| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.333866 |
| LDHA | lactate dehydrogenase A | 0.0990952 |
| PKM | pyruvate kinase, muscle | 0.0983053 |
| FAT1 | FAT atypical cadherin 1 | 0.0957954 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0931508 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0921177 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.082159 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0763028 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0751579 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0706336 |
| PGK1 | phosphoglycerate kinase 1 | 0.0688138 |
| EGR1 | early growth response 1 | 0.067231 |
| KRT18 | keratin 18, type I | 0.0564386 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.055942 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0516273 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0510646 |
| MKI67 | marker of proliferation Ki-67 | 0.049833 |
| POTEF | POTE ankyrin domain family, member F | 0.0495423 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0494806 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0489018 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0488236 |
| FLNA | filamin A, alpha | 0.0482936 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0469366 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0467866 |
| ENO1 | enolase 1, (alpha) | 0.0467308 |
| KRT8 | keratin 8, type II | 0.0448166 |
| RHOA | ras homolog family member A | 0.0445655 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0434202 |
| TENM3 | teneurin transmembrane protein 3 | 0.0429311 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0429012 |
| KLF6 | Kruppel-like factor 6 | 0.0409885 |
| CCNL1 | cyclin L1 | 0.0402212 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0388893 |
| RPL4 | ribosomal protein L4 | 0.0384315 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0381807 |
| HMGA1 | high mobility group AT-hook 1 | 0.0379363 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0377956 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0375894 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0371177 |
| EZR | ezrin | 0.0370617 |
| DIAPH1 | diaphanous-related formin 1 | 0.0369851 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0367343 |
| LDLR | low density lipoprotein receptor | 0.036617 |
| SFTPA2 | surfactant protein A2 | 0.0364197 |
| KIF5B | kinesin family member 5B | 0.0360377 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0355991 |
| PLEC | plectin | 0.0354547 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0351843 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0345055 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0338605 |
| ANKRD12 | ankyrin repeat domain 12 | 0.033539 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0332507 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0330759 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.0324811 |
| ACTN4 | actinin, alpha 4 | 0.0322902 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.03133 |
| KRT19 | keratin 19, type I | 0.0308436 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0305897 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0300398 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0295306 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0294978 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0291853 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0291788 |
| DSG2 | desmoglein 2 | 0.0288391 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0287025 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0286116 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.02852 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0279851 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0278072 |
| CDCP1 | CUB domain containing protein 1 | 0.0276686 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0271343 |
| NUP98 | nucleoporin 98kDa | 0.0270406 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0265174 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0264334 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0264004 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0262604 |
| GSE1 | Gse1 coiled-coil protein | 0.0261836 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0259956 |
| CD164 | CD164 molecule, sialomucin | 0.0259678 |
| RCOR1 | REST corepressor 1 | 0.0256435 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0255686 |
| EGFR | epidermal growth factor receptor | 0.0255108 |
| ANXA2 | annexin A2 | 0.0254411 |
| SNX9 | sorting nexin 9 | 0.0252751 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.025047 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0248456 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0246507 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0245905 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0245662 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0245153 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0244615 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0242753 |
| CLEC16A | C-type lectin domain family 16, member A | 0.0240249 |
| BCL2L1 | BCL2-like 1 | 0.0238647 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0238263 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0235222 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0234894 |
| NCKAP1 | NCK-associated protein 1 | 0.0234501 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0234219 |
| NUP58 | nucleoporin 58 | 0.0234033 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.17184 |
| TMSB10 | thymosin beta 10 | -0.143456 |
| TBC1D22A | TBC1 domain family, member 22A | -0.120793 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.11192 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0988485 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0944597 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0826887 |
| RAD51B | RAD51 paralog B | -0.0819322 |
| NDRG1 | N-myc downstream regulated 1 | -0.0810842 |
| AHNAK | AHNAK nucleoprotein | -0.0693302 |
| SERINC5 | serine incorporator 5 | -0.0635165 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0607898 |
| INTS6 | integrator complex subunit 6 | -0.0598483 |
| PRELID2 | PRELI domain containing 2 | -0.0575482 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.056332 |
| CTBP2 | C-terminal binding protein 2 | -0.0562247 |
| MSI2 | musashi RNA-binding protein 2 | -0.0553347 |
| FHIT | fragile histidine triad | -0.0527512 |
| RPL35A | ribosomal protein L35a | -0.04953 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0483269 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0477398 |
| RPLP2 | ribosomal protein, large, P2 | -0.0474251 |
| CANX | calnexin | -0.0472119 |
| RPS27A | ribosomal protein S27a | -0.0457609 |
| RPS19 | ribosomal protein S19 | -0.0441206 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0433925 |
| SBF2 | SET binding factor 2 | -0.0431259 |
| HDLBP | high density lipoprotein binding protein | -0.0429687 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0428883 |
| ARF4 | ADP-ribosylation factor 4 | -0.041746 |
| CADPS | Ca++-dependent secretion activator | -0.0415478 |
| RPL34 | ribosomal protein L34 | -0.0414675 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0403622 |
| RPL23 | ribosomal protein L23 | -0.0377592 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0376955 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0370211 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0359539 |
| RPL7A | ribosomal protein L7a | -0.0357491 |
| RPS29 | ribosomal protein S29 | -0.0356229 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0352741 |
| HOXB3 | homeobox B3 | -0.0352556 |
| RPS24 | ribosomal protein S24 | -0.0351592 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0349802 |
| LRRC23 | leucine rich repeat containing 23 | -0.0345722 |
| SEC24D | SEC24 family member D | -0.0339268 |
| RPL37A | ribosomal protein L37a | -0.0326122 |
| ATM | ATM serine/threonine kinase | -0.0315124 |
| FN1 | fibronectin 1 | -0.0314576 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0313111 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0312582 |
| FTL | ferritin, light polypeptide | -0.0312487 |
| GOLGB1 | golgin B1 | -0.0306522 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0303987 |
| RPL12 | ribosomal protein L12 | -0.0303401 |
| WWOX | WW domain containing oxidoreductase | -0.0299273 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0298428 |
| DYM | dymeclin | -0.0295652 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0295642 |
| OGA | O-GlcNAcase | -0.0295565 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.029351 |
| RPL31 | ribosomal protein L31 | -0.0289335 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.0288185 |
| HMGA2 | high mobility group AT-hook 2 | -0.0285537 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0284982 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0281826 |
| RPL26 | ribosomal protein L26 | -0.0278328 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0276206 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0275185 |
| RPS8 | ribosomal protein S8 | -0.0274718 |
| MYOF | myoferlin | -0.0271618 |
| MEF2A | myocyte enhancer factor 2A | -0.0270258 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0267442 |
| COG6 | component of oligomeric golgi complex 6 | -0.0267221 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0265221 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0256222 |
| RPL32 | ribosomal protein L32 | -0.0255581 |
| RPL19 | ribosomal protein L19 | -0.025233 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0251838 |
| RPS21 | ribosomal protein S21 | -0.0249892 |
| FNDC3B | fibronectin type III domain containing 3B | -0.024948 |
| ZNF395 | zinc finger protein 395 | -0.0248404 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.024824 |
| RPL11 | ribosomal protein L11 | -0.0248132 |
| MTAP | methylthioadenosine phosphorylase | -0.0247321 |
| RPS17 | ribosomal protein S17 | -0.0247053 |
| RPS13 | ribosomal protein S13 | -0.0245156 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0244945 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0243473 |
| LMNA | lamin A/C | -0.0241513 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0239357 |
| SNX14 | sorting nexin 14 | -0.02329 |
| PDE8A | phosphodiesterase 8A | -0.0231576 |
| RBM26 | RNA binding motif protein 26 | -0.0230309 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0229651 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0229163 |
| ZNRF3 | zinc and ring finger 3 | -0.0228238 |
| CCNY | cyclin Y | -0.0227506 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0226828 |
| RPS14 | ribosomal protein S14 | -0.0226629 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0225997 |
