| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MACC1 | metastasis associated in colon cancer 1 | 0.0625364 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0596743 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0535434 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0519973 |
| CCNL1 | cyclin L1 | 0.0509936 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0440303 |
| MUC13 | mucin 13, cell surface associated | 0.0432201 |
| CD68 | CD68 molecule | 0.0429622 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0427495 |
| RNF43 | ring finger protein 43 | 0.0424229 |
| ATP10B | ATPase, class V, type 10B | 0.0402665 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0357472 |
| MYO1E | myosin IE | 0.0347234 |
| RUNX1 | runt-related transcription factor 1 | 0.034219 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.03292 |
| STK24 | serine/threonine kinase 24 | 0.0326687 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0316777 |
| TMEM62 | transmembrane protein 62 | 0.0306626 |
| ATP11A | ATPase, class VI, type 11A | 0.0302065 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0292615 |
| ZNRF3 | zinc and ring finger 3 | 0.029096 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0287414 |
| IL20RA | interleukin 20 receptor, alpha | 0.0276234 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0274062 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0270118 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0269205 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0266861 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0264485 |
| AOPEP | aminopeptidase O (putative) | 0.0260425 |
| LCN2 | lipocalin 2 | 0.0258777 |
| LMTK2 | lemur tyrosine kinase 2 | 0.025472 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0253772 |
| UBAC2 | UBA domain containing 2 | 0.0250645 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0237286 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0233649 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0232273 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0231782 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0231196 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0230501 |
| RNF149 | ring finger protein 149 | 0.0215488 |
| YAP1 | Yes-associated protein 1 | 0.0212816 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0211743 |
| TJP2 | tight junction protein 2 | 0.0210297 |
| BCL2L1 | BCL2-like 1 | 0.0205669 |
| OCLN | occludin | 0.0205115 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0202168 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.020214 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0201366 |
| ABHD2 | abhydrolase domain containing 2 | 0.0200927 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0200608 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0197462 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.019301 |
| PRSS3 | protease, serine, 3 | 0.0191196 |
| AFF1 | AF4/FMR2 family, member 1 | 0.019089 |
| ATP9A | ATPase, class II, type 9A | 0.0189333 |
| PDZD8 | PDZ domain containing 8 | 0.0187229 |
| NCOR2 | nuclear receptor corepressor 2 | 0.018721 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0186944 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0184357 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0183427 |
| DNM2 | dynamin 2 | 0.0181428 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0180288 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0179702 |
| BMP4 | bone morphogenetic protein 4 | 0.0179428 |
| ANXA3 | annexin A3 | 0.0178225 |
| SPATA13 | spermatogenesis associated 13 | 0.0177192 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0176712 |
| MEIS2 | Meis homeobox 2 | 0.0176624 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0175755 |
| TMC5 | transmembrane channel-like 5 | 0.0173497 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0173389 |
| DUSP16 | dual specificity phosphatase 16 | 0.0171044 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0169903 |
| ETNK1 | ethanolamine kinase 1 | 0.0169724 |
| PGK1 | phosphoglycerate kinase 1 | 0.0167985 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0166355 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.016544 |
| PTEN | phosphatase and tensin homolog | 0.016503 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0161706 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0161369 |
| CLYBL | citrate lyase beta like | 0.0156809 |
| EPHB2 | EPH receptor B2 | 0.0156481 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0155558 |
| GPX2 | glutathione peroxidase 2 | 0.0155094 |
| RBM47 | RNA binding motif protein 47 | 0.0152724 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0152201 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0151868 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0148082 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.0146089 |
| TOB1 | transducer of ERBB2, 1 | 0.0145016 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0144834 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0143765 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.0143687 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0143644 |
| TMEM51 | transmembrane protein 51 | 0.014325 |
| TBCC | tubulin folding cofactor C | 0.0142755 |
| RBM33 | RNA binding motif protein 33 | 0.0142442 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.014221 |
| YBX3 | Y box binding protein 3 | 0.0141543 |
| MYO10 | myosin X | 0.0141491 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.152145 |
| INTS6 | integrator complex subunit 6 | -0.140666 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.123529 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.117992 |
| PTMA | prothymosin, alpha | -0.11714 |
| RNF213 | ring finger protein 213 | -0.115554 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.113516 |
| SP100 | SP100 nuclear antigen | -0.10669 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102622 |
| B2M | beta-2-microglobulin | -0.101476 |
| LYZ | lysozyme | -0.0972278 |
| ANXA2 | annexin A2 | -0.0893573 |
| RIGI | RNA sensor RIG-I | -0.0867229 |
| LMO7 | LIM domain 7 | -0.0858469 |
| PLSCR2 | phospholipid scramblase 2 | -0.0804326 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.079319 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0790751 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0783572 |
| AREG | amphiregulin | -0.0758547 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.073878 |
| MX1 | MX dynamin-like GTPase 1 | -0.0738328 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0723661 |
| GOLGB1 | golgin B1 | -0.0716914 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0709637 |
| NPSR1 | neuropeptide S receptor 1 | -0.0709111 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.067329 |
| PERP | PERP, TP53 apoptosis effector | -0.0672699 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0653121 |
| SQSTM1 | sequestosome 1 | -0.0640742 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0620577 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0612961 |
| XAF1 | XIAP associated factor 1 | -0.0595182 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0594933 |
| HLA-B | major histocompatibility complex, class I, B | -0.0593311 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0573723 |
| MX2 | MX dynamin-like GTPase 2 | -0.0557378 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0541028 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0517789 |
| ACTG1 | actin gamma 1 | -0.0511715 |
| TMSB10 | thymosin beta 10 | -0.0511024 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0502011 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0495413 |
| EGR1 | early growth response 1 | -0.0493264 |
| MCL1 | myeloid cell leukemia 1 | -0.0476288 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0469865 |
| ASPH | aspartate beta-hydroxylase | -0.0452427 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0443866 |
| RAB7A | RAB7A, member RAS oncogene family | -0.043587 |
| CANX | calnexin | -0.0435788 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0434764 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0433879 |
| EZR | ezrin | -0.0429531 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0429105 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0427823 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0424639 |
| S100A10 | S100 calcium binding protein A10 | -0.0417365 |
| ENO1 | enolase 1, (alpha) | -0.0402456 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0395839 |
| PMP22 | peripheral myelin protein 22 | -0.0391515 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0387839 |
| IER3 | immediate early response 3 | -0.0381731 |
| SETX | senataxin | -0.0376648 |
| SDC4 | syndecan 4 | -0.037176 |
| LAP3 | leucine aminopeptidase 3 | -0.0367882 |
| FTL | ferritin, light polypeptide | -0.0362695 |
| RPL34 | ribosomal protein L34 | -0.034316 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0343063 |
| RPS24 | ribosomal protein S24 | -0.0342738 |
| APOL1 | apolipoprotein L, 1 | -0.0342184 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.033821 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0335178 |
| PLSCR1 | phospholipid scramblase 1 | -0.0334785 |
| HLA-C | major histocompatibility complex, class I, C | -0.0329776 |
| AHNAK | AHNAK nucleoprotein | -0.0329525 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0323036 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0321141 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0318988 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0318159 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0316905 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0316161 |
| RPS6 | ribosomal protein S6 | -0.0315469 |
| FBXO39 | F-box protein 39 | -0.0315318 |
| NABP1 | nucleic acid binding protein 1 | -0.0313704 |
| ABLIM1 | actin binding LIM protein 1 | -0.0313071 |
| RRBP1 | ribosome binding protein 1 | -0.0310459 |
| HDLBP | high density lipoprotein binding protein | -0.0309489 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0308926 |
| LAMA4 | laminin, alpha 4 | -0.0305834 |
| HLA-E | major histocompatibility complex, class I, E | -0.0304347 |
| IRF1 | interferon regulatory factor 1 | -0.0304061 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0303788 |
| RPL35A | ribosomal protein L35a | -0.0303714 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0302962 |
| POU2F2 | POU class 2 homeobox 2 | -0.030212 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0301538 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0297396 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0296237 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0295453 |
| UBC | ubiquitin C | -0.0294527 |
| HM13 | histocompatibility (minor) 13 | -0.0294246 |
