| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPLP1 | ribosomal protein, large, P1 | 0.165171 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.113541 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.103499 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0875436 |
| PKM | pyruvate kinase, muscle | 0.0868849 |
| RPLP0 | ribosomal protein, large, P0 | 0.0859016 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0832239 |
| FLNB | filamin B, beta | 0.0713212 |
| RPL4 | ribosomal protein L4 | 0.0705254 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0673369 |
| TMSB10 | thymosin beta 10 | 0.0655171 |
| PGK1 | phosphoglycerate kinase 1 | 0.0615515 |
| LDHA | lactate dehydrogenase A | 0.0610959 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0600645 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0578451 |
| ANXA2 | annexin A2 | 0.0575575 |
| PTMA | prothymosin, alpha | 0.0434009 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.043177 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0426994 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0424015 |
| ITGB4 | integrin, beta 4 | 0.041024 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0399284 |
| RACK1 | receptor for activated C kinase 1 | 0.0392454 |
| ACTG1 | actin gamma 1 | 0.0379694 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0375169 |
| KLF6 | Kruppel-like factor 6 | 0.0369382 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0347555 |
| RPL35A | ribosomal protein L35a | 0.0345907 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0343402 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0335825 |
| MYO1E | myosin IE | 0.0323893 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0320101 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0310753 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0286434 |
| PALLD | palladin, cytoskeletal associated protein | 0.0286251 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0272492 |
| APP | amyloid beta (A4) precursor protein | 0.0269783 |
| KRT8 | keratin 8, type II | 0.0266294 |
| KRT18 | keratin 18, type I | 0.0255091 |
| CUX1 | cut-like homeobox 1 | 0.0252837 |
| AHNAK | AHNAK nucleoprotein | 0.0251003 |
| PYGB | phosphorylase, glycogen; brain | 0.0250508 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0248568 |
| RPL34 | ribosomal protein L34 | 0.0243449 |
| H1-0 | H1.0 linker histone | 0.0241184 |
| TUBB | tubulin, beta class I | 0.0240773 |
| EPHA2 | EPH receptor A2 | 0.0238306 |
| RPL27A | ribosomal protein L27a | 0.0237495 |
| RPL30 | ribosomal protein L30 | 0.023451 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0232049 |
| TPM4 | tropomyosin 4 | 0.0231569 |
| ARF1 | ADP-ribosylation factor 1 | 0.0227071 |
| RPL39 | ribosomal protein L39 | 0.0224526 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0224075 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0220695 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0216056 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0216053 |
| EGR1 | early growth response 1 | 0.0215225 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0213399 |
| PRSS3 | protease, serine, 3 | 0.0207289 |
| CALR | calreticulin | 0.0207231 |
| RPS16 | ribosomal protein S16 | 0.0206207 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0204241 |
| RPL13A | ribosomal protein L13a | 0.020423 |
| ATP10B | ATPase, class V, type 10B | 0.0203902 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0201986 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0196688 |
| DNM2 | dynamin 2 | 0.0196192 |
| KRT19 | keratin 19, type I | 0.0194088 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0194003 |
| PCBP1 | poly(rC) binding protein 1 | 0.0193407 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0191732 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0189839 |
| HMGA1 | high mobility group AT-hook 1 | 0.0189578 |
| RPS4X | ribosomal protein S4, X-linked | 0.0185056 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0184099 |
| RREB1 | ras responsive element binding protein 1 | 0.018369 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0182025 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0180928 |
| NRN1 | neuritin 1 | 0.0177316 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0176756 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0175553 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.0174389 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0173407 |
| RPS20 | ribosomal protein S20 | 0.0172685 |
| CD164 | CD164 molecule, sialomucin | 0.0170344 |
| OXSR1 | oxidative stress responsive 1 | 0.0169491 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0168255 |
| TC2N | tandem C2 domains, nuclear | 0.0167195 |
| ENO1 | enolase 1, (alpha) | 0.0167008 |
| DSG2 | desmoglein 2 | 0.0163547 |
| RPL8 | ribosomal protein L8 | 0.0162288 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0161907 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0160076 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0157775 |
| BCL2L1 | BCL2-like 1 | 0.0156149 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0154097 |
| GNAS | GNAS complex locus | 0.0153826 |
| TMEM123 | transmembrane protein 123 | 0.0153067 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | 0.0151326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.104997 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.103154 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0801472 |
| RPS2 | ribosomal protein S2 | -0.07886 |
| RPL9 | ribosomal protein L9 | -0.0651388 |
| GOLGA4 | golgin A4 | -0.0608245 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0559462 |
| ATXN1 | ataxin 1 | -0.0552901 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0544532 |
| LMO7 | LIM domain 7 | -0.0544378 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0524998 |
| TXNRD1 | thioredoxin reductase 1 | -0.0522324 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0515262 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0502479 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0495815 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0491724 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0484858 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0482718 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0475794 |
| RPS23 | ribosomal protein S23 | -0.0454326 |
| RPL3 | ribosomal protein L3 | -0.0443752 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0442926 |
| ASPH | aspartate beta-hydroxylase | -0.0432665 |
| GOLGB1 | golgin B1 | -0.042971 |
| PCBP2 | poly(rC) binding protein 2 | -0.0425556 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0423064 |
| RIGI | RNA sensor RIG-I | -0.0410095 |
| RPS13 | ribosomal protein S13 | -0.0407216 |
| MYO6 | myosin VI | -0.0396721 |
| HLA-B | major histocompatibility complex, class I, B | -0.0395046 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0392319 |
| RAD51B | RAD51 paralog B | -0.0390024 |
| TRIM2 | tripartite motif containing 2 | -0.0383842 |
| AREG | amphiregulin | -0.0381438 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.037962 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0378322 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0377728 |
| SQSTM1 | sequestosome 1 | -0.0371634 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0368728 |
| PRELID2 | PRELI domain containing 2 | -0.0367365 |
| SETD5 | SET domain containing 5 | -0.0364911 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0364171 |
| INTS6 | integrator complex subunit 6 | -0.0363534 |
| RNF145 | ring finger protein 145 | -0.0363242 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0356199 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0350212 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0349525 |
| RPL21 | ribosomal protein L21 | -0.0348271 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0347882 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0347127 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0340743 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.033995 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0337062 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0334172 |
| RBM39 | RNA binding motif protein 39 | -0.0326723 |
| VMP1 | vacuole membrane protein 1 | -0.0317924 |
| ITGA6 | integrin, alpha 6 | -0.0317607 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.031605 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.031096 |
| CCPG1 | cell cycle progression 1 | -0.0308841 |
| RPL36 | ribosomal protein L36 | -0.0308437 |
| NKTR | natural killer cell triggering receptor | -0.0307865 |
| RPS19 | ribosomal protein S19 | -0.0306486 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0306279 |
| COG5 | component of oligomeric golgi complex 5 | -0.0303694 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0303242 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.029677 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0295174 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0293233 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0292754 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0290129 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0289612 |
| COG6 | component of oligomeric golgi complex 6 | -0.0287458 |
| TMF1 | TATA element modulatory factor 1 | -0.028727 |
| ZNF638 | zinc finger protein 638 | -0.0286394 |
| EREG | epiregulin | -0.028516 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0278149 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0277213 |
| DSPP | dentin sialophosphoprotein | -0.0275576 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0274901 |
| MX1 | MX dynamin-like GTPase 1 | -0.026749 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0267012 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0266611 |
| USP53 | ubiquitin specific peptidase 53 | -0.0265486 |
| NEBL | nebulette | -0.0265302 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0264177 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0264156 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0262435 |
| PGM3 | phosphoglucomutase 3 | -0.0262385 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0259654 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0258664 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0258642 |
| PTEN | phosphatase and tensin homolog | -0.0256771 |
| UTRN | utrophin | -0.0253806 |
| MX2 | MX dynamin-like GTPase 2 | -0.0253045 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.025243 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0250053 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.0249335 |
| RNF213 | ring finger protein 213 | -0.024498 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0244908 |
