| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.17779 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.142459 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.142184 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.115957 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.109755 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.108197 |
| TOX | thymocyte selection-associated high mobility group box | 0.102969 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0742581 |
| PKM | pyruvate kinase, muscle | 0.0657753 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0614386 |
| ZNF608 | zinc finger protein 608 | 0.0592807 |
| MKI67 | marker of proliferation Ki-67 | 0.0586742 |
| CENPF | centromere protein F, 350/400kDa | 0.0580661 |
| PGK1 | phosphoglycerate kinase 1 | 0.0574541 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0550645 |
| JMJD1C | jumonji domain containing 1C | 0.0515211 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0512961 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.049947 |
| CDH18 | cadherin 18, type 2 | 0.0482858 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.047688 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0474696 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0472576 |
| WLS | wntless Wnt ligand secretion mediator | 0.047163 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0467802 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0441339 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0440707 |
| MATR3 | matrin 3 | 0.0437687 |
| LDHB | lactate dehydrogenase B | 0.0415034 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0387478 |
| RHOA | ras homolog family member A | 0.0386214 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0383915 |
| XPO1 | exportin 1 | 0.0374293 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0371427 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0365236 |
| SHROOM3 | shroom family member 3 | 0.0363428 |
| FLNA | filamin A, alpha | 0.0362244 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0359579 |
| POTEF | POTE ankyrin domain family, member F | 0.0358466 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0353146 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0352256 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0350103 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0347668 |
| TBC1D5 | TBC1 domain family, member 5 | 0.034567 |
| KIF5B | kinesin family member 5B | 0.033937 |
| ENO1 | enolase 1, (alpha) | 0.0331528 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0327281 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0323796 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0323772 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0323542 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0322143 |
| EXOC6B | exocyst complex component 6B | 0.0321743 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.032022 |
| CENPE | centromere protein E, 312kDa | 0.0319614 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.031925 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0318865 |
| PHF21A | PHD finger protein 21A | 0.031541 |
| DST | dystonin | 0.0314754 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0312277 |
| BNC2 | basonuclin 2 | 0.0308008 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0307248 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.030708 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0304325 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0303708 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0301205 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0300571 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0300561 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | 0.0299053 |
| TMX3 | thioredoxin-related transmembrane protein 3 | 0.0295929 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0295782 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0293646 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0292548 |
| RPL4 | ribosomal protein L4 | 0.0292052 |
| SFPQ | splicing factor proline/glutamine-rich | 0.028811 |
| NFIB | nuclear factor I/B | 0.0287241 |
| NFIA | nuclear factor I/A | 0.0286583 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0282741 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0281513 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.027812 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0277762 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0276393 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0275499 |
| CCNL1 | cyclin L1 | 0.0275219 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0274813 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0274716 |
| NUP58 | nucleoporin 58 | 0.027383 |
| NONO | non-POU domain containing, octamer-binding | 0.0273649 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0269246 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0268693 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0268591 |
| NRDC | nardilysin convertase | 0.0268549 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0268511 |
| ACTG1 | actin gamma 1 | 0.0266439 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0265979 |
| ERBIN | erbb2 interacting protein | 0.0262894 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0260443 |
| MAGEA4 | melanoma antigen family A4 | 0.0260183 |
| USP32 | ubiquitin specific peptidase 32 | 0.0258204 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0257674 |
| NBEAL1 | neurobeachin-like 1 | 0.025676 |
| SMAD9 | SMAD family member 9 | 0.0256258 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPAS3 | neuronal PAS domain protein 3 | -0.132148 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0879827 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0731738 |
| RCC1 | regulator of chromosome condensation 1 | -0.0694285 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0648593 |
| RPS24 | ribosomal protein S24 | -0.0619434 |
| NEBL | nebulette | -0.0572637 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0572257 |
| RPS8 | ribosomal protein S8 | -0.0555351 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.055124 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0515279 |
| TENM3 | teneurin transmembrane protein 3 | -0.049808 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0497601 |
| TMSB10 | thymosin beta 10 | -0.0472361 |
| RPS21 | ribosomal protein S21 | -0.0466576 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0448824 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0448436 |
| MT2A | metallothionein 2A | -0.0447823 |
| FMNL2 | formin-like 2 | -0.0438178 |
| RPL31 | ribosomal protein L31 | -0.0436213 |
| RPL23 | ribosomal protein L23 | -0.0431218 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0430738 |
| RPL34 | ribosomal protein L34 | -0.0424072 |
| SMYD3 | SET and MYND domain containing 3 | -0.0423239 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.040481 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0400008 |
| PTMA | prothymosin, alpha | -0.0399561 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0391919 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0382308 |
| RPS27A | ribosomal protein S27a | -0.0382201 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.038206 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0353597 |
| RPLP2 | ribosomal protein, large, P2 | -0.0352809 |
| MSH4 | mutS homolog 4 | -0.0344846 |
| UBE3C | ubiquitin protein ligase E3C | -0.0341027 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0339745 |
| PARD3 | par-3 family cell polarity regulator | -0.0337761 |
| RPL26 | ribosomal protein L26 | -0.0331194 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0317839 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0316504 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0315905 |
| RPL37 | ribosomal protein L37 | -0.0305652 |
| SBF2 | SET binding factor 2 | -0.0299595 |
| SNX14 | sorting nexin 14 | -0.0299319 |
| ZNF217 | zinc finger protein 217 | -0.0297245 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0295069 |
| ATP9A | ATPase, class II, type 9A | -0.029075 |
| RPS29 | ribosomal protein S29 | -0.0280024 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0273762 |
| ATM | ATM serine/threonine kinase | -0.0272312 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0271063 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0268253 |
| RPL12 | ribosomal protein L12 | -0.0266104 |
| NOP58 | NOP58 ribonucleoprotein | -0.0262973 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0261429 |
| CCDC138 | coiled-coil domain containing 138 | -0.0251068 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0250676 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0249802 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0247455 |
| DENND1A | DENN/MADD domain containing 1A | -0.0243831 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0241911 |
| DIAPH2 | diaphanous-related formin 2 | -0.0241282 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0239705 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0239138 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0237357 |
| RPL9 | ribosomal protein L9 | -0.0235008 |
| TMEM178B | transmembrane protein 178B | -0.0233475 |
| RPL36A | ribosomal protein L36a | -0.0233396 |
| RPL11 | ribosomal protein L11 | -0.0232398 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0231897 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0231553 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0230812 |
| RPL32 | ribosomal protein L32 | -0.0230321 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0228742 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0228017 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0226577 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0224003 |
| RPL7A | ribosomal protein L7a | -0.0223392 |
| TMEM14B | transmembrane protein 14B | -0.0221466 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0220587 |
| ZNF407 | zinc finger protein 407 | -0.0214656 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0213683 |
| RPS16 | ribosomal protein S16 | -0.0212083 |
| HLA-B | major histocompatibility complex, class I, B | -0.0211713 |
| LRRC23 | leucine rich repeat containing 23 | -0.0210618 |
| EGFR | epidermal growth factor receptor | -0.0209791 |
| RPS19 | ribosomal protein S19 | -0.0208637 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0208007 |
| CFDP1 | craniofacial development protein 1 | -0.0207428 |
| PRELID2 | PRELI domain containing 2 | -0.0204656 |
| RRBP1 | ribosome binding protein 1 | -0.0203846 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.020303 |
| RPL5 | ribosomal protein L5 | -0.0201572 |
| RPL28 | ribosomal protein L28 | -0.0200739 |
| RPS15 | ribosomal protein S15 | -0.020069 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.01991 |
| CCDC47 | coiled-coil domain containing 47 | -0.0197 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0195089 |
| SAFB2 | scaffold attachment factor B2 | -0.0194747 |
| STX8 | syntaxin 8 | -0.0192644 |
