| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.235962 |
| ACTG1 | actin gamma 1 | 0.16565 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.140007 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0792505 |
| POTEF | POTE ankyrin domain family, member F | 0.0777788 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.062822 |
| CCNL1 | cyclin L1 | 0.0613288 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0611899 |
| EFNA5 | ephrin-A5 | 0.0504738 |
| LDHA | lactate dehydrogenase A | 0.0477361 |
| RPL9 | ribosomal protein L9 | 0.044817 |
| PKM | pyruvate kinase, muscle | 0.0433269 |
| LAMB3 | laminin, beta 3 | 0.0427601 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0426489 |
| BCL2L1 | BCL2-like 1 | 0.0419669 |
| CTSB | cathepsin B | 0.04143 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0403218 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0389985 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0377795 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0375977 |
| HOMER2 | homer scaffolding protein 2 | 0.0372 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0357862 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0355153 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0351149 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0342994 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0341346 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0337259 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0333026 |
| TMEM165 | transmembrane protein 165 | 0.0329443 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0317687 |
| RPL35A | ribosomal protein L35a | 0.031671 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0314319 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0306982 |
| FBXO32 | F-box protein 32 | 0.0306406 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0305118 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.029702 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0295803 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0293416 |
| KRT19 | keratin 19, type I | 0.0291081 |
| KRT7 | keratin 7, type II | 0.0289717 |
| FLNB | filamin B, beta | 0.0288876 |
| FLNA | filamin A, alpha | 0.0288747 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0286611 |
| S100A6 | S100 calcium binding protein A6 | 0.0284518 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0276613 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0272541 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0271898 |
| RPS2 | ribosomal protein S2 | 0.0270909 |
| HLA-B | major histocompatibility complex, class I, B | 0.0270805 |
| DUSP6 | dual specificity phosphatase 6 | 0.0270539 |
| MCL1 | myeloid cell leukemia 1 | 0.0259261 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0254282 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.023995 |
| SFTPA2 | surfactant protein A2 | 0.0239817 |
| PLEC | plectin | 0.0236662 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0234213 |
| CDCP1 | CUB domain containing protein 1 | 0.0233966 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0233347 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0232945 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0231484 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0230066 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0227533 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0226715 |
| CLTC | clathrin, heavy chain (Hc) | 0.0225376 |
| JUP | junction plakoglobin | 0.022202 |
| TXNIP | thioredoxin interacting protein | 0.0220138 |
| HLA-A | major histocompatibility complex, class I, A | 0.0215363 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0213271 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0209823 |
| NEBL | nebulette | 0.0209308 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0208488 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0208099 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0207935 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0207326 |
| VGLL3 | vestigial-like family member 3 | 0.0206493 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0205877 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0203908 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0201337 |
| PSEN1 | presenilin 1 | 0.0200737 |
| CDK13 | cyclin-dependent kinase 13 | 0.0199573 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.019903 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0197899 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0197518 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0197402 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.0196983 |
| LRATD2 | LRAT domain containing 2 | 0.0195397 |
| YY1 | YY1 transcription factor | 0.0191425 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0189828 |
| CTSA | cathepsin A | 0.0188838 |
| OCLN | occludin | 0.0187573 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.018671 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0186405 |
| EXOC5 | exocyst complex component 5 | 0.0185279 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0184336 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.0183568 |
| LTA4H | leukotriene A4 hydrolase | 0.018219 |
| CCND3 | cyclin D3 | 0.0181688 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.0177468 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0177119 |
| RPL27 | ribosomal protein L27 | 0.0176597 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.205218 |
| FTL | ferritin, light polypeptide | -0.187592 |
| ASPH | aspartate beta-hydroxylase | -0.172671 |
| TMSB10 | thymosin beta 10 | -0.169452 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.16758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.101862 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.101522 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0944353 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0878568 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0811824 |
| TMSB4X | thymosin beta 4, X-linked | -0.0775257 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.075817 |
| SQSTM1 | sequestosome 1 | -0.0726496 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.071685 |
| NDRG1 | N-myc downstream regulated 1 | -0.0712629 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0686707 |
| MT2A | metallothionein 2A | -0.0682573 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0681752 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0648796 |
| AHNAK | AHNAK nucleoprotein | -0.063889 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0629618 |
| LMO7 | LIM domain 7 | -0.0625728 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0619741 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0615587 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0590966 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0590702 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0575529 |
| CD2AP | CD2-associated protein | -0.0569176 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0568613 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0558072 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0546781 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0539145 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0519385 |
| RPL32 | ribosomal protein L32 | -0.0513965 |
| LAMC2 | laminin, gamma 2 | -0.0510225 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0510021 |
| HMGB2 | high mobility group box 2 | -0.0500682 |
| NAV2 | neuron navigator 2 | -0.0494301 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0493484 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0484421 |
| TXNRD1 | thioredoxin reductase 1 | -0.0473056 |
| S100A10 | S100 calcium binding protein A10 | -0.0442893 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0437022 |
| ZNF292 | zinc finger protein 292 | -0.0433591 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0432425 |
| EZR | ezrin | -0.0429782 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0428624 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0427864 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0425983 |
| MYO6 | myosin VI | -0.0425744 |
| QKI | QKI, KH domain containing, RNA binding | -0.0410147 |
| RYBP | RING1 and YY1 binding protein | -0.0409083 |
| ANLN | anillin, actin binding protein | -0.0402909 |
| RPS24 | ribosomal protein S24 | -0.0402688 |
| HMGA1 | high mobility group AT-hook 1 | -0.0387647 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.038659 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0383668 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0380379 |
| RLF | rearranged L-myc fusion | -0.0373896 |
| FAM162A | family with sequence similarity 162, member A | -0.0367622 |
| EPCAM | epithelial cell adhesion molecule | -0.0361413 |
| TMEM263 | transmembrane protein 263 | -0.0359978 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0356481 |
| VIM | vimentin | -0.0353288 |
| CENPF | centromere protein F, 350/400kDa | -0.03532 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0347311 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0343562 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0343047 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0339733 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0338872 |
| FOSL1 | FOS-like antigen 1 | -0.0335917 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0334653 |
| RNF145 | ring finger protein 145 | -0.0334354 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0326673 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0321844 |
| RPL12 | ribosomal protein L12 | -0.0321633 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0315556 |
| ENO1 | enolase 1, (alpha) | -0.0314742 |
| TFG | TRK-fused gene | -0.0313171 |
| YBX1 | Y box binding protein 1 | -0.0312016 |
| TPX2 | TPX2, microtubule-associated | -0.0311663 |
| CDC73 | cell division cycle 73 | -0.0311373 |
| FHIT | fragile histidine triad | -0.0310297 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0309273 |
| MSI2 | musashi RNA-binding protein 2 | -0.0305031 |
| SPAG9 | sperm associated antigen 9 | -0.0304982 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0304466 |
| MORF4L2 | mortality factor 4 like 2 | -0.0296383 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0296004 |
| RPS5 | ribosomal protein S5 | -0.0293338 |
| RPS3 | ribosomal protein S3 | -0.0289926 |
| RUNX1 | runt-related transcription factor 1 | -0.0289672 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0289236 |
| PLAU | plasminogen activator, urokinase | -0.0285609 |
| TUBA1B | tubulin, alpha 1b | -0.0283991 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0281812 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0277489 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0276745 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.02755 |
| MKI67 | marker of proliferation Ki-67 | -0.02746 |
