| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.211545 |
| COL6A3 | collagen, type VI, alpha 3 | 0.142083 |
| FN1 | fibronectin 1 | 0.112305 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.11073 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0949918 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0889353 |
| LOX | lysyl oxidase | 0.0711074 |
| LOXL2 | lysyl oxidase-like 2 | 0.0642116 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0640622 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0635875 |
| NAV2 | neuron navigator 2 | 0.0633985 |
| HMGA2 | high mobility group AT-hook 2 | 0.0627166 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.062514 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0574996 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0487223 |
| CDH13 | cadherin 13 | 0.0452453 |
| COL5A1 | collagen, type V, alpha 1 | 0.0447422 |
| VEGFA | vascular endothelial growth factor A | 0.0442979 |
| NAV1 | neuron navigator 1 | 0.0433563 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0422582 |
| EFNA5 | ephrin-A5 | 0.039656 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0382741 |
| EGFR | epidermal growth factor receptor | 0.0378157 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.034867 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0340393 |
| MYO1B | myosin IB | 0.0322969 |
| PGK1 | phosphoglycerate kinase 1 | 0.0318314 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0315559 |
| LDHA | lactate dehydrogenase A | 0.0308151 |
| NDRG1 | N-myc downstream regulated 1 | 0.0304524 |
| DNER | delta/notch-like EGF repeat containing | 0.0285709 |
| MYADM | myeloid-associated differentiation marker | 0.0283042 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0279494 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0273756 |
| ANGPTL4 | angiopoietin-like 4 | 0.0271727 |
| MCL1 | myeloid cell leukemia 1 | 0.0267919 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0266197 |
| GPC6 | glypican 6 | 0.0262309 |
| RPL35A | ribosomal protein L35a | 0.0251237 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0249946 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0241637 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0239421 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0238829 |
| STC1 | stanniocalcin 1 | 0.0238406 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0235449 |
| HLA-B | major histocompatibility complex, class I, B | 0.0234849 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0231862 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0227955 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0225397 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0222601 |
| ADM | adrenomedullin | 0.0219086 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0216731 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0215819 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.021574 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0215313 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0212222 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0209602 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0206162 |
| RPL9 | ribosomal protein L9 | 0.0202285 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0201771 |
| RNF220 | ring finger protein 220 | 0.0200818 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0197863 |
| HLA-A | major histocompatibility complex, class I, A | 0.019662 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0196124 |
| OSMR | oncostatin M receptor | 0.019457 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.019451 |
| AGO2 | argonaute RISC catalytic component 2 | 0.019442 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0193173 |
| GANAB | glucosidase, alpha; neutral AB | 0.0192468 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.018974 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0187394 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0186901 |
| ATXN1 | ataxin 1 | 0.0185845 |
| HM13 | histocompatibility (minor) 13 | 0.0185208 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0184467 |
| RPS25 | ribosomal protein S25 | 0.0183861 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0182112 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0180831 |
| RPS13 | ribosomal protein S13 | 0.0180523 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | 0.017917 |
| CABIN1 | calcineurin binding protein 1 | 0.0178328 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0172593 |
| IL1R1 | interleukin 1 receptor, type I | 0.0172232 |
| CDK13 | cyclin-dependent kinase 13 | 0.0171228 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0171068 |
| CD68 | CD68 molecule | 0.0169908 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0167643 |
| GLRX | glutaredoxin (thioltransferase) | 0.0164472 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0164385 |
| FAM13A | family with sequence similarity 13, member A | 0.0164262 |
| TBCA | tubulin folding cofactor A | 0.0163442 |
| IGF2 | insulin-like growth factor 2 | 0.0163219 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0162225 |
| INTS6 | integrator complex subunit 6 | 0.0160637 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.015911 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0157239 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0155596 |
| NCOR2 | nuclear receptor corepressor 2 | 0.015527 |
| TNS1 | tensin 1 | 0.0154482 |
| FLNA | filamin A, alpha | 0.0153059 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.264307 |
| VIM | vimentin | -0.20429 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.203716 |
| TMSB10 | thymosin beta 10 | -0.184124 |
| COL1A1 | collagen, type I, alpha 1 | -0.151067 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.132858 |
| FTL | ferritin, light polypeptide | -0.0786071 |
| COL1A2 | collagen, type I, alpha 2 | -0.0765479 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0753386 |
| INHBA | inhibin, beta A | -0.0729884 |
| VCAN | versican | -0.0710418 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0696907 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0662618 |
| PTMA | prothymosin, alpha | -0.0652025 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0635786 |
| MT1X | metallothionein 1X | -0.0625238 |
| TMSB4X | thymosin beta 4, X-linked | -0.0615061 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0611776 |
| CALD1 | caldesmon 1 | -0.0591475 |
| MAP1B | microtubule-associated protein 1B | -0.0580723 |
| TPM4 | tropomyosin 4 | -0.0572317 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.056373 |
| IER3 | immediate early response 3 | -0.0552468 |
| FBN1 | fibrillin 1 | -0.054138 |
| EXT1 | exostosin glycosyltransferase 1 | -0.054007 |
| ATP13A3 | ATPase type 13A3 | -0.0536252 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0520532 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0496248 |
| GOLGA4 | golgin A4 | -0.0478023 |
| AHNAK | AHNAK nucleoprotein | -0.0464013 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.045932 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0458274 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0448989 |
| CD44 | CD44 molecule (Indian blood group) | -0.0440258 |
| YBX1 | Y box binding protein 1 | -0.0424944 |
| CANX | calnexin | -0.0419861 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0399441 |
| ASPH | aspartate beta-hydroxylase | -0.0397559 |
| ZNF292 | zinc finger protein 292 | -0.0378065 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0375566 |
| RRBP1 | ribosome binding protein 1 | -0.0374328 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0373924 |
| SPAG9 | sperm associated antigen 9 | -0.037027 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0358237 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0357905 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0356602 |
| TFG | TRK-fused gene | -0.0354952 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0351738 |
| USP3 | ubiquitin specific peptidase 3 | -0.0350494 |
| HDLBP | high density lipoprotein binding protein | -0.0348665 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0345666 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0345055 |
| SQLE | squalene epoxidase | -0.0335214 |
| RPL19 | ribosomal protein L19 | -0.0332993 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0323953 |
| IL6ST | interleukin 6 signal transducer | -0.0323209 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0320105 |
| MAP4 | microtubule-associated protein 4 | -0.0317283 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0313586 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0309705 |
| LMNA | lamin A/C | -0.0306599 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0306552 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0304385 |
| CLINT1 | clathrin interactor 1 | -0.030307 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0302985 |
| QKI | QKI, KH domain containing, RNA binding | -0.0295897 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0288082 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0287338 |
| ANXA2 | annexin A2 | -0.0286863 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0285738 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0284435 |
| KLF6 | Kruppel-like factor 6 | -0.0283639 |
| RPL5 | ribosomal protein L5 | -0.0277312 |
| COL3A1 | collagen, type III, alpha 1 | -0.0276469 |
| RPL18 | ribosomal protein L18 | -0.0275894 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0273967 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0268768 |
| PDE10A | phosphodiesterase 10A | -0.026566 |
| CADM1 | cell adhesion molecule 1 | -0.0264689 |
| RLF | rearranged L-myc fusion | -0.0263404 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0263156 |
| PRELID2 | PRELI domain containing 2 | -0.026199 |
| MRTFA | myocardin related transcription factor A | -0.0260574 |
| POSTN | periostin, osteoblast specific factor | -0.0258855 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0257281 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0256648 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0255662 |
| RPL8 | ribosomal protein L8 | -0.0252043 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0251368 |
| VCL | vinculin | -0.0247313 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0247031 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0243927 |
| S100A6 | S100 calcium binding protein A6 | -0.0243455 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0242788 |
| RPL32 | ribosomal protein L32 | -0.0242759 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0242263 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0240237 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0240187 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0239015 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0238738 |
