Medroxyprogesterone Acetate Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A steroid ester that has formula C24H34O4. (Chemical Entities of Biological Interest Ontology, CHEBI_6716)
External Link http://ctdbase.org/detail.go?type=chem&acc=D017258
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Genes

68 genes/proteins interacting with the chemical Medroxyprogesterone Acetate from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
AR androgen receptor
BAX BCL2-associated X protein
BCL2L11 BCL2-like 11 (apoptosis facilitator)
CCL2 chemokine (C-C motif) ligand 2
CCNB1 cyclin B1
CCND1 cyclin D1
CD40LG CD40 ligand
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFLAR CASP8 and FADD-like apoptosis regulator
CREBBP CREB binding protein
CRP C-reactive protein, pentraxin-related
CYBB cytochrome b-245, beta polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DCN decorin
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FASLG Fas ligand (TNF superfamily, member 6)
FBLN1 fibulin 1
FN1 fibronectin 1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FSHB follicle stimulating hormone, beta polypeptide
GADD45A growth arrest and DNA-damage-inducible, alpha
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGFBP1 insulin-like growth factor binding protein 1
IL1B interleukin 1, beta
IL2 interleukin 2
IL6 interleukin 6
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
NCF2 neutrophil cytosolic factor 2
NCOA1 nuclear receptor coactivator 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PGR progesterone receptor
PRL prolactin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SIRT1 sirtuin 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
TNF tumor necrosis factor
TP53 tumor protein p53
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIM vimentin
WNT5A wingless-type MMTV integration site family, member 5A