| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.342942 |
| PLAT | plasminogen activator, tissue | 0.17921 |
| LOX | lysyl oxidase | 0.12861 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.101519 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.099169 |
| COL5A1 | collagen, type V, alpha 1 | 0.0881185 |
| LOXL2 | lysyl oxidase-like 2 | 0.0871947 |
| NAV1 | neuron navigator 1 | 0.0838356 |
| THBS2 | thrombospondin 2 | 0.0815806 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0805851 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.078752 |
| MYADM | myeloid-associated differentiation marker | 0.0777974 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0759952 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0756331 |
| FLNA | filamin A, alpha | 0.0683492 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0654871 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0622948 |
| LDHA | lactate dehydrogenase A | 0.060817 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0558938 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0556507 |
| FLNB | filamin B, beta | 0.0553039 |
| PKM | pyruvate kinase, muscle | 0.0543748 |
| EGFR | epidermal growth factor receptor | 0.0499202 |
| CD44 | CD44 molecule (Indian blood group) | 0.0470615 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0466586 |
| L1CAM | L1 cell adhesion molecule | 0.0465205 |
| C1D | C1D nuclear receptor corepressor | 0.0460809 |
| SEPTIN9 | septin 9 | 0.0438957 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.043619 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0430204 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.041822 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0417809 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0399935 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0383279 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0380241 |
| EFNA5 | ephrin-A5 | 0.0357034 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.035506 |
| CD99 | CD99 molecule | 0.0350759 |
| DCLK2 | doublecortin-like kinase 2 | 0.0347767 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.033701 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.033368 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0320995 |
| RRM2 | ribonucleotide reductase M2 | 0.0319831 |
| NAV2 | neuron navigator 2 | 0.031462 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0303845 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.029342 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0282407 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0262567 |
| PGK1 | phosphoglycerate kinase 1 | 0.0258838 |
| GSE1 | Gse1 coiled-coil protein | 0.0253899 |
| MKI67 | marker of proliferation Ki-67 | 0.0251323 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0247077 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0245246 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0244746 |
| CTSB | cathepsin B | 0.0242517 |
| BCL2L1 | BCL2-like 1 | 0.024171 |
| SYTL3 | synaptotagmin-like 3 | 0.0235603 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0232147 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0230967 |
| GANAB | glucosidase, alpha; neutral AB | 0.0230362 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0229187 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0226747 |
| DNMBP | dynamin binding protein | 0.022652 |
| PLEC | plectin | 0.0223469 |
| MEF2D | myocyte enhancer factor 2D | 0.0221403 |
| OSMR | oncostatin M receptor | 0.0221266 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0220002 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0219031 |
| PFKP | phosphofructokinase, platelet | 0.0217005 |
| FOSL1 | FOS-like antigen 1 | 0.021457 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0213602 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0211669 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0210116 |
| TRAM2 | translocation associated membrane protein 2 | 0.0206143 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0204247 |
| NDRG1 | N-myc downstream regulated 1 | 0.0203549 |
| RNF144A | ring finger protein 144A | 0.0201948 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0201447 |
| RUNX1 | runt-related transcription factor 1 | 0.0200283 |
| YEATS2 | YEATS domain containing 2 | 0.0198363 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0197361 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.019502 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0191302 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0188533 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.0188502 |
| SFTPA2 | surfactant protein A2 | 0.0188323 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0186961 |
| MCL1 | myeloid cell leukemia 1 | 0.0183464 |
| PLXNA2 | plexin A2 | 0.0182045 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0178322 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0178271 |
| MRC2 | mannose receptor, C type 2 | 0.0178099 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0176629 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0175925 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0175871 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0175691 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0174816 |
| PRKCE | protein kinase C, epsilon | 0.0172856 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0170335 |
| NFASC | neurofascin | 0.0167934 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.303317 |
| VIM | vimentin | -0.192269 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.126901 |
| PTMA | prothymosin, alpha | -0.0944884 |
| S100A10 | S100 calcium binding protein A10 | -0.0922494 |
| FBN1 | fibrillin 1 | -0.0892471 |
| AHNAK | AHNAK nucleoprotein | -0.0639784 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.062163 |
| LMNA | lamin A/C | -0.061904 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.057265 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0553605 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0523254 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0515905 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0504139 |
| FTL | ferritin, light polypeptide | -0.0473314 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0470028 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0463714 |
| SQSTM1 | sequestosome 1 | -0.0454675 |
| TMSB4X | thymosin beta 4, X-linked | -0.0451756 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0429161 |
| MT2A | metallothionein 2A | -0.0426573 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0425085 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0417828 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0409938 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0409921 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0403963 |
| B2M | beta-2-microglobulin | -0.0403278 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.040152 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0400631 |
| UBC | ubiquitin C | -0.0389191 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0385096 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0380535 |
| COL3A1 | collagen, type III, alpha 1 | -0.0377881 |
| COL1A2 | collagen, type I, alpha 2 | -0.0373161 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0365908 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.036488 |
| HLA-B | major histocompatibility complex, class I, B | -0.0361285 |
| OGA | O-GlcNAcase | -0.0360171 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0356342 |
| SP100 | SP100 nuclear antigen | -0.0355865 |
| RPS24 | ribosomal protein S24 | -0.0355013 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0353614 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0353171 |
| AUTS2 | autism susceptibility candidate 2 | -0.0337015 |
| RIGI | RNA sensor RIG-I | -0.0336246 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0327073 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0326331 |
| MSI2 | musashi RNA-binding protein 2 | -0.032529 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0321735 |
| CANX | calnexin | -0.032081 |
| SPAG9 | sperm associated antigen 9 | -0.0320243 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0309626 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0307489 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0302557 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0302456 |
| GPC6 | glypican 6 | -0.0297446 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0294385 |
| TPM1 | tropomyosin 1 (alpha) | -0.0288673 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0288235 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0280914 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0278173 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0276558 |
| TAGLN2 | transgelin 2 | -0.0272433 |
| MAP1B | microtubule-associated protein 1B | -0.0268169 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0268007 |
| RRBP1 | ribosome binding protein 1 | -0.0267104 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0265706 |
| CSTB | cystatin B (stefin B) | -0.0264242 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0263722 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0262849 |
| IER3 | immediate early response 3 | -0.0262785 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0261413 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0259671 |
| VCL | vinculin | -0.0255338 |
| MEIS2 | Meis homeobox 2 | -0.0249846 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0248885 |
| RPL19 | ribosomal protein L19 | -0.0246022 |
| WTAP | Wilms tumor 1 associated protein | -0.0244751 |
| GOLGA4 | golgin A4 | -0.0235639 |
| HLA-C | major histocompatibility complex, class I, C | -0.0234143 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.02339 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.023383 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0232483 |
| TFG | TRK-fused gene | -0.0231894 |
| MT1X | metallothionein 1X | -0.0231298 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0229833 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0228805 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0227946 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0225309 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0222335 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0219424 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0219245 |
| FMNL2 | formin-like 2 | -0.0217974 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0217296 |
| RPS19 | ribosomal protein S19 | -0.0215802 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0214226 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0213696 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0212696 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0212619 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0211974 |
