| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.184412 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.128793 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0834238 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.075504 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0656265 |
| TGM2 | transglutaminase 2 | 0.0645705 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0539449 |
| LDHA | lactate dehydrogenase A | 0.0490817 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0487329 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0475933 |
| OSMR | oncostatin M receptor | 0.047256 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0455561 |
| ANGPTL4 | angiopoietin-like 4 | 0.0428037 |
| RHCG | Rh family, C glycoprotein | 0.0419064 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0410077 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0404856 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.038914 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0380953 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0359051 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0356826 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0349337 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0348002 |
| FAT1 | FAT atypical cadherin 1 | 0.0345178 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0344499 |
| WWC1 | WW and C2 domain containing 1 | 0.0342646 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0341126 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0336385 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0335701 |
| LPIN2 | lipin 2 | 0.0326134 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0320288 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.031359 |
| RNF145 | ring finger protein 145 | 0.030188 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0296307 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0287929 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0281433 |
| FLNA | filamin A, alpha | 0.0268984 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0254728 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0251337 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0247897 |
| BCL2L1 | BCL2-like 1 | 0.0246124 |
| STOM | stomatin | 0.0241696 |
| KLF6 | Kruppel-like factor 6 | 0.0239499 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0237467 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0235508 |
| HPCAL1 | hippocalcin-like 1 | 0.0228471 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0226684 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0225797 |
| PON2 | paraoxonase 2 | 0.0221065 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0215947 |
| RPL4 | ribosomal protein L4 | 0.0213237 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0212268 |
| ITGB5 | integrin, beta 5 | 0.0211081 |
| SGMS1 | sphingomyelin synthase 1 | 0.0210659 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0209714 |
| GPRIN3 | GPRIN family member 3 | 0.0205701 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0204188 |
| WWOX | WW domain containing oxidoreductase | 0.0198693 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0198463 |
| KRT7 | keratin 7, type II | 0.0194813 |
| BMP6 | bone morphogenetic protein 6 | 0.0192751 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0189904 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0189518 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0184046 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0183543 |
| FKBP5 | FK506 binding protein 5 | 0.0181562 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0180277 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0178859 |
| PGK1 | phosphoglycerate kinase 1 | 0.017539 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0175088 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0174041 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.017334 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0169588 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0169504 |
| MLKL | mixed lineage kinase domain-like | 0.016906 |
| DUSP12 | dual specificity phosphatase 12 | 0.0168262 |
| FOSL2 | FOS-like antigen 2 | 0.0168037 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0167918 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0167455 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0166343 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0166191 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.016352 |
| LAMA5 | laminin, alpha 5 | 0.0163319 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0162583 |
| CD68 | CD68 molecule | 0.0162384 |
| IRS2 | insulin receptor substrate 2 | 0.0161889 |
| EXOC6B | exocyst complex component 6B | 0.0160821 |
| EGR1 | early growth response 1 | 0.0160339 |
| IL15 | interleukin 15 | 0.0160051 |
| CCNL1 | cyclin L1 | 0.0158815 |
| AXL | AXL receptor tyrosine kinase | 0.0158779 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0155553 |
| RPS2 | ribosomal protein S2 | 0.0154935 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0153381 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0152655 |
| CSNK1D | casein kinase 1, delta | 0.014914 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0146586 |
| EREG | epiregulin | 0.014385 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0142084 |
| MYADM | myeloid-associated differentiation marker | 0.0141997 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0141361 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.194059 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.136755 |
| FTL | ferritin, light polypeptide | -0.109952 |
| NDRG1 | N-myc downstream regulated 1 | -0.108792 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.103131 |
| VIM | vimentin | -0.102443 |
| PTMA | prothymosin, alpha | -0.0948815 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.085646 |
| VCL | vinculin | -0.0815284 |
| ASPH | aspartate beta-hydroxylase | -0.0796219 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0737754 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0729168 |
| RPS19 | ribosomal protein S19 | -0.0718225 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0706934 |
| AUTS2 | autism susceptibility candidate 2 | -0.0692417 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0691242 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0686542 |
| GRB10 | growth factor receptor-bound protein 10 | -0.066551 |
| PARD3 | par-3 family cell polarity regulator | -0.066034 |
| RPS27A | ribosomal protein S27a | -0.0656386 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0653857 |
| AHNAK | AHNAK nucleoprotein | -0.0630487 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.059305 |
| CANX | calnexin | -0.0590979 |
| UBC | ubiquitin C | -0.0585699 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0581256 |
| RPL23 | ribosomal protein L23 | -0.0579213 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.055559 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0545393 |
| TBC1D22A | TBC1 domain family, member 22A | -0.05239 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0512426 |
| SPAG9 | sperm associated antigen 9 | -0.0510075 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0497313 |
| EHBP1 | EH domain binding protein 1 | -0.0489513 |
| GOLGB1 | golgin B1 | -0.0487559 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0476534 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0475234 |
| TPM1 | tropomyosin 1 (alpha) | -0.0474591 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0460776 |
| RPS24 | ribosomal protein S24 | -0.0455155 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0453682 |
| FBXO11 | F-box protein 11 | -0.0452786 |
| FMNL2 | formin-like 2 | -0.0445033 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0440584 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0436813 |
| USP3 | ubiquitin specific peptidase 3 | -0.0432352 |
| EGFR | epidermal growth factor receptor | -0.0430638 |
| PRKCA | protein kinase C, alpha | -0.0430033 |
| PDE10A | phosphodiesterase 10A | -0.0416246 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.041513 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0413878 |
| GPC6 | glypican 6 | -0.0411752 |
| S100A10 | S100 calcium binding protein A10 | -0.0408154 |
| ENO1 | enolase 1, (alpha) | -0.0404858 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0395657 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0394343 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0384217 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0382557 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0376923 |
| RPS6 | ribosomal protein S6 | -0.037008 |
| FAM107B | family with sequence similarity 107, member B | -0.0368629 |
| RRBP1 | ribosome binding protein 1 | -0.0366089 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0358711 |
| TNS3 | tensin 3 | -0.035732 |
| RPS8 | ribosomal protein S8 | -0.0357293 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0355473 |
| RPS3 | ribosomal protein S3 | -0.0355183 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0348643 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0347008 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0345672 |
| GOLGA4 | golgin A4 | -0.0344909 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0342612 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.034203 |
| NAV2 | neuron navigator 2 | -0.0341363 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0340338 |
| SP100 | SP100 nuclear antigen | -0.0339056 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.033784 |
| RAI14 | retinoic acid induced 14 | -0.0336882 |
| MORF4L2 | mortality factor 4 like 2 | -0.0335684 |
| SQSTM1 | sequestosome 1 | -0.0335346 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0333591 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0332055 |
| MYO10 | myosin X | -0.0329132 |
| EFNA5 | ephrin-A5 | -0.0322379 |
| CD44 | CD44 molecule (Indian blood group) | -0.0321703 |
| ANXA2 | annexin A2 | -0.0319397 |
| RPL31 | ribosomal protein L31 | -0.0313651 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0313572 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0312091 |
| AADAC | arylacetamide deacetylase | -0.0311457 |
| MYOF | myoferlin | -0.030957 |
| RPLP2 | ribosomal protein, large, P2 | -0.0308504 |
| HELZ | helicase with zinc finger | -0.0301547 |
| SMAD3 | SMAD family member 3 | -0.0301174 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0297773 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0297472 |
| RPL19 | ribosomal protein L19 | -0.0297174 |
| PTK2 | protein tyrosine kinase 2 | -0.0297071 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0297036 |
| CMIP | c-Maf inducing protein | -0.0295425 |
