| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.13863 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.111465 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.105937 |
| MKI67 | marker of proliferation Ki-67 | 0.0634982 |
| PDE10A | phosphodiesterase 10A | 0.0482366 |
| FN1 | fibronectin 1 | 0.0390331 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0322438 |
| TNPO1 | transportin 1 | 0.0303225 |
| GSE1 | Gse1 coiled-coil protein | 0.0290932 |
| IGF2 | insulin-like growth factor 2 | 0.0285762 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.026258 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0260363 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0249592 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0245791 |
| KIF11 | kinesin family member 11 | 0.0240562 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0234629 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0232161 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0230989 |
| HMGA1 | high mobility group AT-hook 1 | 0.023097 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.022916 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0227966 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0226221 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0223898 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | 0.0222358 |
| PCDH7 | protocadherin 7 | 0.0222159 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0219661 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 0.0218907 |
| NAV2 | neuron navigator 2 | 0.0218357 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0217195 |
| PGK1 | phosphoglycerate kinase 1 | 0.0213328 |
| ANXA5 | annexin A5 | 0.0210062 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0207419 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0201886 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.0198647 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0198296 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0195842 |
| EXOC5 | exocyst complex component 5 | 0.0195187 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0192995 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0192661 |
| PHF14 | PHD finger protein 14 | 0.0192519 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0192133 |
| MT2A | metallothionein 2A | 0.0190387 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.0186544 |
| RPL13A | ribosomal protein L13a | 0.0185847 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.018181 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0181782 |
| KIF23 | kinesin family member 23 | 0.0175736 |
| ACTG1 | actin gamma 1 | 0.0174987 |
| FRYL | FRY-like | 0.0174811 |
| PKM | pyruvate kinase, muscle | 0.0172355 |
| GANAB | glucosidase, alpha; neutral AB | 0.017177 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | 0.0169313 |
| CIP2A | cellular inhibitor of PP2A | 0.0167984 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0166908 |
| ARRDC3 | arrestin domain containing 3 | 0.0166855 |
| RNF8 | ring finger protein 8, E3 ubiquitin protein ligase | 0.0166495 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0165905 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | 0.016431 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0164016 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0161245 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.0160839 |
| INO80 | INO80 complex subunit | 0.0159866 |
| CCNL1 | cyclin L1 | 0.0159167 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0158722 |
| CENPE | centromere protein E, 312kDa | 0.0158472 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0157848 |
| HELLS | helicase, lymphoid-specific | 0.0155147 |
| BCOR | BCL6 corepressor | 0.015323 |
| DEPDC1B | DEP domain containing 1B | 0.0153206 |
| MRPS27 | mitochondrial ribosomal protein S27 | 0.0152554 |
| TUBB | tubulin, beta class I | 0.0151881 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0149386 |
| CDC27 | cell division cycle 27 | 0.014882 |
| BOC | BOC cell adhesion associated, oncogene regulated | 0.0148475 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0145909 |
| CBFB | core-binding factor, beta subunit | 0.0145645 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0145327 |
| PON2 | paraoxonase 2 | 0.0143916 |
| CLTC | clathrin, heavy chain (Hc) | 0.0143328 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0141727 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0141713 |
| SMAD3 | SMAD family member 3 | 0.0141501 |
| DST | dystonin | 0.0141205 |
| EHBP1 | EH domain binding protein 1 | 0.0140687 |
| FUS | FUS RNA binding protein | 0.013993 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.013975 |
| ANLN | anillin, actin binding protein | 0.013952 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0138833 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0138652 |
| SELENON | selenoprotein N | 0.0138343 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.0137259 |
| PLEC | plectin | 0.0136967 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0136599 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0136176 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.013515 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0134934 |
| NUP153 | nucleoporin 153kDa | 0.0134866 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0134634 |
| SPAG9 | sperm associated antigen 9 | 0.0134608 |
| RPS2 | ribosomal protein S2 | 0.0134284 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.184438 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.122358 |
| PTMA | prothymosin, alpha | -0.102672 |
| PEG10 | paternally expressed 10 | -0.0947723 |
| IER3 | immediate early response 3 | -0.0807089 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0771865 |
| MGP | matrix Gla protein | -0.0771536 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0722325 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0709077 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0665278 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0651618 |
| QKI | QKI, KH domain containing, RNA binding | -0.06244 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0622893 |
| TMSB10 | thymosin beta 10 | -0.0573741 |
| JMJD1C | jumonji domain containing 1C | -0.0487669 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0460701 |
| RPS8 | ribosomal protein S8 | -0.0445249 |
| RPS24 | ribosomal protein S24 | -0.0442867 |
| TMSB4X | thymosin beta 4, X-linked | -0.0437339 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0434832 |
| CANX | calnexin | -0.0400906 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0400728 |
| AFF4 | AF4/FMR2 family, member 4 | -0.039707 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0389356 |
| FBXO11 | F-box protein 11 | -0.0373414 |
| CADM2 | cell adhesion molecule 2 | -0.0368926 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0349585 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0348271 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0345762 |
| HMGA2 | high mobility group AT-hook 2 | -0.0345379 |
| NBEA | neurobeachin | -0.0335794 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0332833 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0321608 |
| RPS12 | ribosomal protein S12 | -0.0321605 |
| MED13L | mediator complex subunit 13-like | -0.0315307 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0313188 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0311453 |
| YBX1 | Y box binding protein 1 | -0.0309783 |
| RPL37A | ribosomal protein L37a | -0.0305534 |
| COL1A2 | collagen, type I, alpha 2 | -0.0300053 |
| NFIB | nuclear factor I/B | -0.0297785 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0294843 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.028955 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0287588 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0281544 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0281304 |
| SIK3 | SIK family kinase 3 | -0.0274805 |
| RPS3 | ribosomal protein S3 | -0.0272423 |
| RPL31 | ribosomal protein L31 | -0.0272159 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0271219 |
| STRBP | spermatid perinuclear RNA binding protein | -0.0266576 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0265644 |
| RPS17 | ribosomal protein S17 | -0.0258001 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0256385 |
| KAZN | kazrin, periplakin interacting protein | -0.0255819 |
| RPS23 | ribosomal protein S23 | -0.0255716 |
| OGA | O-GlcNAcase | -0.0255052 |
| PHF3 | PHD finger protein 3 | -0.0253156 |
| RPL5 | ribosomal protein L5 | -0.0250771 |
| PARD3 | par-3 family cell polarity regulator | -0.0248404 |
| ZFHX3 | zinc finger homeobox 3 | -0.0248172 |
| MEOX2 | mesenchyme homeobox 2 | -0.0246429 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0244586 |
| GPHN | gephyrin | -0.0243042 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0243004 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0241216 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.0240818 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0238274 |
| FAM168A | family with sequence similarity 168, member A | -0.0238141 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0236566 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.023503 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0234621 |
| EGFR | epidermal growth factor receptor | -0.0234195 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0232696 |
| RSU1 | Ras suppressor protein 1 | -0.0232012 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0231889 |
| RPS27A | ribosomal protein S27a | -0.0231505 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0230322 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0224739 |
| FTL | ferritin, light polypeptide | -0.0223701 |
| TNRC6B | trinucleotide repeat containing 6B | -0.022286 |
| RPS25 | ribosomal protein S25 | -0.022256 |
| RPS6 | ribosomal protein S6 | -0.0221843 |
| SQSTM1 | sequestosome 1 | -0.0221 |
| COMMD10 | COMM domain containing 10 | -0.0220675 |
| SHROOM3 | shroom family member 3 | -0.0220522 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0219801 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0218912 |
| ERBIN | erbb2 interacting protein | -0.0218317 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0218282 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0217517 |
| HDLBP | high density lipoprotein binding protein | -0.0216393 |
| CEP170 | centrosomal protein 170kDa | -0.021088 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0210717 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0209505 |
| ZNF292 | zinc finger protein 292 | -0.020902 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0208783 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0207435 |
| NDRG1 | N-myc downstream regulated 1 | -0.020726 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0206712 |
