| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.185558 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.155344 |
| LDHA | lactate dehydrogenase A | 0.134479 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.120074 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.110228 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.106263 |
| MUC13 | mucin 13, cell surface associated | 0.100972 |
| PKM | pyruvate kinase, muscle | 0.0986135 |
| PGK1 | phosphoglycerate kinase 1 | 0.0955443 |
| MYO1E | myosin IE | 0.0947734 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0875479 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0847468 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0823129 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0767008 |
| MUC17 | mucin 17, cell surface associated | 0.0699969 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0698411 |
| ANXA2 | annexin A2 | 0.0689733 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0683766 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0673543 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0672448 |
| ABHD2 | abhydrolase domain containing 2 | 0.0645382 |
| TPM4 | tropomyosin 4 | 0.0578874 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0526644 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0525386 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0491009 |
| TNS4 | tensin 4 | 0.0484956 |
| CADPS | Ca++-dependent secretion activator | 0.0457042 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0438205 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0425407 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0418367 |
| PIGR | polymeric immunoglobulin receptor | 0.0385623 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0382825 |
| DSG2 | desmoglein 2 | 0.0380042 |
| DSPP | dentin sialophosphoprotein | 0.0376858 |
| TMEM45B | transmembrane protein 45B | 0.0375887 |
| PRSS3 | protease, serine, 3 | 0.037069 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0365857 |
| ENO1 | enolase 1, (alpha) | 0.035921 |
| RPS2 | ribosomal protein S2 | 0.0353533 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0349348 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | 0.0348684 |
| RIGI | RNA sensor RIG-I | 0.0344156 |
| NEBL | nebulette | 0.0340211 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0337692 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0330067 |
| KLF6 | Kruppel-like factor 6 | 0.0323346 |
| RPLP0 | ribosomal protein, large, P0 | 0.0322372 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0316217 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0314854 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0314495 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0314037 |
| MXD1 | MAX dimerization protein 1 | 0.0311866 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0308128 |
| EREG | epiregulin | 0.0303584 |
| ITGB4 | integrin, beta 4 | 0.0303486 |
| PDZD8 | PDZ domain containing 8 | 0.030287 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0301391 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.029937 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0297979 |
| FHL2 | four and a half LIM domains 2 | 0.0297506 |
| KIF5B | kinesin family member 5B | 0.0297125 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0294302 |
| H1-0 | H1.0 linker histone | 0.0294232 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0290786 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0288102 |
| RPL4 | ribosomal protein L4 | 0.0283166 |
| ACTG1 | actin gamma 1 | 0.0277476 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0276994 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0272542 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0268943 |
| AFF1 | AF4/FMR2 family, member 1 | 0.026873 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0263036 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0260731 |
| PCDH9 | protocadherin 9 | 0.0258006 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.025635 |
| ADD3 | adducin 3 (gamma) | 0.0255875 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0250551 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0247298 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0247251 |
| MT1E | metallothionein 1E | 0.0242358 |
| CTSB | cathepsin B | 0.0242063 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0237395 |
| PKP2 | plakophilin 2 | 0.0237183 |
| NDRG1 | N-myc downstream regulated 1 | 0.0233025 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.0231727 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0231522 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0231119 |
| EHF | ets homologous factor | 0.0228022 |
| AGR2 | anterior gradient 2 | 0.0227856 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0225865 |
| TMEM123 | transmembrane protein 123 | 0.022136 |
| CDCP1 | CUB domain containing protein 1 | 0.0221153 |
| FOXO1 | forkhead box O1 | 0.0218065 |
| TSPAN8 | tetraspanin 8 | 0.0217308 |
| TBC1D5 | TBC1 domain family, member 5 | 0.021714 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0216728 |
| GDF15 | growth differentiation factor 15 | 0.0216421 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0214902 |
| RPL6 | ribosomal protein L6 | 0.0212257 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0209218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.189588 |
| NPSR1 | neuropeptide S receptor 1 | -0.116337 |
| PTMA | prothymosin, alpha | -0.0986833 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0899489 |
| ITGA6 | integrin, alpha 6 | -0.0662053 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.065187 |
| COG5 | component of oligomeric golgi complex 5 | -0.0640222 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0620048 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0619434 |
| RPS19 | ribosomal protein S19 | -0.0611297 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.058661 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0546788 |
| RPLP2 | ribosomal protein, large, P2 | -0.0545847 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.052425 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0497023 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0490908 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0488178 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0470616 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0458224 |
| RRBP1 | ribosome binding protein 1 | -0.0455999 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0442239 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0438416 |
| RNF145 | ring finger protein 145 | -0.0427789 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0427378 |
| RBM39 | RNA binding motif protein 39 | -0.042539 |
| RPL5 | ribosomal protein L5 | -0.0417519 |
| SBF2 | SET binding factor 2 | -0.0415301 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0413321 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0401524 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0400555 |
| RPL12 | ribosomal protein L12 | -0.0400366 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0386469 |
| AHNAK | AHNAK nucleoprotein | -0.0384986 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0383414 |
| RPS21 | ribosomal protein S21 | -0.0380472 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0375552 |
| RPL23 | ribosomal protein L23 | -0.0366862 |
| RPL36 | ribosomal protein L36 | -0.0363785 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0363629 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.035962 |
| MED13L | mediator complex subunit 13-like | -0.0358871 |
| TFG | TRK-fused gene | -0.0356098 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0355193 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0354662 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0352605 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0352591 |
| RPL9 | ribosomal protein L9 | -0.033851 |
| SLC35F3 | solute carrier family 35, member F3 | -0.033591 |
| LMNA | lamin A/C | -0.033529 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0335153 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0333353 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0332291 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0331311 |
| CD47 | CD47 molecule | -0.0330832 |
| ZNF292 | zinc finger protein 292 | -0.0330502 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0327614 |
| EZR | ezrin | -0.0320184 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0318005 |
| RPL31 | ribosomal protein L31 | -0.0316699 |
| PTEN | phosphatase and tensin homolog | -0.0316667 |
| NOP58 | NOP58 ribonucleoprotein | -0.0315465 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0314299 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0313608 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0313434 |
| LMO7 | LIM domain 7 | -0.0311816 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0310706 |
| ASPH | aspartate beta-hydroxylase | -0.0310211 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0307469 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0306783 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0306579 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.03055 |
| CDK13 | cyclin-dependent kinase 13 | -0.0302646 |
| SETD5 | SET domain containing 5 | -0.0302611 |
| RPL32 | ribosomal protein L32 | -0.0301414 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0299239 |
| USP34 | ubiquitin specific peptidase 34 | -0.0299035 |
| USP53 | ubiquitin specific peptidase 53 | -0.0298914 |
| EFNB2 | ephrin-B2 | -0.0297202 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0296103 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.02941 |
| GOLGA4 | golgin A4 | -0.0293476 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.029281 |
| VMP1 | vacuole membrane protein 1 | -0.0292187 |
| GOLGB1 | golgin B1 | -0.0287278 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0286571 |
| RPL37A | ribosomal protein L37a | -0.0283155 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0283127 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0281381 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0279122 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0278782 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0276439 |
| CTBP2 | C-terminal binding protein 2 | -0.0275449 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0275323 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0272616 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0272538 |
| CCNY | cyclin Y | -0.0272434 |
| BBX | bobby sox homolog (Drosophila) | -0.0271948 |
| S100P | S100 calcium binding protein P | -0.0271923 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0271208 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.026805 |
