| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.309995 |
| FN1 | fibronectin 1 | 0.261524 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.155075 |
| CD44 | CD44 molecule (Indian blood group) | 0.110783 |
| PODXL | podocalyxin-like | 0.0925402 |
| PGK1 | phosphoglycerate kinase 1 | 0.0910992 |
| LDHA | lactate dehydrogenase A | 0.0886087 |
| FLNB | filamin B, beta | 0.0830593 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.08214 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0750385 |
| FLNA | filamin A, alpha | 0.0734052 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0682795 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0677002 |
| ERBIN | erbb2 interacting protein | 0.0597273 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0573593 |
| PKM | pyruvate kinase, muscle | 0.0566043 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0561587 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0538771 |
| ZNF841 | zinc finger protein 841 | 0.052867 |
| OSMR | oncostatin M receptor | 0.0512636 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0492596 |
| POTEF | POTE ankyrin domain family, member F | 0.0482292 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0472358 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0469647 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0468454 |
| COL5A1 | collagen, type V, alpha 1 | 0.0467239 |
| NAV2 | neuron navigator 2 | 0.0459156 |
| ENO1 | enolase 1, (alpha) | 0.0456497 |
| NAV1 | neuron navigator 1 | 0.0434457 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0429057 |
| DST | dystonin | 0.0388262 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0381102 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0370163 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0368864 |
| EGFR | epidermal growth factor receptor | 0.0367456 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0363843 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0360378 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0356711 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0350451 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0346705 |
| ACTN1 | actinin, alpha 1 | 0.0343385 |
| ASPH | aspartate beta-hydroxylase | 0.0339931 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0338572 |
| ACTG1 | actin gamma 1 | 0.0333692 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0332384 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.033006 |
| MSN | moesin | 0.0329756 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0323319 |
| BCL2L1 | BCL2-like 1 | 0.0320484 |
| CCNL1 | cyclin L1 | 0.030578 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.030572 |
| SMAD3 | SMAD family member 3 | 0.029832 |
| L1CAM | L1 cell adhesion molecule | 0.0297642 |
| LOXL2 | lysyl oxidase-like 2 | 0.0289511 |
| DTNA | dystrobrevin, alpha | 0.0286346 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0285129 |
| ANXA5 | annexin A5 | 0.0281935 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0277601 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0272921 |
| LOX | lysyl oxidase | 0.0270909 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0265414 |
| RAD51B | RAD51 paralog B | 0.0262121 |
| ANXA2 | annexin A2 | 0.0260821 |
| FAM120A | family with sequence similarity 120A | 0.0253218 |
| MCL1 | myeloid cell leukemia 1 | 0.0252818 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.025097 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0250603 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0249739 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.024971 |
| GANAB | glucosidase, alpha; neutral AB | 0.0249579 |
| EFNA5 | ephrin-A5 | 0.0246381 |
| PTK2 | protein tyrosine kinase 2 | 0.0245582 |
| CCND1 | cyclin D1 | 0.0240581 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0238656 |
| FAT1 | FAT atypical cadherin 1 | 0.0237059 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0233519 |
| RNF213 | ring finger protein 213 | 0.0231516 |
| MT2A | metallothionein 2A | 0.0227926 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0227051 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0226488 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0225603 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0223142 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0218674 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0218328 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0217885 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0216401 |
| TGM2 | transglutaminase 2 | 0.0211712 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0209815 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0209764 |
| TUBA1C | tubulin, alpha 1c | 0.0208996 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0205184 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0204118 |
| HMGA1 | high mobility group AT-hook 1 | 0.0202107 |
| ACER3 | alkaline ceramidase 3 | 0.0199151 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0196468 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0196217 |
| IL6ST | interleukin 6 signal transducer | 0.0195928 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0194468 |
| YEATS2 | YEATS domain containing 2 | 0.0194299 |
| SMYD3 | SET and MYND domain containing 3 | 0.0194217 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.290391 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.140013 |
| HLA-B | major histocompatibility complex, class I, B | -0.126999 |
| PTMA | prothymosin, alpha | -0.0956949 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0804083 |
| TMSB10 | thymosin beta 10 | -0.0800573 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0756021 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0634765 |
| TMSB4X | thymosin beta 4, X-linked | -0.0503653 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0499694 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0486597 |
| GOLGA4 | golgin A4 | -0.0459944 |
| B2M | beta-2-microglobulin | -0.0452618 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0419556 |
| DEK | DEK proto-oncogene | -0.0405149 |
| S100A10 | S100 calcium binding protein A10 | -0.0402041 |
| RPL12 | ribosomal protein L12 | -0.0378546 |
| VIM | vimentin | -0.0371745 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0361956 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0359315 |
| RPS8 | ribosomal protein S8 | -0.0358739 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0347669 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0342205 |
| RBM39 | RNA binding motif protein 39 | -0.0336885 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0331144 |
| RPL35A | ribosomal protein L35a | -0.0328404 |
| IER3 | immediate early response 3 | -0.0321613 |
| ARF4 | ADP-ribosylation factor 4 | -0.0321265 |
| RLF | rearranged L-myc fusion | -0.0320794 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0317741 |
| GNAS | GNAS complex locus | -0.0312558 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0309229 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0309199 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0302063 |
| SQSTM1 | sequestosome 1 | -0.0301584 |
| MORF4L2 | mortality factor 4 like 2 | -0.0291441 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.028869 |
| CANX | calnexin | -0.0286226 |
| PLIN2 | perilipin 2 | -0.0285338 |
| TGFB2 | transforming growth factor, beta 2 | -0.0284185 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0283078 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0283004 |
| HMGB1 | high mobility group box 1 | -0.0275362 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0271897 |
| JUN | jun proto-oncogene | -0.026895 |
| PLCB4 | phospholipase C, beta 4 | -0.0266674 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0265473 |
| RPL26 | ribosomal protein L26 | -0.0258861 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0257554 |
| RPS24 | ribosomal protein S24 | -0.0257331 |
| NOP58 | NOP58 ribonucleoprotein | -0.0253937 |
| TKT | transketolase | -0.0250884 |
| USP3 | ubiquitin specific peptidase 3 | -0.0248832 |
| RPL19 | ribosomal protein L19 | -0.0246817 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0245081 |
| RPLP2 | ribosomal protein, large, P2 | -0.0244093 |
| MT1X | metallothionein 1X | -0.024114 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0234327 |
| TPD52 | tumor protein D52 | -0.0234188 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0231302 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0229977 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0229951 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0228912 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0228899 |
| RPL34 | ribosomal protein L34 | -0.0228811 |
| SERF2 | small EDRK-rich factor 2 | -0.0227165 |
| RPL31 | ribosomal protein L31 | -0.0222296 |
| TXNRD1 | thioredoxin reductase 1 | -0.022082 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0218814 |
| SUCO | SUN domain containing ossification factor | -0.0218659 |
| RPS3 | ribosomal protein S3 | -0.0217918 |
| SRP54 | signal recognition particle 54kDa | -0.0214856 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0212565 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0212301 |
| LMNA | lamin A/C | -0.0211927 |
| TMEM263 | transmembrane protein 263 | -0.0210924 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0210242 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0210218 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0209797 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0207316 |
| HMGB2 | high mobility group box 2 | -0.0205769 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0203785 |
| S100A6 | S100 calcium binding protein A6 | -0.0203194 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0203049 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0202933 |
| QKI | QKI, KH domain containing, RNA binding | -0.0201624 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0201345 |
| CTSD | cathepsin D | -0.019954 |
| RHEB | Ras homolog enriched in brain | -0.0197811 |
| RPS19 | ribosomal protein S19 | -0.0196912 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0196545 |
| RPS6 | ribosomal protein S6 | -0.0196398 |
| RPL32 | ribosomal protein L32 | -0.0192991 |
| KRT18 | keratin 18, type I | -0.0192215 |
| NOL7 | nucleolar protein 7, 27kDa | -0.0191316 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.018953 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0188599 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0188391 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0187504 |
| MYL12B | myosin, light chain 12B, regulatory | -0.018741 |
