| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.157152 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.105008 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0972978 |
| POTEF | POTE ankyrin domain family, member F | 0.0871301 |
| NDRG1 | N-myc downstream regulated 1 | 0.0777918 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0775944 |
| TGM2 | transglutaminase 2 | 0.0726255 |
| MCL1 | myeloid cell leukemia 1 | 0.071936 |
| EGFR | epidermal growth factor receptor | 0.0718223 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0682098 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0679771 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0644317 |
| EFNA5 | ephrin-A5 | 0.0633093 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0615823 |
| TRRAP | transformation/transcription domain-associated protein | 0.0612686 |
| LDHA | lactate dehydrogenase A | 0.047781 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0470696 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0468407 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0461824 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0457109 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0445013 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.043495 |
| BCL2L1 | BCL2-like 1 | 0.0428354 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.041254 |
| MYADM | myeloid-associated differentiation marker | 0.039725 |
| SGMS2 | sphingomyelin synthase 2 | 0.0376548 |
| PGK1 | phosphoglycerate kinase 1 | 0.0367775 |
| CCNL1 | cyclin L1 | 0.0361167 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0344129 |
| HMGA1 | high mobility group AT-hook 1 | 0.0339714 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0335428 |
| CD68 | CD68 molecule | 0.0335307 |
| RPS2 | ribosomal protein S2 | 0.0333117 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0319739 |
| EPHA2 | EPH receptor A2 | 0.0307865 |
| NUP98 | nucleoporin 98kDa | 0.0298385 |
| EFNB2 | ephrin-B2 | 0.0297561 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0287843 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0286837 |
| FLNA | filamin A, alpha | 0.0286396 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0283934 |
| MYO1E | myosin IE | 0.0281929 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0280942 |
| RPL9 | ribosomal protein L9 | 0.0277976 |
| TXNIP | thioredoxin interacting protein | 0.0276576 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0272477 |
| HMGA2 | high mobility group AT-hook 2 | 0.0269423 |
| RPS26 | ribosomal protein S26 | 0.0265667 |
| FOXO1 | forkhead box O1 | 0.026372 |
| FLNB | filamin B, beta | 0.0260165 |
| BMP6 | bone morphogenetic protein 6 | 0.0260074 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0255671 |
| WWC1 | WW and C2 domain containing 1 | 0.0255554 |
| ANXA5 | annexin A5 | 0.0251617 |
| OSMR | oncostatin M receptor | 0.0247663 |
| MSN | moesin | 0.0245966 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0236622 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0236387 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0235039 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0230097 |
| TJP1 | tight junction protein 1 | 0.0229985 |
| SMAD3 | SMAD family member 3 | 0.0229093 |
| PKM | pyruvate kinase, muscle | 0.0226798 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0226489 |
| SEPTIN9 | septin 9 | 0.022632 |
| RPS27 | ribosomal protein S27 | 0.0225019 |
| LCN2 | lipocalin 2 | 0.0224725 |
| EGR1 | early growth response 1 | 0.0222559 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0220328 |
| NUP58 | nucleoporin 58 | 0.0217322 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0216539 |
| CTSB | cathepsin B | 0.0216367 |
| PLS3 | plastin 3 | 0.0216112 |
| SBDS | Shwachman-Bodian-Diamond syndrome | 0.0215292 |
| BRD2 | bromodomain containing 2 | 0.021277 |
| RUNX1 | runt-related transcription factor 1 | 0.0212076 |
| PLEC | plectin | 0.0209041 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0208959 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0207577 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0206553 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0205585 |
| TGFA | transforming growth factor, alpha | 0.0205316 |
| HLA-A | major histocompatibility complex, class I, A | 0.0203703 |
| PXDN | peroxidasin | 0.0203695 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0202325 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0202101 |
| KLHDC10 | kelch domain containing 10 | 0.0201472 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0199299 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.019736 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.019517 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0195126 |
| FHL2 | four and a half LIM domains 2 | 0.0192138 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0191571 |
| MXD1 | MAX dimerization protein 1 | 0.0188805 |
| ATXN2L | ataxin 2-like | 0.018504 |
| FOSL2 | FOS-like antigen 2 | 0.0183496 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0181632 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0180753 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.018069 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0180137 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.289107 |
| PTMA | prothymosin, alpha | -0.171042 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.130288 |
| AHNAK | AHNAK nucleoprotein | -0.129 |
| ASPH | aspartate beta-hydroxylase | -0.102697 |
| VIM | vimentin | -0.0995838 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0989416 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0945488 |
| VCAN | versican | -0.0895642 |
| LMO7 | LIM domain 7 | -0.0874006 |
| TXNRD1 | thioredoxin reductase 1 | -0.0856505 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0815496 |
| ITGA6 | integrin, alpha 6 | -0.0812355 |
| S100A10 | S100 calcium binding protein A10 | -0.0783274 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0739524 |
| EZR | ezrin | -0.0694985 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0667358 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.062776 |
| CD2AP | CD2-associated protein | -0.0594436 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0558699 |
| DSG2 | desmoglein 2 | -0.0515729 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0501763 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0500241 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0499697 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0490681 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0488911 |
| OGA | O-GlcNAcase | -0.0488211 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0483205 |
| DIAPH2 | diaphanous-related formin 2 | -0.0467212 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0466461 |
| SQSTM1 | sequestosome 1 | -0.0466086 |
| S100A4 | S100 calcium binding protein A4 | -0.0462812 |
| IER3 | immediate early response 3 | -0.0447894 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0447439 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0433484 |
| PERP | PERP, TP53 apoptosis effector | -0.042903 |
| FTL | ferritin, light polypeptide | -0.0427818 |
| STK39 | serine threonine kinase 39 | -0.0423065 |
| KLF6 | Kruppel-like factor 6 | -0.0421673 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0419752 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0419502 |
| NPSR1 | neuropeptide S receptor 1 | -0.0418317 |
| RPL31 | ribosomal protein L31 | -0.0414113 |
| EPCAM | epithelial cell adhesion molecule | -0.0403556 |
| ARF4 | ADP-ribosylation factor 4 | -0.0400174 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.039545 |
| DSPP | dentin sialophosphoprotein | -0.0383491 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.038087 |
| SBF2 | SET binding factor 2 | -0.0375834 |
| ZNF292 | zinc finger protein 292 | -0.0370304 |
| RPS24 | ribosomal protein S24 | -0.0362127 |
| JMJD1C | jumonji domain containing 1C | -0.0361323 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0359937 |
| RBM39 | RNA binding motif protein 39 | -0.0351898 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0349989 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0349177 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0348257 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0345794 |
| EMP1 | epithelial membrane protein 1 | -0.0342502 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0342291 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0339783 |
| GOLGA4 | golgin A4 | -0.033302 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0330686 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0329874 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.03274 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0326414 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0322491 |
| SLMAP | sarcolemma associated protein | -0.0322454 |
| NEK7 | NIMA-related kinase 7 | -0.0319816 |
| ANLN | anillin, actin binding protein | -0.031888 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0314221 |
| FAM107B | family with sequence similarity 107, member B | -0.0310586 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0308689 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0307414 |
| TMSB4X | thymosin beta 4, X-linked | -0.0306915 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0299419 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0298224 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0297718 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0297512 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0295062 |
| FERMT1 | fermitin family member 1 | -0.0293045 |
| RIOK3 | RIO kinase 3 | -0.0291487 |
| RPS12 | ribosomal protein S12 | -0.0290564 |
| KRT18 | keratin 18, type I | -0.0287488 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0286853 |
| LYZ | lysozyme | -0.0285687 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0283978 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0283609 |
| DST | dystonin | -0.0283444 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0281388 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0281101 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0280565 |
| MATR3 | matrin 3 | -0.0279412 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0279337 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0276803 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0276382 |
| MYO6 | myosin VI | -0.0273446 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0271617 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0270461 |
| NBEAL1 | neurobeachin-like 1 | -0.0268555 |
