| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.125542 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0846546 |
| SFTPA2 | surfactant protein A2 | 0.0823934 |
| PGK1 | phosphoglycerate kinase 1 | 0.0787509 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0769646 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.075869 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0667244 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0662769 |
| EGFR | epidermal growth factor receptor | 0.062038 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0583158 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0504775 |
| EGR1 | early growth response 1 | 0.0477006 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0474071 |
| ZNF780B | zinc finger protein 780B | 0.0472485 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.046977 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0464396 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0460601 |
| ACTG1 | actin gamma 1 | 0.0460254 |
| MT2A | metallothionein 2A | 0.0459984 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0458437 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0451458 |
| RPLP1 | ribosomal protein, large, P1 | 0.044627 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0439467 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0425845 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.039687 |
| CAVIN1 | caveolae associated protein 1 | 0.0396735 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0389017 |
| RPL35A | ribosomal protein L35a | 0.0386169 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.037907 |
| ANGPTL4 | angiopoietin-like 4 | 0.0375359 |
| RNF220 | ring finger protein 220 | 0.0366784 |
| OSMR | oncostatin M receptor | 0.0361012 |
| LDHA | lactate dehydrogenase A | 0.0353652 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0343478 |
| TRIM66 | tripartite motif containing 66 | 0.0343127 |
| FLNA | filamin A, alpha | 0.0340272 |
| RPS16 | ribosomal protein S16 | 0.0336016 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0329881 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0321394 |
| PKM | pyruvate kinase, muscle | 0.0321017 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0319733 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0319029 |
| HMGA2 | high mobility group AT-hook 2 | 0.0310163 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0308397 |
| GANAB | glucosidase, alpha; neutral AB | 0.0307894 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0306342 |
| ITGB5 | integrin, beta 5 | 0.0303835 |
| PLEC | plectin | 0.0303239 |
| MKI67 | marker of proliferation Ki-67 | 0.0302861 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0299309 |
| PHF14 | PHD finger protein 14 | 0.0295061 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0294058 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0291102 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0288104 |
| RPL38 | ribosomal protein L38 | 0.0287958 |
| RPS2 | ribosomal protein S2 | 0.0287399 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.028213 |
| RPL37 | ribosomal protein L37 | 0.0281323 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0279777 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0278142 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0273572 |
| VCL | vinculin | 0.0269769 |
| RIGI | RNA sensor RIG-I | 0.0268635 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0261058 |
| MCL1 | myeloid cell leukemia 1 | 0.0259292 |
| ATG10 | autophagy related 10 | 0.0258887 |
| NUP98 | nucleoporin 98kDa | 0.025837 |
| FHL2 | four and a half LIM domains 2 | 0.025589 |
| SMYD3 | SET and MYND domain containing 3 | 0.0251594 |
| BMERB1 | bMERB domain containing 1 | 0.0250587 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0248161 |
| AOPEP | aminopeptidase O (putative) | 0.0247005 |
| EXOC6B | exocyst complex component 6B | 0.024547 |
| ACTN4 | actinin, alpha 4 | 0.0238835 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0238406 |
| BCL2L1 | BCL2-like 1 | 0.0238087 |
| EID2 | EP300 interacting inhibitor of differentiation 2 | 0.02364 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0236011 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0231495 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0229448 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0228683 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0228673 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0227692 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0225166 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0223811 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0222577 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0221123 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0215643 |
| RPL9 | ribosomal protein L9 | 0.0215637 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.021376 |
| RAD51B | RAD51 paralog B | 0.021166 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0208997 |
| EXOC4 | exocyst complex component 4 | 0.0206563 |
| TBCA | tubulin folding cofactor A | 0.0201988 |
| MYO9A | myosin IXA | 0.0200149 |
| RPS29 | ribosomal protein S29 | 0.0199584 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0199514 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0198779 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0196418 |
| TRIM56 | tripartite motif containing 56 | 0.0195039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.331079 |
| PTMA | prothymosin, alpha | -0.226467 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.151595 |
| TMSB10 | thymosin beta 10 | -0.129924 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.124666 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.124095 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120301 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0880297 |
| YBX1 | Y box binding protein 1 | -0.0790653 |
| JMJD1C | jumonji domain containing 1C | -0.0720349 |
| FMNL2 | formin-like 2 | -0.0717107 |
| SNX14 | sorting nexin 14 | -0.0683576 |
| GOLGA4 | golgin A4 | -0.0681322 |
| SPAG9 | sperm associated antigen 9 | -0.0680218 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0673975 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0671817 |
| FTL | ferritin, light polypeptide | -0.0657771 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0643625 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0608471 |
| PCBP2 | poly(rC) binding protein 2 | -0.0556511 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0547368 |
| TMEM123 | transmembrane protein 123 | -0.0526137 |
| MORF4L2 | mortality factor 4 like 2 | -0.0514462 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0509122 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0507023 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0498298 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.049575 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0481763 |
| CD109 | CD109 molecule | -0.0466349 |
| OGA | O-GlcNAcase | -0.0456227 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.044983 |
| UBC | ubiquitin C | -0.0449232 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0437028 |
| CENPF | centromere protein F, 350/400kDa | -0.0433452 |
| MATR3 | matrin 3 | -0.0428657 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0424385 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0419861 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0416448 |
| MED13L | mediator complex subunit 13-like | -0.0411539 |
| RPS5 | ribosomal protein S5 | -0.0410675 |
| ZNF292 | zinc finger protein 292 | -0.0389816 |
| S100A10 | S100 calcium binding protein A10 | -0.0387399 |
| PERP | PERP, TP53 apoptosis effector | -0.0383332 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0380875 |
| CANX | calnexin | -0.0380565 |
| USP3 | ubiquitin specific peptidase 3 | -0.037799 |
| SUCO | SUN domain containing ossification factor | -0.0377938 |
| ZFP36 | ZFP36 ring finger protein | -0.0370797 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0369465 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0364753 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0362125 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0344539 |
| S100A6 | S100 calcium binding protein A6 | -0.034409 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0342811 |
| SETD5 | SET domain containing 5 | -0.0342606 |
| FBL | fibrillarin | -0.0342337 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.03384 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0337603 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0336745 |
| CBX3 | chromobox homolog 3 | -0.0336289 |
| ARF4 | ADP-ribosylation factor 4 | -0.033458 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0334515 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0327459 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.032707 |
| SNX3 | sorting nexin 3 | -0.03258 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0322782 |
| SRP54 | signal recognition particle 54kDa | -0.0316459 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0315526 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0315412 |
| SEC24A | SEC24 family member A | -0.0312524 |
| TFG | TRK-fused gene | -0.0311493 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0311467 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.030996 |
| NOP58 | NOP58 ribonucleoprotein | -0.0306452 |
| WASF2 | WAS protein family, member 2 | -0.0306055 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0302295 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0300188 |
| DSTN | destrin (actin depolymerizing factor) | -0.0298522 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0297826 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0296633 |
| ECT2 | epithelial cell transforming 2 | -0.029556 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0293007 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0292697 |
| PFN1 | profilin 1 | -0.0292161 |
| TPX2 | TPX2, microtubule-associated | -0.0291842 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0291395 |
| WDR45B | WD repeat domain 45B | -0.0282775 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0278013 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0277336 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0275084 |
| COG5 | component of oligomeric golgi complex 5 | -0.0274488 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0272591 |
| IPO7 | importin 7 | -0.0270203 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0269064 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0267663 |
| NUP58 | nucleoporin 58 | -0.0266955 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0266118 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.026283 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0262385 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0261734 |
