| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.245799 |
| FN1 | fibronectin 1 | 0.147726 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.134577 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.123328 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0976116 |
| LOX | lysyl oxidase | 0.097393 |
| FAM13A | family with sequence similarity 13, member A | 0.0687591 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.065236 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0617312 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0573509 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0409886 |
| LDHA | lactate dehydrogenase A | 0.038849 |
| HELZ | helicase with zinc finger | 0.0365329 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0336412 |
| TNS3 | tensin 3 | 0.0300139 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0284035 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0283963 |
| RNF220 | ring finger protein 220 | 0.0268246 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0263831 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0261801 |
| NAV2 | neuron navigator 2 | 0.02514 |
| HIP1 | huntingtin interacting protein 1 | 0.0248252 |
| ZNF395 | zinc finger protein 395 | 0.0248138 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0239906 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0239582 |
| PKM | pyruvate kinase, muscle | 0.0230146 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0229541 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0228277 |
| CTSB | cathepsin B | 0.0226565 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0216636 |
| FNIP1 | folliculin interacting protein 1 | 0.0213911 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0213757 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0213158 |
| GLIS3 | GLIS family zinc finger 3 | 0.0212383 |
| PRELID2 | PRELI domain containing 2 | 0.0211016 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0210738 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0209755 |
| PFKP | phosphofructokinase, platelet | 0.0203024 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0201924 |
| PHF3 | PHD finger protein 3 | 0.0201364 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0200828 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0200455 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0197317 |
| PGK1 | phosphoglycerate kinase 1 | 0.0196213 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0195854 |
| FLNA | filamin A, alpha | 0.019551 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0188675 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0185888 |
| CCND3 | cyclin D3 | 0.0185235 |
| GANAB | glucosidase, alpha; neutral AB | 0.0182664 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0182158 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0181936 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0180563 |
| MT1X | metallothionein 1X | 0.0178764 |
| MMP12 | matrix metallopeptidase 12 | 0.0178636 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0177497 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0171922 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0170651 |
| MYO1B | myosin IB | 0.0169184 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0168651 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0165397 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0163859 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0160901 |
| INSIG2 | insulin induced gene 2 | 0.0160193 |
| METTL15 | methyltransferase like 15 | 0.0158975 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0156674 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 | 0.0153717 |
| CCDC102B | coiled-coil domain containing 102B | 0.0153314 |
| MEF2A | myocyte enhancer factor 2A | 0.0153018 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0151352 |
| YBX3 | Y box binding protein 3 | 0.0151082 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0150995 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0150413 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0150298 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0150082 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0148826 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0148572 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0148275 |
| SFXN1 | sideroflexin 1 | 0.0148185 |
| MYOF | myoferlin | 0.0148165 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0146354 |
| TGFB1 | transforming growth factor, beta 1 | 0.0143881 |
| ATP13A3 | ATPase type 13A3 | 0.0142885 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0142553 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0142127 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 0.0141582 |
| LOXL2 | lysyl oxidase-like 2 | 0.0140594 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0140234 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0140143 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0140131 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0140055 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | 0.0139573 |
| HMGA2 | high mobility group AT-hook 2 | 0.013864 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.013757 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0137239 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0136014 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.013565 |
| KLF9 | Kruppel-like factor 9 | 0.0135119 |
| ZNF292 | zinc finger protein 292 | 0.0134858 |
| PER1 | period circadian clock 1 | 0.0134615 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.223231 |
| EXT1 | exostosin glycosyltransferase 1 | -0.150535 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.148059 |
| VIM | vimentin | -0.133451 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.122266 |
| ASPH | aspartate beta-hydroxylase | -0.112035 |
| TMSB10 | thymosin beta 10 | -0.11055 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100419 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0965739 |
| HLA-B | major histocompatibility complex, class I, B | -0.0946025 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0738878 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0710953 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0692608 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0682673 |
| NAV3 | neuron navigator 3 | -0.0650476 |
| CD44 | CD44 molecule (Indian blood group) | -0.0642966 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0631722 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.059373 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0563095 |
| TPM4 | tropomyosin 4 | -0.0538482 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0509749 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.050577 |
| AHNAK | AHNAK nucleoprotein | -0.0498898 |
| PRSS23 | protease, serine, 23 | -0.0497586 |
| FTL | ferritin, light polypeptide | -0.048975 |
| CANX | calnexin | -0.0485891 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0474703 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0462148 |
| DST | dystonin | -0.0457209 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0450793 |
| MYLK | myosin light chain kinase | -0.0446666 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0444147 |
| PTMA | prothymosin, alpha | -0.0441144 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0440345 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0434296 |
| CALD1 | caldesmon 1 | -0.0426385 |
| DTNA | dystrobrevin, alpha | -0.0425315 |
| RPS8 | ribosomal protein S8 | -0.0409492 |
| CALU | calumenin | -0.0404461 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0399135 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0397893 |
| JMJD1C | jumonji domain containing 1C | -0.0390331 |
| MAP1B | microtubule-associated protein 1B | -0.0384899 |
| B2M | beta-2-microglobulin | -0.0378368 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0365994 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0345262 |
| MT2A | metallothionein 2A | -0.0343506 |
| RRBP1 | ribosome binding protein 1 | -0.0341257 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0335826 |
| RPS6 | ribosomal protein S6 | -0.0332697 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0328113 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0328022 |
| RIGI | RNA sensor RIG-I | -0.0324581 |
| CADM1 | cell adhesion molecule 1 | -0.0323538 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0322747 |
| MKI67 | marker of proliferation Ki-67 | -0.0321864 |
| PTK2 | protein tyrosine kinase 2 | -0.0321251 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0320155 |
| RPL31 | ribosomal protein L31 | -0.0319156 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0315985 |
| H3-3B | H3.3 histone B | -0.0315653 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.031519 |
| TENM3 | teneurin transmembrane protein 3 | -0.0314934 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.029797 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0295595 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0293807 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0293644 |
| NLGN1 | neuroligin 1 | -0.0291223 |
| ZNF804A | zinc finger protein 804A | -0.0290679 |
| KYNU | kynureninase | -0.0290457 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.029018 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0280766 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0280121 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0279995 |
| CLMP | CXADR-like membrane protein | -0.0277262 |
| MYO10 | myosin X | -0.0276446 |
| RPS24 | ribosomal protein S24 | -0.0273337 |
| BPTF | bromodomain PHD finger transcription factor | -0.0272457 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0271834 |
| NRXN3 | neurexin 3 | -0.0270816 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0269385 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0267902 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0265854 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0265353 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0264319 |
| HLA-A | major histocompatibility complex, class I, A | -0.0264008 |
| TXNRD1 | thioredoxin reductase 1 | -0.026171 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0261247 |
| ATM | ATM serine/threonine kinase | -0.0260858 |
| USP34 | ubiquitin specific peptidase 34 | -0.0258215 |
| LMNA | lamin A/C | -0.0253479 |
| CD63 | CD63 molecule | -0.0251081 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0250407 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0250326 |
| SQSTM1 | sequestosome 1 | -0.0250253 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0249664 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0249612 |
| TPTE | transmembrane phosphatase with tensin homology | -0.0248956 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0246796 |
| CDK14 | cyclin-dependent kinase 14 | -0.0245796 |
