| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.300594 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.223517 |
| GRAMD1B | GRAM domain containing 1B | 0.172988 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.152288 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.120084 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.105448 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0931203 |
| MCL1 | myeloid cell leukemia 1 | 0.0919204 |
| FGA | fibrinogen alpha chain | 0.0824361 |
| NNMT | nicotinamide N-methyltransferase | 0.0737066 |
| LDHA | lactate dehydrogenase A | 0.0674028 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0653289 |
| FGB | fibrinogen beta chain | 0.0647407 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0638762 |
| PKM | pyruvate kinase, muscle | 0.0577656 |
| CCNL1 | cyclin L1 | 0.0555809 |
| POTEF | POTE ankyrin domain family, member F | 0.0545655 |
| EGR1 | early growth response 1 | 0.0530274 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0510067 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0500999 |
| PDE10A | phosphodiesterase 10A | 0.0460594 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0442407 |
| FLNA | filamin A, alpha | 0.0414855 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0390891 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0381554 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0379272 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0375455 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0364484 |
| HLA-A | major histocompatibility complex, class I, A | 0.0362605 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0349325 |
| DOCK5 | dedicator of cytokinesis 5 | 0.034848 |
| ACTG1 | actin gamma 1 | 0.0347884 |
| WWOX | WW domain containing oxidoreductase | 0.0341571 |
| RAD51B | RAD51 paralog B | 0.0336745 |
| KYNU | kynureninase | 0.0328721 |
| B2M | beta-2-microglobulin | 0.0323826 |
| BRD2 | bromodomain containing 2 | 0.0321909 |
| FGG | fibrinogen gamma chain | 0.0320418 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0313858 |
| PLS3 | plastin 3 | 0.0307828 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0302817 |
| SFTPA2 | surfactant protein A2 | 0.0301931 |
| ANGPTL4 | angiopoietin-like 4 | 0.0300361 |
| OSMR | oncostatin M receptor | 0.0296814 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0295483 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0295231 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0294107 |
| EFNA5 | ephrin-A5 | 0.0291766 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0281332 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0280907 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0278674 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0276232 |
| SVIL | supervillin | 0.0275925 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0271515 |
| RPL13A | ribosomal protein L13a | 0.0269834 |
| NTN4 | netrin 4 | 0.0269233 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0268452 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0262909 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0260833 |
| RPS2 | ribosomal protein S2 | 0.0259158 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0256581 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0255361 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.025372 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0252002 |
| LAMA5 | laminin, alpha 5 | 0.0251494 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0251406 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0248215 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0246681 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0246474 |
| PGK1 | phosphoglycerate kinase 1 | 0.0243762 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0240145 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0235042 |
| ATF4 | activating transcription factor 4 | 0.02348 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0233616 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0233613 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0229817 |
| PER1 | period circadian clock 1 | 0.0227934 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0222564 |
| RNF213 | ring finger protein 213 | 0.0221619 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0221422 |
| SLC39A9 | solute carrier family 39, member 9 | 0.022109 |
| SIK3 | SIK family kinase 3 | 0.0217934 |
| TGM2 | transglutaminase 2 | 0.021766 |
| GANAB | glucosidase, alpha; neutral AB | 0.0216078 |
| NCOR2 | nuclear receptor corepressor 2 | 0.021521 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0211143 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0211072 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0209945 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0207556 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0207418 |
| MEF2D | myocyte enhancer factor 2D | 0.0207191 |
| FAT1 | FAT atypical cadherin 1 | 0.0206124 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0204773 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0204765 |
| LDHB | lactate dehydrogenase B | 0.020419 |
| FOSL2 | FOS-like antigen 2 | 0.0203384 |
| MYADM | myeloid-associated differentiation marker | 0.0202692 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0201889 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0201743 |
| ZNF638 | zinc finger protein 638 | 0.0199427 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.162214 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.143464 |
| VIM | vimentin | -0.12187 |
| PTMA | prothymosin, alpha | -0.120815 |
| IER3 | immediate early response 3 | -0.114632 |
| FTL | ferritin, light polypeptide | -0.0991896 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0854412 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.075687 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0754507 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0752687 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0703198 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.067904 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0663161 |
| RPL19 | ribosomal protein L19 | -0.0657674 |
| TXNRD1 | thioredoxin reductase 1 | -0.0652223 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.058315 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0574322 |
| S100A10 | S100 calcium binding protein A10 | -0.0569086 |
| RBM39 | RNA binding motif protein 39 | -0.0557722 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0552849 |
| AHNAK | AHNAK nucleoprotein | -0.0495873 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0483887 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0444301 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0433905 |
| FMNL2 | formin-like 2 | -0.0392118 |
| TPD52 | tumor protein D52 | -0.0381339 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0374355 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0368758 |
| RPS24 | ribosomal protein S24 | -0.0363734 |
| ASPH | aspartate beta-hydroxylase | -0.0360804 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0360093 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0359181 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0347225 |
| PTK2 | protein tyrosine kinase 2 | -0.034277 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0342023 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0339327 |
| AK1 | adenylate kinase 1 | -0.0338886 |
| USP3 | ubiquitin specific peptidase 3 | -0.033742 |
| MAP1B | microtubule-associated protein 1B | -0.0337083 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0336179 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0333075 |
| KLF6 | Kruppel-like factor 6 | -0.0321302 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0317421 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.03173 |
| RPL31 | ribosomal protein L31 | -0.0317172 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0316708 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0316587 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0313981 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0307348 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0304301 |
| TES | testin LIM domain protein | -0.0303337 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0302168 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0294609 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0294362 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0289898 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0289756 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0286826 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0284906 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0284846 |
| RPL34 | ribosomal protein L34 | -0.0278141 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0274626 |
| CFDP1 | craniofacial development protein 1 | -0.0272236 |
| RBM25 | RNA binding motif protein 25 | -0.0266788 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0265988 |
| NAV3 | neuron navigator 3 | -0.0265532 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0265048 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.026455 |
| RPS11 | ribosomal protein S11 | -0.0263366 |
| NRG1 | neuregulin 1 | -0.0256754 |
| SERF2 | small EDRK-rich factor 2 | -0.0255178 |
| DOCK4 | dedicator of cytokinesis 4 | -0.025501 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0251761 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.025079 |
| PARD3 | par-3 family cell polarity regulator | -0.0247646 |
| EZR | ezrin | -0.0245689 |
| CANX | calnexin | -0.0244501 |
| TMSB4X | thymosin beta 4, X-linked | -0.0242043 |
| YME1L1 | YME1-like 1 ATPase | -0.0241725 |
| TNPO1 | transportin 1 | -0.0241382 |
| NOP58 | NOP58 ribonucleoprotein | -0.0239844 |
| ABI1 | abl-interactor 1 | -0.0238609 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0237483 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0235993 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0233213 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0232829 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.023229 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0230601 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0229789 |
| GOLGA4 | golgin A4 | -0.0229668 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.022957 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0228401 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0227355 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0226143 |
| MAP4 | microtubule-associated protein 4 | -0.0225153 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0224687 |
| RPS21 | ribosomal protein S21 | -0.0220758 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0220685 |
| TLK1 | tousled-like kinase 1 | -0.0220107 |
| TMEM87A | transmembrane protein 87A | -0.0218699 |
| FRMD5 | FERM domain containing 5 | -0.0217362 |
