| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.241022 |
| PKM | pyruvate kinase, muscle | 0.151089 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.143834 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.119249 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0864924 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0850208 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0822732 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.077236 |
| ACTG1 | actin gamma 1 | 0.0768495 |
| LDHA | lactate dehydrogenase A | 0.0749843 |
| FLNA | filamin A, alpha | 0.066146 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0646571 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0600127 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0595508 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0588947 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0552715 |
| PGK1 | phosphoglycerate kinase 1 | 0.0540047 |
| RPS2 | ribosomal protein S2 | 0.0532186 |
| LOC112694756 | uncharaterized LOC112694756 | 0.049767 |
| ZNF292 | zinc finger protein 292 | 0.048545 |
| APP | amyloid beta (A4) precursor protein | 0.0449605 |
| NDRG1 | N-myc downstream regulated 1 | 0.0442572 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0422507 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0403892 |
| SMAD3 | SMAD family member 3 | 0.0400748 |
| HELZ | helicase with zinc finger | 0.0385627 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.037467 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0373599 |
| RPL13A | ribosomal protein L13a | 0.0370938 |
| CDCP1 | CUB domain containing protein 1 | 0.0364997 |
| RACK1 | receptor for activated C kinase 1 | 0.0358113 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0355572 |
| CALR | calreticulin | 0.0351962 |
| CCNL1 | cyclin L1 | 0.0350226 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0349624 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0339605 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.0339282 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0328787 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0325852 |
| YEATS2 | YEATS domain containing 2 | 0.0324308 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.032089 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0313255 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0311683 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0304222 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0303991 |
| SEPTIN7 | septin 7 | 0.0299159 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0298917 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0295808 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0282906 |
| DSG2 | desmoglein 2 | 0.0282197 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0281516 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0275593 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0264668 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0264373 |
| EGR1 | early growth response 1 | 0.0261415 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0260007 |
| MYADM | myeloid-associated differentiation marker | 0.0258848 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0251206 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0249068 |
| MYEOV | myeloma overexpressed | 0.0245156 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0242051 |
| RPL4 | ribosomal protein L4 | 0.0239744 |
| SCRN1 | secernin 1 | 0.0237335 |
| BPTF | bromodomain PHD finger transcription factor | 0.0237171 |
| RPS6 | ribosomal protein S6 | 0.0236673 |
| SNX9 | sorting nexin 9 | 0.0235616 |
| ARFGEF3 | ARFGEF family member 3 | 0.0231091 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0230334 |
| ZNF148 | zinc finger protein 148 | 0.02302 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0229082 |
| B2M | beta-2-microglobulin | 0.0228254 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0227285 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0226601 |
| PCBP2 | poly(rC) binding protein 2 | 0.0226491 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0225871 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.022413 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0223756 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0220924 |
| CCND1 | cyclin D1 | 0.0220786 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0220385 |
| PLEC | plectin | 0.0217443 |
| ANKRD36 | ankyrin repeat domain 36 | 0.021695 |
| ANXA2 | annexin A2 | 0.0216713 |
| KIF5B | kinesin family member 5B | 0.0216687 |
| SEPTIN2 | septin 2 | 0.0216547 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0215297 |
| PLS3 | plastin 3 | 0.0212394 |
| MKI67 | marker of proliferation Ki-67 | 0.0211986 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0210544 |
| GOLGA4 | golgin A4 | 0.0209249 |
| SPOPL | speckle-type POZ protein-like | 0.0208557 |
| WDR45B | WD repeat domain 45B | 0.0207495 |
| SEPTIN9 | septin 9 | 0.0207342 |
| RFX7 | regulatory factor X, 7 | 0.0205072 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0200822 |
| SFXN1 | sideroflexin 1 | 0.0197898 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0197432 |
| HELLS | helicase, lymphoid-specific | 0.0197046 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0195843 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0193672 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.146266 |
| MT2A | metallothionein 2A | -0.0864913 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0825114 |
| PAX8 | paired box 8 | -0.0760775 |
| AHNAK | AHNAK nucleoprotein | -0.0649294 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0649017 |
| ASPH | aspartate beta-hydroxylase | -0.0630079 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0519386 |
| ITGB8 | integrin, beta 8 | -0.0511778 |
| TMSB4X | thymosin beta 4, X-linked | -0.050706 |
| PTMA | prothymosin, alpha | -0.0455025 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0425173 |
| HMGA2 | high mobility group AT-hook 2 | -0.0417511 |
| WWC1 | WW and C2 domain containing 1 | -0.0415741 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0387882 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0386663 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0384503 |
| VCL | vinculin | -0.0384365 |
| LAMC2 | laminin, gamma 2 | -0.0376646 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0375438 |
| RPL32 | ribosomal protein L32 | -0.0365963 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0361219 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0360824 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0348233 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0337134 |
| FMNL2 | formin-like 2 | -0.0330964 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0330127 |
| SVIL | supervillin | -0.0324806 |
| FTL | ferritin, light polypeptide | -0.0323124 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.032122 |
| KRT7 | keratin 7, type II | -0.0315506 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0309099 |
| RPLP2 | ribosomal protein, large, P2 | -0.030589 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0303747 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0295855 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0295388 |
| RPL31 | ribosomal protein L31 | -0.0293489 |
| DIAPH3 | diaphanous-related formin 3 | -0.0291728 |
| INTS6 | integrator complex subunit 6 | -0.0290552 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0287372 |
| RPS19 | ribosomal protein S19 | -0.0286466 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0284184 |
| CCDC138 | coiled-coil domain containing 138 | -0.0278406 |
| SPATA13 | spermatogenesis associated 13 | -0.026981 |
| GPR39 | G protein-coupled receptor 39 | -0.0266511 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0264657 |
| S100A10 | S100 calcium binding protein A10 | -0.0263269 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0257123 |
| LAMA4 | laminin, alpha 4 | -0.0256965 |
| RPL23 | ribosomal protein L23 | -0.0254163 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0254001 |
| DPP4 | dipeptidyl-peptidase 4 | -0.025122 |
| RPS24 | ribosomal protein S24 | -0.0250334 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0248557 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.024732 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0246027 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0242888 |
| MTAP | methylthioadenosine phosphorylase | -0.02423 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0237054 |
| LMNA | lamin A/C | -0.0234165 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0234077 |
| ATG7 | autophagy related 7 | -0.023254 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0232463 |
| DOCK4 | dedicator of cytokinesis 4 | -0.023059 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0223254 |
| KAZN | kazrin, periplakin interacting protein | -0.0223001 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0222832 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0221886 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0221809 |
| VMP1 | vacuole membrane protein 1 | -0.021769 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.021706 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0213658 |
| KRT86 | keratin 86, type II | -0.0213083 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0212122 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.020814 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0207595 |
| RPS27A | ribosomal protein S27a | -0.0207556 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0207476 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0204491 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0204283 |
| MYO1E | myosin IE | -0.0204179 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0203226 |
| FHIT | fragile histidine triad | -0.0202447 |
| AEBP2 | AE binding protein 2 | -0.0202368 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0201675 |
| SP100 | SP100 nuclear antigen | -0.0200056 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.0196078 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.019314 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0192909 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0192579 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.018522 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.0185011 |
| RPS21 | ribosomal protein S21 | -0.0184277 |
| JMJD1C | jumonji domain containing 1C | -0.0183588 |
| CTBP2 | C-terminal binding protein 2 | -0.018355 |
| KLHL29 | kelch-like family member 29 | -0.0183049 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.018261 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.018161 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0181294 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0180143 |
