0173429 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.176265 |
| COL11A1 | collagen, type XI, alpha 1 | -0.135858 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.121356 |
| VIM | vimentin | -0.120736 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.116952 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.116896 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.116863 |
| CADM2 | cell adhesion molecule 2 | -0.104034 |
| PEG10 | paternally expressed 10 | -0.098429 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0922663 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0773935 |
| PCDH9 | protocadherin 9 | -0.0766916 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0731269 |
| ITGAV | integrin, alpha V | -0.0721299 |
| PFN1 | profilin 1 | -0.0692104 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0669334 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0668416 |
| GPC3 | glypican 3 | -0.0666612 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0654064 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0650067 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0645464 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0623905 |
| GNAS | GNAS complex locus | -0.0607624 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0600016 |
| RPS16 | ribosomal protein S16 | -0.0598302 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.058916 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0581527 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0566093 |
| PHIP | pleckstrin homology domain interacting protein | -0.0544302 |
| PLPP1 | phospholipid phosphatase 1 | -0.053316 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0531125 |
| MAP4 | microtubule-associated protein 4 | -0.0517443 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0513868 |
| SNX6 | sorting nexin 6 | -0.0505839 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0500725 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0485289 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0482773 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.047209 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.046295 |
| FAM171B | family with sequence similarity 171, member B | -0.0461074 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0455007 |
| MEIS2 | Meis homeobox 2 | -0.0444695 |
| CDH19 | cadherin 19, type 2 | -0.0442597 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0442386 |
| COL1A2 | collagen, type I, alpha 2 | -0.0439064 |
| NRG1 | neuregulin 1 | -0.0436571 |
| PRKD1 | protein kinase D1 | -0.0431844 |
| RBM39 | RNA binding motif protein 39 | -0.0421663 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0418531 |
| GOLGA4 | golgin A4 | -0.0416113 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0412795 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0409204 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0408456 |
| SRP72 | signal recognition particle 72kDa | -0.0404627 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0401785 |
| RLF | rearranged L-myc fusion | -0.0399643 |
| TUBA1B | tubulin, alpha 1b | -0.0395199 |
| PRTG | protogenin | -0.0391058 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0390428 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0389372 |
| RPS8 | ribosomal protein S8 | -0.0389296 |
| LDHA | lactate dehydrogenase A | -0.038209 |
| RAD51B | RAD51 paralog B | -0.0379943 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0379223 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0377212 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0373043 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0370941 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0370808 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0367105 |
| TENM3 | teneurin transmembrane protein 3 | -0.0361506 |
| RTN3 | reticulon 3 | -0.0361146 |
| SMYD3 | SET and MYND domain containing 3 | -0.0356592 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0355963 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.035277 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0352395 |
| STAG2 | stromal antigen 2 | -0.0351756 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0348804 |
| TNRC6B | trinucleotide repeat containing 6B | -0.034765 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0346602 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0345827 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0340874 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0340738 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0340213 |
| CDK6 | cyclin-dependent kinase 6 | -0.0336812 |
| SRP54 | signal recognition particle 54kDa | -0.0334713 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0334399 |
| TJP1 | tight junction protein 1 | -0.0326733 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0326106 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0325347 |
| TFRC | transferrin receptor | -0.032263 |
| RPLP0 | ribosomal protein, large, P0 | -0.0318998 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0317599 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0316694 |
| WASF2 | WAS protein family, member 2 | -0.0313369 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0313159 |
| METAP2 | methionyl aminopeptidase 2 | -0.0312461 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.030999 |
| RDX | radixin | -0.0309245 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0308369 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.030497 |
