| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.190388 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0966082 |
| TGM2 | transglutaminase 2 | 0.0925914 |
| HMGA2 | high mobility group AT-hook 2 | 0.0845458 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0771496 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0731471 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0650116 |
| LOX | lysyl oxidase | 0.0634058 |
| ANKRD28 | ankyrin repeat domain 28 | 0.057733 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.057518 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0539726 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.052399 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.05192 |
| EFNA5 | ephrin-A5 | 0.0479191 |
| FKBP5 | FK506 binding protein 5 | 0.0472602 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0423902 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.041861 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0371523 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.035456 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0350937 |
| FN1 | fibronectin 1 | 0.0337275 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0331077 |
| TLR2 | toll-like receptor 2 | 0.032315 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.030922 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0306567 |
| NAV2 | neuron navigator 2 | 0.0304157 |
| NRCAM | neuronal cell adhesion molecule | 0.0293373 |
| NRP1 | neuropilin 1 | 0.0292142 |
| SMAD3 | SMAD family member 3 | 0.028997 |
| RUNX2 | runt-related transcription factor 2 | 0.0289514 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0271677 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.02662 |
| HAS2 | hyaluronan synthase 2 | 0.0263782 |
| CD44 | CD44 molecule (Indian blood group) | 0.0249045 |
| MCL1 | myeloid cell leukemia 1 | 0.0246905 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0246856 |
| ANGPTL4 | angiopoietin-like 4 | 0.0243235 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0243174 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0226439 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0224238 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0221808 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0213529 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.021352 |
| PCNX1 | pecanex 1 | 0.0212307 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.0211391 |
| SIK3 | SIK family kinase 3 | 0.0209377 |
| OSMR | oncostatin M receptor | 0.0206981 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0204356 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0202872 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0202252 |
| DNER | delta/notch-like EGF repeat containing | 0.020189 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0200896 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0200598 |
| GPC6 | glypican 6 | 0.0197802 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0194919 |
| IL6ST | interleukin 6 signal transducer | 0.0190152 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.018788 |
| NRG1 | neuregulin 1 | 0.0187693 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.018718 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0183855 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0182771 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0181577 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.018116 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0180256 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0177373 |
| CUL4B | cullin 4B | 0.0176773 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.017647 |
| IL1R1 | interleukin 1 receptor, type I | 0.0175708 |
| NEBL | nebulette | 0.0172452 |
| RNF144A | ring finger protein 144A | 0.0170513 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0169785 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0167818 |
| FLNB | filamin B, beta | 0.0163285 |
| C1RL | complement component 1, r subcomponent-like | 0.0159642 |
| TOX2 | TOX high mobility group box family member 2 | 0.0158438 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0157928 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0155383 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0151738 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0150113 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0145916 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0144288 |
| TOP1 | topoisomerase (DNA) I | 0.0143364 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0140345 |
| MYO1E | myosin IE | 0.0139887 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0139876 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.0139525 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | 0.0136727 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0136423 |
| RNF24 | ring finger protein 24 | 0.0135344 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0133018 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0131852 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0131581 |
| ZNF638 | zinc finger protein 638 | 0.0130812 |
| MMP2 | matrix metallopeptidase 2 | 0.0128031 |
| STRA6 | stimulated by retinoic acid 6 | 0.0126983 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0123297 |
| ATP13A3 | ATPase type 13A3 | 0.0123015 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0122219 |
| MEIS1 | Meis homeobox 1 | 0.0121966 |
| FBXO32 | F-box protein 32 | 0.0121581 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.195443 |
| TMSB10 | thymosin beta 10 | -0.173678 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.137626 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0945219 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0914885 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0862392 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0857727 |
| STC1 | stanniocalcin 1 | -0.0839163 |
| PTMA | prothymosin, alpha | -0.0834981 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.072046 |
| FTL | ferritin, light polypeptide | -0.0672778 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0658357 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0642519 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0612668 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0561499 |
| CDH13 | cadherin 13 | -0.0553198 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0543553 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0527401 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0520995 |
| ENO1 | enolase 1, (alpha) | -0.0506955 |
| TMSB4X | thymosin beta 4, X-linked | -0.0491468 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0472504 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0470228 |
| DST | dystonin | -0.0460918 |
| GOLGA4 | golgin A4 | -0.0459003 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0454148 |
| IER3 | immediate early response 3 | -0.0453004 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0446891 |
| S100A6 | S100 calcium binding protein A6 | -0.042846 |
| MECOM | MDS1 and EVI1 complex locus | -0.0418968 |
| SYT1 | synaptotagmin I | -0.0418047 |
| RPLP1 | ribosomal protein, large, P1 | -0.0416285 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0414759 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0412226 |
| RPS8 | ribosomal protein S8 | -0.0411004 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0404918 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0402515 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0399018 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0397438 |
| GLCCI1 | glucocorticoid induced 1 | -0.0396437 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.039635 |
| AHNAK | AHNAK nucleoprotein | -0.0396332 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0395829 |
| CANX | calnexin | -0.0395714 |
| RAI14 | retinoic acid induced 14 | -0.0394337 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0392598 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0380656 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.037033 |
| RPL34 | ribosomal protein L34 | -0.0360226 |
| MTSS1 | metastasis suppressor 1 | -0.0356223 |
| RPS19 | ribosomal protein S19 | -0.035513 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0351917 |
| USP34 | ubiquitin specific peptidase 34 | -0.0349666 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0349512 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0348522 |
| RPS24 | ribosomal protein S24 | -0.034769 |
| FAM107B | family with sequence similarity 107, member B | -0.034628 |
| MAP1B | microtubule-associated protein 1B | -0.0344218 |
| RPS6 | ribosomal protein S6 | -0.0342847 |
| RPL35A | ribosomal protein L35a | -0.0323653 |
| SQSTM1 | sequestosome 1 | -0.0323193 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.031983 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0316905 |
| MEF2A | myocyte enhancer factor 2A | -0.0316322 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0315249 |
| FBN1 | fibrillin 1 | -0.0314446 |
| RPL31 | ribosomal protein L31 | -0.0311512 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.030908 |
| HDLBP | high density lipoprotein binding protein | -0.0307196 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0303594 |
| VCL | vinculin | -0.0303089 |
| RPL32 | ribosomal protein L32 | -0.0301842 |
| RPS21 | ribosomal protein S21 | -0.029981 |
| S100A10 | S100 calcium binding protein A10 | -0.0285614 |
| ASPH | aspartate beta-hydroxylase | -0.0283649 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0280966 |
| RPS29 | ribosomal protein S29 | -0.028079 |
| RPL23 | ribosomal protein L23 | -0.0280477 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0278176 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0277954 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0276856 |
| RPLP2 | ribosomal protein, large, P2 | -0.02768 |
| B2M | beta-2-microglobulin | -0.0275983 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0274274 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0270801 |
| RPL37A | ribosomal protein L37a | -0.0267936 |
| RPL12 | ribosomal protein L12 | -0.0267436 |
| CUX1 | cut-like homeobox 1 | -0.026544 |
| CDK14 | cyclin-dependent kinase 14 | -0.0264246 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0261053 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0260636 |
| GNAS | GNAS complex locus | -0.0260531 |
| ZNF804A | zinc finger protein 804A | -0.0256404 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0253942 |
| RPL19 | ribosomal protein L19 | -0.0253212 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0252248 |
| RPS25 | ribosomal protein S25 | -0.025198 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0248489 |
| RPS13 | ribosomal protein S13 | -0.02477 |
| RPS12 | ribosomal protein S12 | -0.0244232 |
