| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mebendazole perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mebendazole_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.286016 |
| TMSB4X | thymosin beta 4, X-linked | 0.279842 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.207281 |
| FLNB | filamin B, beta | 0.170498 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.126059 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.106515 |
| ACTG1 | actin gamma 1 | 0.10341 |
| ECT2 | epithelial cell transforming 2 | 0.0954449 |
| RTN4 | reticulon 4 | 0.0922182 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0849856 |
| EZR | ezrin | 0.0824413 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0750188 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0713811 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0711011 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0709024 |
| TXNIP | thioredoxin interacting protein | 0.068937 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.067771 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0676701 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0645219 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0641784 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0640578 |
| LOXL3 | lysyl oxidase-like 3 | 0.0572114 |
| CALR | calreticulin | 0.0541374 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0536762 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.052005 |
| RPL3 | ribosomal protein L3 | 0.0490576 |
| RPL13A | ribosomal protein L13a | 0.0486734 |
| LDHA | lactate dehydrogenase A | 0.0485033 |
| CCNL1 | cyclin L1 | 0.0475605 |
| MKI67 | marker of proliferation Ki-67 | 0.0473618 |
| ZNF292 | zinc finger protein 292 | 0.0463264 |
| RPL7A | ribosomal protein L7a | 0.0443411 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0434359 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0434117 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0431285 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0429391 |
| FAT1 | FAT atypical cadherin 1 | 0.0427897 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.042386 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0421196 |
| TPM4 | tropomyosin 4 | 0.0418508 |
| RPS19 | ribosomal protein S19 | 0.0416394 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.041329 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0405014 |
| B2M | beta-2-microglobulin | 0.0401793 |
| RBM39 | RNA binding motif protein 39 | 0.039675 |
| MYOF | myoferlin | 0.0393936 |
| TPR | translocated promoter region, nuclear basket protein | 0.0391925 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0388115 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0387035 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0385595 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0381686 |
| POTEF | POTE ankyrin domain family, member F | 0.0380143 |
| HDAC9 | histone deacetylase 9 | 0.0379545 |
| RPL35A | ribosomal protein L35a | 0.0377916 |
| RPL19 | ribosomal protein L19 | 0.0377906 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0376783 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0376553 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0371356 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0367662 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0364854 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0363024 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0362683 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0362303 |
| RBM25 | RNA binding motif protein 25 | 0.0352579 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0348075 |
| PFN1 | profilin 1 | 0.0346353 |
| ANXA2 | annexin A2 | 0.0345766 |
| USP3 | ubiquitin specific peptidase 3 | 0.0343463 |
| MATR3 | matrin 3 | 0.0341883 |
| PCBP2 | poly(rC) binding protein 2 | 0.0341878 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0338971 |
| QKI | QKI, KH domain containing, RNA binding | 0.0337847 |
| RPL23 | ribosomal protein L23 | 0.0337521 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0332755 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0329254 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0327767 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0327316 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0322857 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0320391 |
| APP | amyloid beta (A4) precursor protein | 0.0319562 |
| RNF145 | ring finger protein 145 | 0.0315326 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0313831 |
| AHNAK | AHNAK nucleoprotein | 0.0313753 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0310169 |
| TMSB10 | thymosin beta 10 | 0.0307276 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0307209 |
| RPS6 | ribosomal protein S6 | 0.0305982 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0303658 |
| ITGA6 | integrin, alpha 6 | 0.030221 |
| TJP1 | tight junction protein 1 | 0.0302143 |
| MT2A | metallothionein 2A | 0.0298983 |
| PTK2 | protein tyrosine kinase 2 | 0.0297895 |
| RPL12 | ribosomal protein L12 | 0.0296484 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0296455 |
| EMP1 | epithelial membrane protein 1 | 0.0296455 |
| HSPA8 | heat shock 70kDa protein 8 | 0.029487 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0294254 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0294152 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0290749 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.029046 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0729562 |
| RPS2 | ribosomal protein S2 | -0.0537625 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.044479 |
| VCL | vinculin | -0.043306 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0404062 |
| BMP10 | bone morphogenetic protein 10 | -0.0356251 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0343181 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0339847 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0334006 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0323546 |
| FOXP1 | forkhead box P1 | -0.0319472 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0310263 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.027527 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0264547 |
| EFNA5 | ephrin-A5 | -0.0262861 |
| CCND1 | cyclin D1 | -0.0257837 |
| BMP2K | BMP2 inducible kinase | -0.0251351 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0239892 |
| EGFR | epidermal growth factor receptor | -0.0238793 |
| GPHN | gephyrin | -0.0230573 |
| MACROD2 | MACRO domain containing 2 | -0.0213962 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0209681 |
| AEBP2 | AE binding protein 2 | -0.0208752 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0206273 |
| CDK13 | cyclin-dependent kinase 13 | -0.0195279 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0192082 |
| RAB10 | RAB10, member RAS oncogene family | -0.0186442 |
| ZNF217 | zinc finger protein 217 | -0.0178617 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0177315 |
| PDE7B | phosphodiesterase 7B | -0.0175875 |
| EHBP1 | EH domain binding protein 1 | -0.0175069 |
| GPATCH8 | G patch domain containing 8 | -0.0173142 |
| RFX7 | regulatory factor X, 7 | -0.0172563 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0166263 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0163396 |
| MYO9A | myosin IXA | -0.0161223 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0158654 |
| NFIA | nuclear factor I/A | -0.0157447 |
| CEP350 | centrosomal protein 350kDa | -0.0157347 |
| KIAA0232 | KIAA0232 | -0.0156874 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0151117 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0150144 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0149666 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0147569 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0147555 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0147018 |
| SQSTM1 | sequestosome 1 | -0.0145513 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0142501 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0141373 |
| TUBA1B | tubulin, alpha 1b | -0.0138465 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0134308 |
| IRS1 | insulin receptor substrate 1 | -0.0131669 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0131385 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0130741 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0130523 |
| ONECUT2 | one cut homeobox 2 | -0.0128716 |
| MYO5C | myosin VC | -0.0127937 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0127927 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0127762 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0126265 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0125616 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0124186 |
| COMMD10 | COMM domain containing 10 | -0.0121418 |
| RPL34 | ribosomal protein L34 | -0.0120136 |
| PKP4 | plakophilin 4 | -0.0119243 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0118497 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0117189 |
| TOB1 | transducer of ERBB2, 1 | -0.0117166 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.011675 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0115981 |
| S100A4 | S100 calcium binding protein A4 | -0.0115591 |
| ANKRD13C | ankyrin repeat domain 13C | -0.0113569 |
| RPL14 | ribosomal protein L14 | -0.0113453 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0113278 |
| SETX | senataxin | -0.0113225 |
| CDK14 | cyclin-dependent kinase 14 | -0.011033 |
| TXNRD1 | thioredoxin reductase 1 | -0.011013 |
| TUBB | tubulin, beta class I | -0.0109769 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0108979 |
| FCHO2 | FCH domain only 2 | -0.01084 |
| ZNF37A | zinc finger protein 37A | -0.0107197 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.010532 |
| BPTF | bromodomain PHD finger transcription factor | -0.0104902 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0104569 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0104559 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0104482 |
| ARMH4 | armadillo like helical domain containing 4 | -0.01041 |
| ZNF407 | zinc finger protein 407 | -0.0103956 |
| ZNF638 | zinc finger protein 638 | -0.0103902 |
| BBX | bobby sox homolog (Drosophila) | -0.0103469 |
| RDX | radixin | -0.0102997 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0102888 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0102322 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0102177 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0102112 |
| MTAP | methylthioadenosine phosphorylase | -0.0100987 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0100979 |
| KIF16B | kinesin family member 16B | -0.0100875 |
| CCDC138 | coiled-coil domain containing 138 | -0.0100656 |
| ZNF800 | zinc finger protein 800 | -0.0100287 |
