| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.249498 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.152719 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.142661 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.138732 |
| ACTG1 | actin gamma 1 | 0.114036 |
| NLGN1 | neuroligin 1 | 0.097837 |
| PGK1 | phosphoglycerate kinase 1 | 0.0888623 |
| YAP1 | Yes-associated protein 1 | 0.0884189 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0846353 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0831502 |
| NHSL1 | NHS-like 1 | 0.0764576 |
| RRM2 | ribonucleotide reductase M2 | 0.074647 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0667316 |
| ASPH | aspartate beta-hydroxylase | 0.0661985 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0620589 |
| HMGA2 | high mobility group AT-hook 2 | 0.0613918 |
| EGR1 | early growth response 1 | 0.0606335 |
| LDHA | lactate dehydrogenase A | 0.0577209 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.056435 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.056194 |
| LDHB | lactate dehydrogenase B | 0.0541397 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0533551 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0503007 |
| CCN2 | cellular communication network factor 2 | 0.0498722 |
| TUBA1B | tubulin, alpha 1b | 0.0488888 |
| ENO1 | enolase 1, (alpha) | 0.0484097 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0484067 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0475865 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.046661 |
| TPI1 | triosephosphate isomerase 1 | 0.0465418 |
| TGM2 | transglutaminase 2 | 0.0451762 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0451084 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0446137 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0441833 |
| TUBA1C | tubulin, alpha 1c | 0.0420361 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0394216 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0391335 |
| MMP12 | matrix metallopeptidase 12 | 0.03787 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0378567 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0368378 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0361745 |
| MYADM | myeloid-associated differentiation marker | 0.0360764 |
| CALR | calreticulin | 0.0352236 |
| POTEF | POTE ankyrin domain family, member F | 0.0345623 |
| BCHE | butyrylcholinesterase | 0.0340356 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0337695 |
| HMGA1 | high mobility group AT-hook 1 | 0.0335454 |
| PKM | pyruvate kinase, muscle | 0.0335416 |
| RPS26 | ribosomal protein S26 | 0.0333747 |
| RPL9 | ribosomal protein L9 | 0.033012 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0329268 |
| MKI67 | marker of proliferation Ki-67 | 0.0324509 |
| FAT4 | FAT atypical cadherin 4 | 0.0324505 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.0321651 |
| PCDH9 | protocadherin 9 | 0.0317181 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0313421 |
| FAT1 | FAT atypical cadherin 1 | 0.0313136 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.031183 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0308633 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0306583 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0303537 |
| RTN4 | reticulon 4 | 0.0302693 |
| EHBP1 | EH domain binding protein 1 | 0.0301988 |
| RHOA | ras homolog family member A | 0.0294031 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0293853 |
| TMEM41B | transmembrane protein 41B | 0.0287157 |
| CLTC | clathrin, heavy chain (Hc) | 0.0285203 |
| GCG | glucagon | 0.0282668 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0282572 |
| PRDX1 | peroxiredoxin 1 | 0.0281694 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0281422 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0276137 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0271536 |
| PRKCE | protein kinase C, epsilon | 0.0269169 |
| ANXA1 | annexin A1 | 0.0267528 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0262004 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.026156 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0260733 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0260286 |
| RPS2 | ribosomal protein S2 | 0.0253574 |
| NAV3 | neuron navigator 3 | 0.0251086 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.025016 |
| TPM3 | tropomyosin 3 | 0.0249454 |
| RNF213 | ring finger protein 213 | 0.0249137 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0243245 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0243134 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.024158 |
| TPM4 | tropomyosin 4 | 0.0238624 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0238165 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0235792 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0235536 |
| NEBL | nebulette | 0.0233949 |
| RANBP17 | RAN binding protein 17 | 0.0231336 |
| ANXA5 | annexin A5 | 0.0231209 |
| OSMR | oncostatin M receptor | 0.023041 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0229586 |
| SESN2 | sestrin 2 | 0.0229025 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0228447 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0227084 |
| FLNA | filamin A, alpha | 0.0227048 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.222967 |
| AREG | amphiregulin | -0.147044 |
| VIM | vimentin | -0.117108 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0774104 |
| PTMA | prothymosin, alpha | -0.0622205 |
| FTL | ferritin, light polypeptide | -0.06106 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0527688 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.051557 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0447239 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0441387 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0416068 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0410095 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0392245 |
| MGAT4C | MGAT4 family, member C | -0.0390448 |
| CLDN1 | claudin 1 | -0.0384355 |
| EDN1 | endothelin 1 | -0.036104 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0358845 |
| OXR1 | oxidation resistance 1 | -0.0353899 |
| ECT2 | epithelial cell transforming 2 | -0.0353537 |
| NEK7 | NIMA-related kinase 7 | -0.0352924 |
| CPOX | coproporphyrinogen oxidase | -0.0347781 |
| RPS12 | ribosomal protein S12 | -0.0341807 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0339903 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0339278 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0337628 |
| RPL19 | ribosomal protein L19 | -0.0336929 |
| RPS24 | ribosomal protein S24 | -0.0327984 |
| RBM39 | RNA binding motif protein 39 | -0.0326398 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0325914 |
| ZNF217 | zinc finger protein 217 | -0.0313553 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0312554 |
| YBX1 | Y box binding protein 1 | -0.0307204 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0306481 |
| TMEM131 | transmembrane protein 131 | -0.0305741 |
| OGA | O-GlcNAcase | -0.030572 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0303637 |
| SYT1 | synaptotagmin I | -0.0299871 |
| ZNF292 | zinc finger protein 292 | -0.0298478 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0296853 |
| RPL26 | ribosomal protein L26 | -0.0293455 |
| KLHL24 | kelch-like family member 24 | -0.0291942 |
| SPAG9 | sperm associated antigen 9 | -0.0287253 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0286831 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0286163 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0286082 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0285053 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0284711 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0282104 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0279467 |
| RPS5 | ribosomal protein S5 | -0.0278622 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0274441 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0273341 |
| USP15 | ubiquitin specific peptidase 15 | -0.0272801 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0271396 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0271328 |
| RPS3 | ribosomal protein S3 | -0.0270959 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0270716 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0269748 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0269608 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0266908 |
| NF1 | neurofibromin 1 | -0.0266568 |
| CDK6 | cyclin-dependent kinase 6 | -0.0265569 |
| RPL5 | ribosomal protein L5 | -0.0264829 |
| QKI | QKI, KH domain containing, RNA binding | -0.0263313 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0262914 |
| CEP95 | centrosomal protein 95kDa | -0.0261186 |
| ZNF804A | zinc finger protein 804A | -0.0259562 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0255057 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0254944 |
| PTMS | parathymosin | -0.0253856 |
| THOC1 | THO complex 1 | -0.0253122 |
| THOC2 | THO complex 2 | -0.02486 |
| VMP1 | vacuole membrane protein 1 | -0.0248108 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0246009 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0245976 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0244727 |
| POU2F1 | POU class 2 homeobox 1 | -0.0242641 |
| AHNAK | AHNAK nucleoprotein | -0.0239134 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0235666 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0228353 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0227616 |
| LMO7 | LIM domain 7 | -0.022444 |
| PLK2 | polo-like kinase 2 | -0.0224329 |
| RPL31 | ribosomal protein L31 | -0.0223467 |
| FBXO11 | F-box protein 11 | -0.022316 |
| RLF | rearranged L-myc fusion | -0.0222725 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.022271 |
| RPL32 | ribosomal protein L32 | -0.0222448 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0221485 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0221415 |
| USP34 | ubiquitin specific peptidase 34 | -0.0220694 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.021906 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0218848 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0218329 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0215408 |
| SQSTM1 | sequestosome 1 | -0.0214273 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0213206 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0212612 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0212602 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0210719 |
