| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.102565 |
| IGF2 | insulin-like growth factor 2 | 0.083881 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0763353 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0712159 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0711886 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0681471 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0665865 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0597332 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0594103 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0582432 |
| PCBP3 | poly(rC) binding protein 3 | 0.0574245 |
| MSI2 | musashi RNA-binding protein 2 | 0.0561179 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0509812 |
| EXOC4 | exocyst complex component 4 | 0.0492768 |
| NRG1 | neuregulin 1 | 0.0472947 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0462264 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0453606 |
| HIP1 | huntingtin interacting protein 1 | 0.0440777 |
| UNC5B | unc-5 homolog B (C. elegans) | 0.0440689 |
| PRRC2C | proline-rich coiled-coil 2C | 0.042631 |
| RGS5 | regulator of G-protein signaling 5 | 0.0414398 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0413025 |
| FAM13A | family with sequence similarity 13, member A | 0.0408778 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0400084 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0396087 |
| MED13L | mediator complex subunit 13-like | 0.039103 |
| AHR | aryl hydrocarbon receptor | 0.0389509 |
| RNF213 | ring finger protein 213 | 0.0385361 |
| CREBBP | CREB binding protein | 0.0382078 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0379046 |
| RIGI | RNA sensor RIG-I | 0.0378147 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.037489 |
| SIK2 | salt-inducible kinase 2 | 0.0363401 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0360881 |
| TRIM24 | tripartite motif containing 24 | 0.0350736 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0349485 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0348446 |
| CUX1 | cut-like homeobox 1 | 0.0347576 |
| RNF150 | ring finger protein 150 | 0.0347256 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0346934 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0346619 |
| PCNX2 | pecanex 2 | 0.0344973 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0343093 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0338223 |
| MX1 | MX dynamin-like GTPase 1 | 0.0337382 |
| RAD51B | RAD51 paralog B | 0.0333006 |
| NRP1 | neuropilin 1 | 0.0332227 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0331106 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0323422 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0319299 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0318646 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0317307 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0316475 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0315292 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0313853 |
| MED13 | mediator complex subunit 13 | 0.0310124 |
| HAS2 | hyaluronan synthase 2 | 0.030675 |
| CTSB | cathepsin B | 0.0298553 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0294851 |
| GATA3 | GATA binding protein 3 | 0.0291522 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0289886 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0288656 |
| TENM4 | teneurin transmembrane protein 4 | 0.0284613 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0283864 |
| MEF2A | myocyte enhancer factor 2A | 0.0283624 |
| PLAT | plasminogen activator, tissue | 0.0280999 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0278648 |
| RUNX1 | runt-related transcription factor 1 | 0.0277893 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0277173 |
| RGS4 | regulator of G-protein signaling 4 | 0.0274258 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0274249 |
| ARRDC3 | arrestin domain containing 3 | 0.0271087 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0270743 |
| KLF9 | Kruppel-like factor 9 | 0.0268742 |
| ACTN1 | actinin, alpha 1 | 0.0267607 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0267562 |
| DNMBP | dynamin binding protein | 0.0265018 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0264319 |
| SMYD3 | SET and MYND domain containing 3 | 0.02643 |
| DTNA | dystrobrevin, alpha | 0.0263692 |
| TRIM25 | tripartite motif containing 25 | 0.0263497 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0256958 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0255915 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0249894 |
| THBS1 | thrombospondin 1 | 0.0249338 |
| PHF3 | PHD finger protein 3 | 0.0247591 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0247046 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0246126 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0245641 |
| RARA | retinoic acid receptor, alpha | 0.0245535 |
| RNF144A | ring finger protein 144A | 0.0244478 |
| EGFR | epidermal growth factor receptor | 0.0243847 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0240877 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0240763 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0240172 |
| TUT4 | terminal uridylyl transferase 4 | 0.0238645 |
| SFTPA2 | surfactant protein A2 | 0.0238444 |
| RET | ret proto-oncogene | 0.023717 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0236494 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0233699 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.220649 |
| PTMA | prothymosin, alpha | -0.0969098 |
| MAP1B | microtubule-associated protein 1B | -0.0651377 |
| VIM | vimentin | -0.0624934 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0596652 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0553642 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0553358 |
| VCL | vinculin | -0.0540396 |
| TMSB10 | thymosin beta 10 | -0.0489388 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0479142 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0450529 |
| COL3A1 | collagen, type III, alpha 1 | -0.0433964 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0433396 |
| CENPF | centromere protein F, 350/400kDa | -0.0421777 |
| RPL38 | ribosomal protein L38 | -0.0399874 |
| RPS24 | ribosomal protein S24 | -0.0396486 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0375704 |
| RPL31 | ribosomal protein L31 | -0.0370293 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.036428 |
| COL1A1 | collagen, type I, alpha 1 | -0.0360309 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0341521 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0338101 |
| SYT1 | synaptotagmin I | -0.033704 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0332396 |
| GPC5 | glypican 5 | -0.0322007 |
| S100A6 | S100 calcium binding protein A6 | -0.0315223 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0313663 |
| RPL19 | ribosomal protein L19 | -0.0308891 |
| DSTN | destrin (actin depolymerizing factor) | -0.0305115 |
| TMEM87A | transmembrane protein 87A | -0.030229 |
| RPL5 | ribosomal protein L5 | -0.0299555 |
| NREP | neuronal regeneration related protein | -0.0296344 |
| ZNF609 | zinc finger protein 609 | -0.029541 |
| TRIB2 | tribbles pseudokinase 2 | -0.0293682 |
| RPS6 | ribosomal protein S6 | -0.0290959 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0283342 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0278451 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0277802 |
| WDR45B | WD repeat domain 45B | -0.0274651 |
| AHNAK | AHNAK nucleoprotein | -0.0264137 |
| MT2A | metallothionein 2A | -0.0261433 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0258966 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0257749 |
| GLG1 | golgi glycoprotein 1 | -0.0257186 |
| TPM4 | tropomyosin 4 | -0.0253695 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0253395 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0252852 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0252506 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0251219 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0250732 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0247782 |
| YY1 | YY1 transcription factor | -0.0246793 |
| BRD4 | bromodomain containing 4 | -0.0246506 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0239498 |
| OSBPL1A | oxysterol binding protein-like 1A | -0.0239183 |
| TLK2 | tousled-like kinase 2 | -0.0238923 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0237657 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0237479 |
| GOLGA4 | golgin A4 | -0.0236866 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0235266 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0234195 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0230577 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0229038 |
| RPLP2 | ribosomal protein, large, P2 | -0.0227332 |
| DST | dystonin | -0.0218991 |
| RPS5 | ribosomal protein S5 | -0.0218806 |
| AEBP2 | AE binding protein 2 | -0.0218786 |
| USP34 | ubiquitin specific peptidase 34 | -0.0217023 |
| SEPTIN9 | septin 9 | -0.0215073 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0213736 |
| SUCO | SUN domain containing ossification factor | -0.021358 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0213464 |
| RPL26 | ribosomal protein L26 | -0.0212746 |
| RACK1 | receptor for activated C kinase 1 | -0.0212347 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.021176 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0211545 |
| FMNL2 | formin-like 2 | -0.0207059 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0206977 |
| FOXK2 | forkhead box K2 | -0.0206969 |
| RPS23 | ribosomal protein S23 | -0.0205152 |
| CCDC57 | coiled-coil domain containing 57 | -0.0204573 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.020384 |
| SRPK2 | SRSF protein kinase 2 | -0.0202935 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.0202575 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0201154 |
| PHF21A | PHD finger protein 21A | -0.020066 |
| PRR11 | proline rich 11 | -0.0199686 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0199546 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0199463 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0199264 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0199138 |
| INSIG2 | insulin induced gene 2 | -0.0198047 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0196618 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0196576 |
| FRMD4A | FERM domain containing 4A | -0.0195118 |
| LMNA | lamin A/C | -0.0195056 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0195004 |
| FOXP1 | forkhead box P1 | -0.0194081 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0193883 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0193777 |
