| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.375544 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.262517 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.178631 |
| ENO1 | enolase 1, (alpha) | 0.121475 |
| EGFR | epidermal growth factor receptor | 0.106852 |
| IGF1R | insulin-like growth factor 1 receptor | 0.104526 |
| EHBP1 | EH domain binding protein 1 | 0.102048 |
| GPC6 | glypican 6 | 0.101612 |
| MT2A | metallothionein 2A | 0.0968701 |
| S100A6 | S100 calcium binding protein A6 | 0.0939445 |
| HMGA2 | high mobility group AT-hook 2 | 0.0882382 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0859312 |
| SVIL | supervillin | 0.0849117 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0843382 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0843314 |
| FMN1 | formin 1 | 0.0823517 |
| SMYD3 | SET and MYND domain containing 3 | 0.077711 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0776635 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0769297 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0761564 |
| KRT8 | keratin 8, type II | 0.0721173 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0709219 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0698052 |
| LDHA | lactate dehydrogenase A | 0.0689578 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0689251 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0675052 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0670289 |
| FTL | ferritin, light polypeptide | 0.0615696 |
| PTK2 | protein tyrosine kinase 2 | 0.0614363 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0611866 |
| ANXA2 | annexin A2 | 0.0556811 |
| AHNAK | AHNAK nucleoprotein | 0.0547687 |
| RACK1 | receptor for activated C kinase 1 | 0.0541718 |
| GOLGA4 | golgin A4 | 0.0506349 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0503631 |
| MED13L | mediator complex subunit 13-like | 0.0503104 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0502151 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0489261 |
| AOPEP | aminopeptidase O (putative) | 0.0478533 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0456176 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0449256 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0446835 |
| LOX | lysyl oxidase | 0.0443893 |
| RUNX1 | runt-related transcription factor 1 | 0.0441302 |
| ZNF292 | zinc finger protein 292 | 0.0433286 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.041477 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0409506 |
| OSMR | oncostatin M receptor | 0.0405395 |
| PKM | pyruvate kinase, muscle | 0.0403436 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0393045 |
| HLA-B | major histocompatibility complex, class I, B | 0.0390675 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0387243 |
| RPL26 | ribosomal protein L26 | 0.0375714 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0370709 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0363531 |
| ACTG1 | actin gamma 1 | 0.0357138 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0356092 |
| RAD51B | RAD51 paralog B | 0.0354262 |
| KIF5B | kinesin family member 5B | 0.0353101 |
| ERBIN | erbb2 interacting protein | 0.03496 |
| DST | dystonin | 0.0338519 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0313108 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0313061 |
| RPS16 | ribosomal protein S16 | 0.0312795 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.031278 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0285576 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0280034 |
| PCBP3 | poly(rC) binding protein 3 | 0.0279341 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0275709 |
| LAMB3 | laminin, beta 3 | 0.0274304 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0272044 |
| B2M | beta-2-microglobulin | 0.0269114 |
| NDRG1 | N-myc downstream regulated 1 | 0.0260762 |
| BPTF | bromodomain PHD finger transcription factor | 0.02494 |
| USP34 | ubiquitin specific peptidase 34 | 0.0238592 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0224096 |
| EFNA5 | ephrin-A5 | 0.0222176 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0219281 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0212341 |
| ZNF207 | zinc finger protein 207 | 0.0208039 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.020788 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0200076 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0174745 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0165364 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0165043 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0157672 |
| KRT18 | keratin 18, type I | 0.0155055 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0148494 |
| RPLP0 | ribosomal protein, large, P0 | 0.0142348 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0140503 |
| TMSB10 | thymosin beta 10 | 0.0137668 |
| FMNL2 | formin-like 2 | 0.0132809 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0129705 |
| SMAD3 | SMAD family member 3 | 0.0129362 |
| CUX1 | cut-like homeobox 1 | 0.0126501 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0124612 |
| PGK1 | phosphoglycerate kinase 1 | 0.0124057 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0108704 |
| CANX | calnexin | 0.0108391 |
| MYO1E | myosin IE | 0.01064 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.139076 |
| VIM | vimentin | -0.111841 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.111339 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.107133 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.10455 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.10398 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0972763 |
| RPS6 | ribosomal protein S6 | -0.096908 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0946308 |
| LAMA4 | laminin, alpha 4 | -0.094029 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0918895 |
| RORA | RAR-related orphan receptor A | -0.0827316 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0797171 |
| CDH13 | cadherin 13 | -0.0754021 |
| TXNRD1 | thioredoxin reductase 1 | -0.0750794 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0744581 |
| RSF1 | remodeling and spacing factor 1 | -0.0734402 |
| FAM13A | family with sequence similarity 13, member A | -0.0703387 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0676053 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0672751 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0665403 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0663075 |
| VMP1 | vacuole membrane protein 1 | -0.0662325 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0634515 |
| SPAG9 | sperm associated antigen 9 | -0.0633492 |
| STAG2 | stromal antigen 2 | -0.0626297 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0619689 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.059944 |
| RPL15 | ribosomal protein L15 | -0.0597949 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0594534 |
| RPS19 | ribosomal protein S19 | -0.0588407 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.056969 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.054882 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0539538 |
| PDE10A | phosphodiesterase 10A | -0.0539389 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0535632 |
| GOLGB1 | golgin B1 | -0.0497077 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0489373 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0489147 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0477449 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0461016 |
| NHSL1 | NHS-like 1 | -0.0450982 |
| RPL23 | ribosomal protein L23 | -0.0439116 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0433155 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0432742 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0420461 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0420248 |
| FNIP1 | folliculin interacting protein 1 | -0.0420005 |
| RPS11 | ribosomal protein S11 | -0.0419981 |
| PRELID2 | PRELI domain containing 2 | -0.0409486 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.039386 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.039227 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0392076 |
| RPL11 | ribosomal protein L11 | -0.0381312 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0376965 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0362305 |
| RPLP1 | ribosomal protein, large, P1 | -0.0360455 |
| ATXN1 | ataxin 1 | -0.035367 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0352043 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0346552 |
| RPS13 | ribosomal protein S13 | -0.0335101 |
| JMJD1C | jumonji domain containing 1C | -0.033466 |
| RPL12 | ribosomal protein L12 | -0.0333107 |
| SBF2 | SET binding factor 2 | -0.0320308 |
| RPL34 | ribosomal protein L34 | -0.0318095 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0314186 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0306291 |
| OGA | O-GlcNAcase | -0.0303776 |
| CMIP | c-Maf inducing protein | -0.0302601 |
| NAV2 | neuron navigator 2 | -0.0298417 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0295997 |
| POTEF | POTE ankyrin domain family, member F | -0.0295484 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0290761 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0280448 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0279867 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0277842 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0272456 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0263026 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0261297 |
| RBM39 | RNA binding motif protein 39 | -0.0259601 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.025951 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0259004 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0258372 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0258254 |
| CALU | calumenin | -0.0254094 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0253792 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0252025 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0240459 |
| SLTM | SAFB-like, transcription modulator | -0.0240398 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0240034 |
| RPL35A | ribosomal protein L35a | -0.023866 |
| GRAMD1B | GRAM domain containing 1B | -0.0237367 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0232868 |
| MED13 | mediator complex subunit 13 | -0.0232084 |
| ASPH | aspartate beta-hydroxylase | -0.0215558 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0213899 |
| PRKCA | protein kinase C, alpha | -0.0212309 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0207137 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0200841 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0200811 |
