| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.094204 |
| POTEF | POTE ankyrin domain family, member F | 0.0686184 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0565333 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0492685 |
| BCL2L1 | BCL2-like 1 | 0.0464133 |
| FAT1 | FAT atypical cadherin 1 | 0.0459313 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0441263 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.041599 |
| AGRN | agrin | 0.0375787 |
| CCNL1 | cyclin L1 | 0.037192 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0336353 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0301553 |
| ZFP36 | ZFP36 ring finger protein | 0.029675 |
| CLDN4 | claudin 4 | 0.0296723 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0293356 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0286986 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0277542 |
| PKM | pyruvate kinase, muscle | 0.0271138 |
| STK24 | serine/threonine kinase 24 | 0.027072 |
| GSE1 | Gse1 coiled-coil protein | 0.0266548 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0264204 |
| HMGA1 | high mobility group AT-hook 1 | 0.0257576 |
| TNS4 | tensin 4 | 0.0255738 |
| FLNA | filamin A, alpha | 0.0252154 |
| WWC1 | WW and C2 domain containing 1 | 0.0251861 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0251549 |
| MSN | moesin | 0.0246951 |
| KLF10 | Kruppel-like factor 10 | 0.0243564 |
| NTN4 | netrin 4 | 0.0241566 |
| LAMA5 | laminin, alpha 5 | 0.0239303 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0232878 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.022787 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0224653 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0215336 |
| FLNB | filamin B, beta | 0.0214745 |
| MYADM | myeloid-associated differentiation marker | 0.0213091 |
| RPL23 | ribosomal protein L23 | 0.0210952 |
| ZNF207 | zinc finger protein 207 | 0.0204732 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0200081 |
| LATS2 | large tumor suppressor kinase 2 | 0.0199758 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.0197886 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0197639 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0197561 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0189281 |
| FOXO1 | forkhead box O1 | 0.0188445 |
| TJP2 | tight junction protein 2 | 0.0186991 |
| ITGB4 | integrin, beta 4 | 0.0184208 |
| NCOR2 | nuclear receptor corepressor 2 | 0.01801 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0180011 |
| JUP | junction plakoglobin | 0.0178588 |
| SFTPA2 | surfactant protein A2 | 0.0176643 |
| RBM47 | RNA binding motif protein 47 | 0.0174472 |
| FNBP4 | formin binding protein 4 | 0.0173618 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0169907 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.016893 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0168147 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0164557 |
| CLIC5 | chloride intracellular channel 5 | 0.0164447 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0163998 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0161841 |
| LMO7 | LIM domain 7 | 0.0161432 |
| ANXA11 | annexin A11 | 0.016119 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0158241 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0158221 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.015818 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0156777 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0156615 |
| LRATD2 | LRAT domain containing 2 | 0.0155183 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0154347 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0153611 |
| PDZD8 | PDZ domain containing 8 | 0.015263 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0151554 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0151531 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0147273 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0146928 |
| EGR1 | early growth response 1 | 0.0146497 |
| BRD2 | bromodomain containing 2 | 0.0146363 |
| RPS26 | ribosomal protein S26 | 0.0145212 |
| B2M | beta-2-microglobulin | 0.0144847 |
| PPL | periplakin | 0.0143535 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0141415 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0141396 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0140621 |
| SMAD3 | SMAD family member 3 | 0.0139578 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0139112 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0139009 |
| DNM2 | dynamin 2 | 0.0137096 |
| ERBIN | erbb2 interacting protein | 0.0135843 |
| MUC13 | mucin 13, cell surface associated | 0.0135827 |
| GANAB | glucosidase, alpha; neutral AB | 0.0134788 |
| C1D | C1D nuclear receptor corepressor | 0.0134039 |
| EPHA2 | EPH receptor A2 | 0.013338 |
| PFN1 | profilin 1 | 0.0133346 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0133059 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0132827 |
| TBC1D5 | TBC1 domain family, member 5 | 0.013086 |
| YAP1 | Yes-associated protein 1 | 0.0128804 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.0128035 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0128016 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0127178 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH14 | myosin, heavy chain 14, non-muscle | -0.136812 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.136563 |
| PTMA | prothymosin, alpha | -0.129447 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.125729 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.108195 |
| AHNAK | AHNAK nucleoprotein | -0.106766 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0979099 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0932851 |
| FRY | furry homolog (Drosophila) | -0.0875368 |
| SLC45A4 | solute carrier family 45, member 4 | -0.082002 |
| KRT20 | keratin 20, type I | -0.0764441 |
| TMSB10 | thymosin beta 10 | -0.0748386 |
| FTL | ferritin, light polypeptide | -0.0742906 |
| LAMA4 | laminin, alpha 4 | -0.0738871 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0728639 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0723395 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0722967 |
| INTS6 | integrator complex subunit 6 | -0.0690262 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0643416 |
| SQSTM1 | sequestosome 1 | -0.0608132 |
| AGR2 | anterior gradient 2 | -0.0592259 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0554941 |
| MMP7 | matrix metallopeptidase 7 | -0.0545659 |
| CANX | calnexin | -0.0541366 |
| RPS24 | ribosomal protein S24 | -0.0540304 |
| PRELID2 | PRELI domain containing 2 | -0.0531768 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.052069 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.052045 |
| ACTN4 | actinin, alpha 4 | -0.0511502 |
| RTN3 | reticulon 3 | -0.0507729 |
| ASPH | aspartate beta-hydroxylase | -0.0503083 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0502482 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0498479 |
| LYZ | lysozyme | -0.0470872 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.046876 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0463098 |
| POF1B | premature ovarian failure, 1B | -0.0458669 |
| HDLBP | high density lipoprotein binding protein | -0.0457152 |
| GOLGB1 | golgin B1 | -0.0452091 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0449143 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0434401 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0431867 |
| ANXA2 | annexin A2 | -0.042781 |
| NDRG1 | N-myc downstream regulated 1 | -0.0414808 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0413861 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0412202 |
| DIAPH2 | diaphanous-related formin 2 | -0.0396255 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0392407 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0392226 |
| TES | testin LIM domain protein | -0.0386706 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0379907 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.037808 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0370797 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0367789 |
| RPS3 | ribosomal protein S3 | -0.0366336 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0365477 |
| HM13 | histocompatibility (minor) 13 | -0.0363025 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0357723 |
| SDC4 | syndecan 4 | -0.0352071 |
| ATXN1 | ataxin 1 | -0.0348442 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0344572 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.033613 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0329926 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0325544 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0325425 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0323988 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0322636 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0322022 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0320361 |
| RPS8 | ribosomal protein S8 | -0.0316293 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0315366 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0312005 |
| TUFT1 | tuftelin 1 | -0.0305852 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0305473 |
| FOXO3 | forkhead box O3 | -0.0303108 |
| RPL34 | ribosomal protein L34 | -0.0301355 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0300403 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0295123 |
| EZR | ezrin | -0.029491 |
| S100A10 | S100 calcium binding protein A10 | -0.029422 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0291315 |
| RRBP1 | ribosome binding protein 1 | -0.0287281 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0286596 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0286528 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0285077 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0283945 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0283027 |
| GOLGA4 | golgin A4 | -0.02814 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0281299 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.028106 |
| RPS27A | ribosomal protein S27a | -0.0280428 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0274272 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0273053 |
| SNX14 | sorting nexin 14 | -0.0272802 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0272218 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0267413 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0267288 |
| EPCAM | epithelial cell adhesion molecule | -0.026664 |
| CD2AP | CD2-associated protein | -0.0261168 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0260805 |
