| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGM2 | transglutaminase 2 | 0.100636 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0673921 |
| MTSS1 | metastasis suppressor 1 | 0.0616448 |
| LAMA5 | laminin, alpha 5 | 0.0570739 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0568756 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0555557 |
| TNS4 | tensin 4 | 0.0520771 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0512924 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0505715 |
| HMGA2 | high mobility group AT-hook 2 | 0.0477936 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0461555 |
| PCDH1 | protocadherin 1 | 0.0439159 |
| FKBP5 | FK506 binding protein 5 | 0.0435115 |
| MSN | moesin | 0.0407205 |
| BCL2L1 | BCL2-like 1 | 0.0384017 |
| PODXL | podocalyxin-like | 0.0380812 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0376779 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0376464 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0360699 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0354922 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0331176 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0323587 |
| FOSL1 | FOS-like antigen 1 | 0.0318668 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0316279 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0310766 |
| ITGB4 | integrin, beta 4 | 0.0307213 |
| EGR1 | early growth response 1 | 0.0307144 |
| CALB1 | calbindin 1, 28kDa | 0.0293098 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.029239 |
| MCL1 | myeloid cell leukemia 1 | 0.0273519 |
| IGF2 | insulin-like growth factor 2 | 0.0270815 |
| PLS3 | plastin 3 | 0.0268718 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0267872 |
| NDRG1 | N-myc downstream regulated 1 | 0.0267746 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0266507 |
| PLEC | plectin | 0.0263049 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0262855 |
| LDHA | lactate dehydrogenase A | 0.0254533 |
| POTEF | POTE ankyrin domain family, member F | 0.0253009 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0250368 |
| CAV2 | caveolin 2 | 0.0249045 |
| MYADM | myeloid-associated differentiation marker | 0.024694 |
| LRRC8A | leucine rich repeat containing 8 family, member A | 0.0238175 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0237188 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0231087 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0218541 |
| EPHA2 | EPH receptor A2 | 0.0216548 |
| RAD51B | RAD51 paralog B | 0.021588 |
| RIN2 | Ras and Rab interactor 2 | 0.0204315 |
| JAG1 | jagged 1 | 0.0199291 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0197799 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.0190632 |
| FLNA | filamin A, alpha | 0.0189954 |
| CRACDL | CRACD like | 0.0186791 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0182332 |
| RASAL2 | RAS protein activator like 2 | 0.018146 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0179656 |
| ITGB8 | integrin, beta 8 | 0.0179088 |
| CAPRIN2 | caprin family member 2 | 0.0177476 |
| SEPTIN9 | septin 9 | 0.0177334 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.017354 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0171003 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0170661 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0170569 |
| PLAT | plasminogen activator, tissue | 0.0170278 |
| CD9 | CD9 molecule | 0.0167737 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0164236 |
| CCNL1 | cyclin L1 | 0.0164152 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0160761 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0159155 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0158455 |
| YAP1 | Yes-associated protein 1 | 0.0154985 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0153981 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0153746 |
| ABHD2 | abhydrolase domain containing 2 | 0.0152878 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0149597 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0149087 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0147977 |
| CLMB | calcimembrin | 0.0147703 |
| FAM120A | family with sequence similarity 120A | 0.014588 |
| STING1 | stimulator of interferon response cGAMP interactor 1 | 0.0144742 |
| ZNF395 | zinc finger protein 395 | 0.0143389 |
| IFI44L | interferon-induced protein 44-like | 0.0142831 |
| ABLIM2 | actin binding LIM protein family, member 2 | 0.0142458 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0142348 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0141946 |
| CDKL5 | cyclin-dependent kinase-like 5 | 0.0141195 |
| CLIC4 | chloride intracellular channel 4 | 0.0140014 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0139381 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.01392 |
| PER1 | period circadian clock 1 | 0.013919 |
| EFNA5 | ephrin-A5 | 0.0138985 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0138756 |
| CD68 | CD68 molecule | 0.0138401 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.01383 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0137326 |
| CDK19 | cyclin-dependent kinase 19 | 0.0135971 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0135733 |
| ATXN2L | ataxin 2-like | 0.0134338 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.0131799 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.233151 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.180773 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.160942 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.135993 |
| TMSB10 | thymosin beta 10 | -0.114565 |
| PTMA | prothymosin, alpha | -0.107853 |
| TMSB4X | thymosin beta 4, X-linked | -0.10235 |
| SULF1 | sulfatase 1 | -0.101187 |
| CLU | clusterin | -0.0962987 |
| AHNAK | AHNAK nucleoprotein | -0.0901901 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0855666 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0760436 |
| S100A10 | S100 calcium binding protein A10 | -0.0754747 |
| EXT1 | exostosin glycosyltransferase 1 | -0.07538 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0748965 |
| LMNA | lamin A/C | -0.0731816 |
| RBM39 | RNA binding motif protein 39 | -0.0717674 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0715858 |
| ITGA6 | integrin, alpha 6 | -0.0676102 |
| MECOM | MDS1 and EVI1 complex locus | -0.0659588 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0630658 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0628868 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0624608 |
| RPS21 | ribosomal protein S21 | -0.0609496 |
| CANX | calnexin | -0.0606425 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0602715 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0580038 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0573712 |
| FLNB | filamin B, beta | -0.0569046 |
| RPS8 | ribosomal protein S8 | -0.0550303 |
| PALLD | palladin, cytoskeletal associated protein | -0.0546048 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0523054 |
| B2M | beta-2-microglobulin | -0.0521227 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0512043 |
| GOLGA4 | golgin A4 | -0.051107 |
| NRG1 | neuregulin 1 | -0.0508168 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0508008 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0504571 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0496987 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0489701 |
| GNAS | GNAS complex locus | -0.048762 |
| HDLBP | high density lipoprotein binding protein | -0.04788 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0463466 |
| ASPH | aspartate beta-hydroxylase | -0.0456173 |
| RPS24 | ribosomal protein S24 | -0.0449489 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0445724 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0429213 |
| H1-0 | H1.0 linker histone | -0.0423396 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0422048 |
| MORF4L2 | mortality factor 4 like 2 | -0.041889 |
| RIGI | RNA sensor RIG-I | -0.0417293 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0417094 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0400889 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0398064 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0392411 |
| ENO1 | enolase 1, (alpha) | -0.0390673 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0386935 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0385077 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0374773 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0374291 |
| EMP1 | epithelial membrane protein 1 | -0.0367044 |
| RPL12 | ribosomal protein L12 | -0.0365329 |
| CALU | calumenin | -0.0363596 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.035954 |
| SQLE | squalene epoxidase | -0.0358962 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.035623 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.035568 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0354839 |
| NEK7 | NIMA-related kinase 7 | -0.0353035 |
| CAVIN1 | caveolae associated protein 1 | -0.0350235 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0349418 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0349255 |
| FOXO1 | forkhead box O1 | -0.0348892 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0343397 |
| PRELID2 | PRELI domain containing 2 | -0.0342412 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0340439 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.033711 |
| TKT | transketolase | -0.0336987 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0335203 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0332949 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0328688 |
| HLA-B | major histocompatibility complex, class I, B | -0.0327264 |
| LMO7 | LIM domain 7 | -0.0326716 |
| RPS3 | ribosomal protein S3 | -0.0322806 |
| KIAA1217 | KIAA1217 | -0.0321732 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0320026 |
| PGK1 | phosphoglycerate kinase 1 | -0.031718 |
| OGA | O-GlcNAcase | -0.0316762 |
| RPL34 | ribosomal protein L34 | -0.0314924 |
| EXOC6B | exocyst complex component 6B | -0.0311003 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.03105 |
| GLG1 | golgi glycoprotein 1 | -0.0307408 |
| ARF1 | ADP-ribosylation factor 1 | -0.0306203 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0305247 |
| HM13 | histocompatibility (minor) 13 | -0.0304665 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0303976 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0302565 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0300025 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.02995 |
| SPAG9 | sperm associated antigen 9 | -0.0297948 |
