| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.176052 |
| GRAMD1B | GRAM domain containing 1B | 0.155358 |
| TXNRD1 | thioredoxin reductase 1 | 0.121883 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.113781 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.108051 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.106648 |
| YBX3 | Y box binding protein 3 | 0.0985418 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0802253 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0790129 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0780789 |
| CCNL1 | cyclin L1 | 0.0625515 |
| PGK1 | phosphoglycerate kinase 1 | 0.0591191 |
| PDE10A | phosphodiesterase 10A | 0.0502529 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0477464 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0464457 |
| LATS2 | large tumor suppressor kinase 2 | 0.0459776 |
| TMEM41B | transmembrane protein 41B | 0.0433012 |
| EGR1 | early growth response 1 | 0.0423394 |
| RTN4 | reticulon 4 | 0.0399427 |
| ACTG1 | actin gamma 1 | 0.0391384 |
| PKM | pyruvate kinase, muscle | 0.0389296 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0382261 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0381699 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0337149 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0333875 |
| MMP12 | matrix metallopeptidase 12 | 0.0326798 |
| ICAM1 | intercellular adhesion molecule 1 | 0.032287 |
| STC1 | stanniocalcin 1 | 0.0321787 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0302924 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.02968 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0293426 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0291554 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0291164 |
| ATP11A | ATPase, class VI, type 11A | 0.0284703 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0276328 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.027614 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0264139 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0263537 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0259379 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0258658 |
| NUP58 | nucleoporin 58 | 0.025324 |
| LDHA | lactate dehydrogenase A | 0.0243846 |
| ATP13A3 | ATPase type 13A3 | 0.0243305 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0241484 |
| ITGB5 | integrin, beta 5 | 0.0236329 |
| YAP1 | Yes-associated protein 1 | 0.0235681 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0230891 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0228895 |
| FAM13A | family with sequence similarity 13, member A | 0.0228239 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0226277 |
| RPS2 | ribosomal protein S2 | 0.0225707 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0224971 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0221241 |
| PYGL | phosphorylase, glycogen, liver | 0.0221217 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0218969 |
| ARRDC3 | arrestin domain containing 3 | 0.0212515 |
| CLTC | clathrin, heavy chain (Hc) | 0.0211106 |
| ANXA5 | annexin A5 | 0.0209993 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0209365 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0206661 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0206239 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0205257 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0203511 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0201703 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0196843 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0196087 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0195985 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0195222 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0195152 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0194075 |
| ADAR | adenosine deaminase, RNA-specific | 0.0192464 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.019204 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0190449 |
| FOSL2 | FOS-like antigen 2 | 0.0190338 |
| MSN | moesin | 0.0190152 |
| APP | amyloid beta (A4) precursor protein | 0.0190096 |
| LOXL2 | lysyl oxidase-like 2 | 0.0189296 |
| AGRN | agrin | 0.0188653 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0187233 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0186404 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.018566 |
| FLNA | filamin A, alpha | 0.0185196 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0181923 |
| RNF216 | ring finger protein 216 | 0.0181569 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0181428 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0180802 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0180518 |
| PLS3 | plastin 3 | 0.0177322 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0175711 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0175107 |
| XPO1 | exportin 1 | 0.0175078 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0173907 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.0171112 |
| MYO6 | myosin VI | 0.0170114 |
| NUP155 | nucleoporin 155kDa | 0.0168944 |
| SEC24A | SEC24 family member A | 0.0167813 |
| RNF145 | ring finger protein 145 | 0.0167777 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0166782 |
| PRKCE | protein kinase C, epsilon | 0.0166288 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0164694 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.211337 |
| PTMA | prothymosin, alpha | -0.148023 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.120421 |
| VIM | vimentin | -0.110167 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0782138 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0578916 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0560936 |
| RPS3 | ribosomal protein S3 | -0.0560541 |
| RPL26 | ribosomal protein L26 | -0.0539445 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0537399 |
| AEBP2 | AE binding protein 2 | -0.0513057 |
| RPS8 | ribosomal protein S8 | -0.0493119 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0490504 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0485176 |
| RPS21 | ribosomal protein S21 | -0.047629 |
| RPL5 | ribosomal protein L5 | -0.0459678 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0455599 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0454288 |
| RPS27A | ribosomal protein S27a | -0.0444024 |
| RPL31 | ribosomal protein L31 | -0.0439867 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.043486 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0425263 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0407922 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0392361 |
| RPL12 | ribosomal protein L12 | -0.0389973 |
| VCL | vinculin | -0.0389598 |
| INTS6 | integrator complex subunit 6 | -0.0388338 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.038567 |
| RPL23 | ribosomal protein L23 | -0.0384387 |
| UBC | ubiquitin C | -0.038387 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0383348 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.038169 |
| RBM39 | RNA binding motif protein 39 | -0.0380876 |
| PCBP2 | poly(rC) binding protein 2 | -0.0375983 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0360394 |
| EHBP1 | EH domain binding protein 1 | -0.0348446 |
| USP34 | ubiquitin specific peptidase 34 | -0.034696 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0346195 |
| RPL11 | ribosomal protein L11 | -0.0346164 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0345186 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.033406 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0327533 |
| RPL19 | ribosomal protein L19 | -0.0326435 |
| CDK12 | cyclin-dependent kinase 12 | -0.0324868 |
| RPL37A | ribosomal protein L37a | -0.0323971 |
| DEK | DEK proto-oncogene | -0.0323462 |
| RPS24 | ribosomal protein S24 | -0.0319891 |
| AHNAK | AHNAK nucleoprotein | -0.0319018 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0317209 |
| FBXO11 | F-box protein 11 | -0.031622 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0315349 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0314538 |
| ATXN1 | ataxin 1 | -0.0311102 |
| S100A10 | S100 calcium binding protein A10 | -0.0304175 |
| RPS12 | ribosomal protein S12 | -0.0303062 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0302805 |
| HOMER1 | homer scaffolding protein 1 | -0.0296749 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0294452 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0293235 |
| CUX1 | cut-like homeobox 1 | -0.0292888 |
| SERINC3 | serine incorporator 3 | -0.0292669 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0289579 |
| RPL32 | ribosomal protein L32 | -0.0280063 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0280042 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0270706 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0266806 |
| PRELID2 | PRELI domain containing 2 | -0.026329 |
| MED13 | mediator complex subunit 13 | -0.0261761 |
| LRRC23 | leucine rich repeat containing 23 | -0.0255331 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0253351 |
| YBX1 | Y box binding protein 1 | -0.025304 |
| PRRC2C | proline-rich coiled-coil 2C | -0.025134 |
| MT2A | metallothionein 2A | -0.0246454 |
| NABP1 | nucleic acid binding protein 1 | -0.0241726 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0241483 |
| RPS15 | ribosomal protein S15 | -0.0239024 |
| RSF1 | remodeling and spacing factor 1 | -0.0238861 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0238861 |
| TOP1 | topoisomerase (DNA) I | -0.0237345 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0235695 |
| HLA-B | major histocompatibility complex, class I, B | -0.0232419 |
| KHSRP | KH-type splicing regulatory protein | -0.0231315 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.023127 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0230757 |
| RPS17 | ribosomal protein S17 | -0.0230224 |
| IER3 | immediate early response 3 | -0.0228488 |
| RYR3 | ryanodine receptor 3 | -0.0227764 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0226876 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0226793 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.0224792 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0223043 |
| RPS5 | ribosomal protein S5 | -0.0219301 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0217562 |
| RPS19 | ribosomal protein S19 | -0.0215987 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0215979 |
| RPL7A | ribosomal protein L7a | -0.0214865 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0214764 |
| RBM25 | RNA binding motif protein 25 | -0.0214098 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0213723 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.021366 |
