| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGM2 | transglutaminase 2 | 0.141692 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.135179 |
| KRT19 | keratin 19, type I | 0.102643 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0917011 |
| CP | ceruloplasmin (ferroxidase) | 0.0869115 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0866724 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0841659 |
| EFNA5 | ephrin-A5 | 0.0693392 |
| PKM | pyruvate kinase, muscle | 0.0690684 |
| MCL1 | myeloid cell leukemia 1 | 0.0687164 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0637698 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0628933 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0622484 |
| APOL1 | apolipoprotein L, 1 | 0.0609228 |
| SMAD3 | SMAD family member 3 | 0.0606646 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.059368 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0581199 |
| C3 | complement component 3 | 0.056463 |
| B2M | beta-2-microglobulin | 0.0559752 |
| LCN2 | lipocalin 2 | 0.055208 |
| RAD51B | RAD51 paralog B | 0.0546479 |
| HLA-B | major histocompatibility complex, class I, B | 0.0511682 |
| RNF213 | ring finger protein 213 | 0.0498214 |
| MUC16 | mucin 16, cell surface associated | 0.0490769 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0488122 |
| LAMB3 | laminin, beta 3 | 0.0480671 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0478797 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.047101 |
| PGK1 | phosphoglycerate kinase 1 | 0.0464241 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0459152 |
| HLA-A | major histocompatibility complex, class I, A | 0.0458372 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0443878 |
| EGR1 | early growth response 1 | 0.0433072 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0423555 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0415628 |
| PLAT | plasminogen activator, tissue | 0.0396586 |
| MUC4 | mucin 4, cell surface associated | 0.0392062 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.039 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0385505 |
| LDHA | lactate dehydrogenase A | 0.0369812 |
| CD68 | CD68 molecule | 0.0367633 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0366923 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0363333 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0363004 |
| EGFR | epidermal growth factor receptor | 0.0351175 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0349549 |
| MT2A | metallothionein 2A | 0.0340142 |
| ITGB4 | integrin, beta 4 | 0.0339385 |
| SFTPA2 | surfactant protein A2 | 0.0339072 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0334644 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0334288 |
| TMC5 | transmembrane channel-like 5 | 0.0329283 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0328173 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0327772 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0324799 |
| JUP | junction plakoglobin | 0.0317336 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0314329 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0311895 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0310932 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.030868 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0306534 |
| NDRG1 | N-myc downstream regulated 1 | 0.0303702 |
| MX2 | MX dynamin-like GTPase 2 | 0.0300629 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0299485 |
| CMIP | c-Maf inducing protein | 0.029304 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0284829 |
| MX1 | MX dynamin-like GTPase 1 | 0.0282673 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0282553 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0280753 |
| MXD1 | MAX dimerization protein 1 | 0.0275461 |
| MYADM | myeloid-associated differentiation marker | 0.0275267 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0271882 |
| CFB | complement factor B | 0.0271335 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0269361 |
| ATXN1 | ataxin 1 | 0.0262816 |
| PLEC | plectin | 0.0260644 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0255672 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0252965 |
| AGRN | agrin | 0.0252383 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0251763 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0245888 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0245235 |
| MT1E | metallothionein 1E | 0.0244213 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0241152 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0240114 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0234814 |
| PADI1 | peptidyl arginine deiminase, type I | 0.023303 |
| ANXA4 | annexin A4 | 0.0231704 |
| TNS4 | tensin 4 | 0.0231294 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0230592 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0229446 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0226548 |
| DUSP5 | dual specificity phosphatase 5 | 0.0223557 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0222308 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0222097 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0219781 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0218906 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0217428 |
| IGF2 | insulin-like growth factor 2 | 0.021471 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.0212143 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.236713 |
| PTMA | prothymosin, alpha | -0.188628 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.137127 |
| ASPH | aspartate beta-hydroxylase | -0.135525 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.119346 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.11648 |
| TMSB4X | thymosin beta 4, X-linked | -0.108903 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.107601 |
| RBM39 | RNA binding motif protein 39 | -0.0830985 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0815288 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0782887 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0777963 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0775595 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0767254 |
| SPAG9 | sperm associated antigen 9 | -0.0764495 |
| VIM | vimentin | -0.0763463 |
| AHNAK | AHNAK nucleoprotein | -0.0699528 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0693479 |
| MMP7 | matrix metallopeptidase 7 | -0.0670208 |
| FTL | ferritin, light polypeptide | -0.0668285 |
| RTN4 | reticulon 4 | -0.0632521 |
| RPL19 | ribosomal protein L19 | -0.0624774 |
| PLAU | plasminogen activator, urokinase | -0.0614381 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0592209 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.059184 |
| MT1X | metallothionein 1X | -0.0587153 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0578219 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0561829 |
| CANX | calnexin | -0.0550871 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.054803 |
| OGA | O-GlcNAcase | -0.0548004 |
| CD2AP | CD2-associated protein | -0.0539737 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.052987 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0526799 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0524449 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.052397 |
| ANXA2 | annexin A2 | -0.0514058 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0480316 |
| RLF | rearranged L-myc fusion | -0.0479513 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0478526 |
| DST | dystonin | -0.0467234 |
| IER3 | immediate early response 3 | -0.0465089 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0464611 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0458043 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0457415 |
| KLF6 | Kruppel-like factor 6 | -0.0447273 |
| YBX1 | Y box binding protein 1 | -0.0438367 |
| EZR | ezrin | -0.0434415 |
| JMJD1C | jumonji domain containing 1C | -0.0431925 |
| MEF2A | myocyte enhancer factor 2A | -0.0430187 |
| TOP1 | topoisomerase (DNA) I | -0.0427284 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0424308 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0422138 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0415172 |
| EREG | epiregulin | -0.0407052 |
| FAM162A | family with sequence similarity 162, member A | -0.0402956 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0402269 |
| ZNF292 | zinc finger protein 292 | -0.0389847 |
| UBC | ubiquitin C | -0.0389834 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.038917 |
| LAMC2 | laminin, gamma 2 | -0.0386642 |
| TFG | TRK-fused gene | -0.0384699 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0384291 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0378577 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0377152 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0373709 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.037171 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 | -0.0371297 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0366916 |
| ABI1 | abl-interactor 1 | -0.0366131 |
| RPS24 | ribosomal protein S24 | -0.0363228 |
| CDC73 | cell division cycle 73 | -0.0362562 |
| GNAS | GNAS complex locus | -0.0361325 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0359007 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0355596 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0350432 |
| RPS3 | ribosomal protein S3 | -0.0342471 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0339028 |
| LMO7 | LIM domain 7 | -0.0338636 |
| VCL | vinculin | -0.0337881 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0336285 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0334921 |
| TMEM263 | transmembrane protein 263 | -0.0334582 |
| MAP1B | microtubule-associated protein 1B | -0.0334384 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0333282 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0330449 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0329887 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0329034 |
| RPLP1 | ribosomal protein, large, P1 | -0.0326239 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0324529 |
| TXNRD1 | thioredoxin reductase 1 | -0.032429 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0322742 |
| RPL5 | ribosomal protein L5 | -0.0321533 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0321514 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0312849 |
| CCDC47 | coiled-coil domain containing 47 | -0.0311861 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0311565 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0311155 |
| QKI | QKI, KH domain containing, RNA binding | -0.0310504 |
| MATR3 | matrin 3 | -0.031049 |
