| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.342709 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.111321 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0927141 |
| ACTG1 | actin gamma 1 | 0.0917251 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0769378 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.07097 |
| EGR1 | early growth response 1 | 0.0685237 |
| LDHA | lactate dehydrogenase A | 0.0650952 |
| VGF | VGF nerve growth factor inducible | 0.0565351 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0558343 |
| CD109 | CD109 molecule | 0.0544609 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0505783 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0487349 |
| PKM | pyruvate kinase, muscle | 0.0486269 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0484102 |
| NLGN1 | neuroligin 1 | 0.0477396 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0468546 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0461954 |
| TNNC1 | troponin C type 1 (slow) | 0.0440426 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0437767 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0425938 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.040684 |
| PGK1 | phosphoglycerate kinase 1 | 0.0404739 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0392812 |
| SFTPA2 | surfactant protein A2 | 0.0388191 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0384222 |
| ICAM1 | intercellular adhesion molecule 1 | 0.037174 |
| RNF213 | ring finger protein 213 | 0.0370227 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0363592 |
| ENO1 | enolase 1, (alpha) | 0.0355776 |
| ASPH | aspartate beta-hydroxylase | 0.0355391 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0352551 |
| ARFGEF3 | ARFGEF family member 3 | 0.0352499 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0347372 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0346211 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0344338 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0338252 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0337754 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0332256 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0326489 |
| FLNA | filamin A, alpha | 0.0325177 |
| FLNB | filamin B, beta | 0.0322598 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.032002 |
| MCL1 | myeloid cell leukemia 1 | 0.0316189 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0299242 |
| GANAB | glucosidase, alpha; neutral AB | 0.0294589 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0293603 |
| EFR3B | EFR3 homolog B (S. cerevisiae) | 0.0292233 |
| RCAN1 | regulator of calcineurin 1 | 0.0287472 |
| PI15 | peptidase inhibitor 15 | 0.0286563 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0284256 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0281075 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0278726 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0270274 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0269951 |
| CDH19 | cadherin 19, type 2 | 0.026819 |
| KLF10 | Kruppel-like factor 10 | 0.026723 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0266342 |
| TMEM255B | transmembrane protein 255B | 0.0255311 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0252721 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.025246 |
| STRIP2 | striatin interacting protein 2 | 0.0250787 |
| ITGB8 | integrin, beta 8 | 0.0246688 |
| CYGB | cytoglobin | 0.0242479 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0242321 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0238818 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0237547 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0236517 |
| TRRAP | transformation/transcription domain-associated protein | 0.0234963 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0234177 |
| NOTCH2 | notch 2 | 0.0234101 |
| HMGA1 | high mobility group AT-hook 1 | 0.023249 |
| USP34 | ubiquitin specific peptidase 34 | 0.0227833 |
| CDK16 | cyclin-dependent kinase 16 | 0.0227476 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0227284 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0226013 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0225475 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0222951 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0222779 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0221351 |
| CTSB | cathepsin B | 0.0219612 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0216076 |
| TRIM9 | tripartite motif containing 9 | 0.0215973 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0212358 |
| NRP2 | neuropilin 2 | 0.0211886 |
| ACTN1 | actinin, alpha 1 | 0.0211684 |
| SETBP1 | SET binding protein 1 | 0.0210896 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0205601 |
| SLK | STE20-like kinase | 0.0204786 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0204585 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0203084 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0199174 |
| OSMR | oncostatin M receptor | 0.0195978 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0195571 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0194873 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0194369 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0193098 |
| PFKL | phosphofructokinase, liver | 0.019264 |
| JAK1 | Janus kinase 1 | 0.0191752 |
| PLXNB2 | plexin B2 | 0.0188557 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.187866 |
| VIM | vimentin | -0.126138 |
| TMSB10 | thymosin beta 10 | -0.110931 |
| FMN1 | formin 1 | -0.0837 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0781188 |
| INSIG1 | insulin induced gene 1 | -0.0758813 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0744861 |
| HMCN1 | hemicentin 1 | -0.0718378 |
| PTMA | prothymosin, alpha | -0.0717837 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0649988 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0645507 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0632024 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0620234 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0592015 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0591336 |
| DCT | dopachrome tautomerase | -0.0585703 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0551625 |
| CALU | calumenin | -0.0540821 |
| NAV3 | neuron navigator 3 | -0.0536237 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.05275 |
| AHNAK | AHNAK nucleoprotein | -0.0518961 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0511091 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0506887 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.050111 |
| RNF145 | ring finger protein 145 | -0.0496073 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0463388 |
| FRMD5 | FERM domain containing 5 | -0.0446132 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0441248 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0436572 |
| PHF21A | PHD finger protein 21A | -0.0435817 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0426637 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0418631 |
| IER3 | immediate early response 3 | -0.0415851 |
| YBX1 | Y box binding protein 1 | -0.0408825 |
| GNAS | GNAS complex locus | -0.0408129 |
| S100A6 | S100 calcium binding protein A6 | -0.0404273 |
| SRPK2 | SRSF protein kinase 2 | -0.0397271 |
| CDC73 | cell division cycle 73 | -0.0393167 |
| MACROD2 | MACRO domain containing 2 | -0.0392091 |
| NHSL1 | NHS-like 1 | -0.0385063 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0383715 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0382917 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0379781 |
| EHBP1 | EH domain binding protein 1 | -0.0376808 |
| CANX | calnexin | -0.0370595 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.036543 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0365283 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0362316 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0360826 |
| WDR45B | WD repeat domain 45B | -0.035423 |
| BBX | bobby sox homolog (Drosophila) | -0.035362 |
| CUX1 | cut-like homeobox 1 | -0.0351545 |
| TFG | TRK-fused gene | -0.0350427 |
| HELZ | helicase with zinc finger | -0.0346204 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0343528 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0341293 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0328856 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0327527 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0318621 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0314744 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0314527 |
| FTL | ferritin, light polypeptide | -0.0313688 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | -0.0311324 |
| LSAMP | limbic system-associated membrane protein | -0.0308186 |
| NRCAM | neuronal cell adhesion molecule | -0.0307215 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0304927 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0304355 |
| CENPF | centromere protein F, 350/400kDa | -0.0302248 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0302151 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) | -0.030055 |
| RNF24 | ring finger protein 24 | -0.0295917 |
| NPR2 | natriuretic peptide receptor 2 | -0.0293697 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0292269 |
| RFX7 | regulatory factor X, 7 | -0.0287294 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0285728 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0282034 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.028065 |
| BNC2 | basonuclin 2 | -0.0280519 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0279623 |
| RPL37A | ribosomal protein L37a | -0.0275126 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0274134 |
| S100A9 | S100 calcium binding protein A9 | -0.0273817 |
| JAZF1 | JAZF zinc finger 1 | -0.0273575 |
| S100A10 | S100 calcium binding protein A10 | -0.0268793 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0268697 |
| TOP1 | topoisomerase (DNA) I | -0.0268484 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0268223 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0263304 |
| SNX14 | sorting nexin 14 | -0.026177 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | -0.0261114 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0258114 |
| NEK7 | NIMA-related kinase 7 | -0.0257675 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0256825 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0256475 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0256433 |
| OGA | O-GlcNAcase | -0.0254998 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0252359 |
| RHEB | Ras homolog enriched in brain | -0.0251577 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0250507 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0249915 |
