| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.229569 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.104087 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0890892 |
| CAPRIN2 | caprin family member 2 | 0.0679812 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0662292 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0655603 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0654138 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0637605 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0606859 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0589306 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0582222 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0581248 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0560355 |
| LDHA | lactate dehydrogenase A | 0.0548554 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0513114 |
| HMGA1 | high mobility group AT-hook 1 | 0.0511993 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0443122 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0436901 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0432717 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.040948 |
| RNF213 | ring finger protein 213 | 0.040453 |
| CD44 | CD44 molecule (Indian blood group) | 0.0402373 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0400552 |
| TP63 | tumor protein p63 | 0.0397715 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0392702 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0384271 |
| ENO1 | enolase 1, (alpha) | 0.0374564 |
| HLA-B | major histocompatibility complex, class I, B | 0.0358867 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0350097 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0341531 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0334155 |
| ANGPTL4 | angiopoietin-like 4 | 0.0332532 |
| SLK | STE20-like kinase | 0.0325291 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0321069 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0306735 |
| PGK1 | phosphoglycerate kinase 1 | 0.0304459 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0301263 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0295133 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0287091 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0284165 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0283857 |
| RPL35A | ribosomal protein L35a | 0.0283149 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0277747 |
| CTSC | cathepsin C | 0.0266967 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0264433 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0263318 |
| CADM2 | cell adhesion molecule 2 | 0.0262923 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0262826 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0262309 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0250028 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0245977 |
| TPM4 | tropomyosin 4 | 0.0243085 |
| RPL39 | ribosomal protein L39 | 0.0242152 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0241287 |
| PFKL | phosphofructokinase, liver | 0.0238701 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0235338 |
| B2M | beta-2-microglobulin | 0.0234324 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.023384 |
| NHSL1 | NHS-like 1 | 0.0233711 |
| PODXL | podocalyxin-like | 0.0231946 |
| MEF2A | myocyte enhancer factor 2A | 0.0231624 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0231143 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0230132 |
| RPL4 | ribosomal protein L4 | 0.0229224 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0228986 |
| BARX2 | BARX homeobox 2 | 0.0228114 |
| ZFR | zinc finger RNA binding protein | 0.0226996 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0221136 |
| ARFGEF3 | ARFGEF family member 3 | 0.0219532 |
| RUNX1 | runt-related transcription factor 1 | 0.0218475 |
| RIGI | RNA sensor RIG-I | 0.0217946 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0212627 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0212153 |
| EREG | epiregulin | 0.0211284 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0210671 |
| H1-0 | H1.0 linker histone | 0.0209674 |
| RPL27 | ribosomal protein L27 | 0.0209535 |
| HLA-E | major histocompatibility complex, class I, E | 0.0209227 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0207662 |
| CCNL1 | cyclin L1 | 0.0206356 |
| PRNP | prion protein | 0.0205157 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0204815 |
| IRS1 | insulin receptor substrate 1 | 0.0203499 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0202187 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0201529 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0195805 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0194987 |
| YBX3 | Y box binding protein 3 | 0.0193129 |
| APP | amyloid beta (A4) precursor protein | 0.0192075 |
| TXNIP | thioredoxin interacting protein | 0.0191732 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0191508 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0186557 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0186494 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0185571 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0185309 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0185084 |
| GANAB | glucosidase, alpha; neutral AB | 0.0183988 |
| NDRG1 | N-myc downstream regulated 1 | 0.0182211 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0181924 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0180008 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.173456 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.10859 |
| PTMA | prothymosin, alpha | -0.103135 |
| TMSB10 | thymosin beta 10 | -0.094011 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0835348 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0755039 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0578658 |
| VIM | vimentin | -0.055641 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0484426 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0406602 |
| CMIP | c-Maf inducing protein | -0.0398474 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0392601 |
| FUS | FUS RNA binding protein | -0.0381568 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0374525 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0373651 |
| EHBP1 | EH domain binding protein 1 | -0.0367781 |
| MT1E | metallothionein 1E | -0.0361437 |
| RCOR1 | REST corepressor 1 | -0.0352941 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0342109 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0335304 |
| RPS23 | ribosomal protein S23 | -0.0321883 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.031574 |
| CENPF | centromere protein F, 350/400kDa | -0.0311157 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0307194 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0306507 |
| TMSB4X | thymosin beta 4, X-linked | -0.030302 |
| AHNAK | AHNAK nucleoprotein | -0.0296144 |
| TXNRD1 | thioredoxin reductase 1 | -0.0293718 |
| FMNL2 | formin-like 2 | -0.0292418 |
| DIAPH3 | diaphanous-related formin 3 | -0.0290102 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0285096 |
| RPL23 | ribosomal protein L23 | -0.0276484 |
| RPS8 | ribosomal protein S8 | -0.0276334 |
| SBF2 | SET binding factor 2 | -0.0274724 |
| RPLP2 | ribosomal protein, large, P2 | -0.0274291 |
| RPL5 | ribosomal protein L5 | -0.0266797 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0266341 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0260077 |
| ECT2 | epithelial cell transforming 2 | -0.0258144 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0255227 |
| OLA1 | Obg-like ATPase 1 | -0.0244094 |
| PCBP2 | poly(rC) binding protein 2 | -0.024236 |
| USP34 | ubiquitin specific peptidase 34 | -0.0241754 |
| INTS6 | integrator complex subunit 6 | -0.0237415 |
| RPS21 | ribosomal protein S21 | -0.0235999 |
| MEMO1 | mediator of cell motility 1 | -0.0235675 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0235567 |
| NEK10 | NIMA-related kinase 10 | -0.0234385 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0232688 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0232571 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0232147 |
| SMAD3 | SMAD family member 3 | -0.0227785 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0225128 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0223826 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.022303 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0221136 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0217674 |
| JMJD1C | jumonji domain containing 1C | -0.021609 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0215144 |
| EZR | ezrin | -0.0214979 |
| FTL | ferritin, light polypeptide | -0.0214568 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0213865 |
| HDLBP | high density lipoprotein binding protein | -0.0213248 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0212877 |
| POTEF | POTE ankyrin domain family, member F | -0.0212653 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0211322 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.021011 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0208473 |
| CDK6 | cyclin-dependent kinase 6 | -0.0203594 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0203403 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0202572 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.0202059 |
| PHIP | pleckstrin homology domain interacting protein | -0.020152 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0201379 |
| RPL31 | ribosomal protein L31 | -0.0201373 |
| RASAL2 | RAS protein activator like 2 | -0.019771 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0197566 |
| SPAG9 | sperm associated antigen 9 | -0.0195171 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0195157 |
| RPS19 | ribosomal protein S19 | -0.0193823 |
| SRGN | serglycin | -0.0191677 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0190372 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0190066 |
| HOMER1 | homer scaffolding protein 1 | -0.0187572 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0187553 |
| S100A10 | S100 calcium binding protein A10 | -0.0185925 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.018559 |
| BRD4 | bromodomain containing 4 | -0.0185545 |
| UBAP2 | ubiquitin associated protein 2 | -0.0184262 |
| RAI1 | retinoic acid induced 1 | -0.0184116 |
| EXOC4 | exocyst complex component 4 | -0.0183429 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0182581 |
| FLNB | filamin B, beta | -0.0182246 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0181203 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0180452 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0179545 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0179089 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0178944 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0178238 |
| DST | dystonin | -0.0178075 |
