| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.108774 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0906386 |
| TGM2 | transglutaminase 2 | 0.0864815 |
| RPS6 | ribosomal protein S6 | 0.0649697 |
| MUC16 | mucin 16, cell surface associated | 0.0636921 |
| LDHA | lactate dehydrogenase A | 0.0622017 |
| EFNA5 | ephrin-A5 | 0.0600202 |
| HMGA1 | high mobility group AT-hook 1 | 0.0554124 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0509767 |
| ACTG1 | actin gamma 1 | 0.0503644 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0496242 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0481409 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0477216 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0450608 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0450073 |
| SMAD3 | SMAD family member 3 | 0.0449353 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0429609 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0417304 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0398454 |
| POTEF | POTE ankyrin domain family, member F | 0.0394542 |
| RPLP1 | ribosomal protein, large, P1 | 0.0388981 |
| RPS8 | ribosomal protein S8 | 0.0387502 |
| CCND3 | cyclin D3 | 0.0383937 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0365632 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0356859 |
| RPL35A | ribosomal protein L35a | 0.0354375 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0353367 |
| CCNL1 | cyclin L1 | 0.0331353 |
| C3 | complement component 3 | 0.0325016 |
| VEGFA | vascular endothelial growth factor A | 0.0322056 |
| RACK1 | receptor for activated C kinase 1 | 0.0321116 |
| PKM | pyruvate kinase, muscle | 0.0313736 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.031353 |
| RPL30 | ribosomal protein L30 | 0.0313079 |
| RPL39 | ribosomal protein L39 | 0.0310242 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0309936 |
| FLNA | filamin A, alpha | 0.030681 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0304365 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0303976 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.027602 |
| PLEC | plectin | 0.0271713 |
| RPL37A | ribosomal protein L37a | 0.0271644 |
| RPS2 | ribosomal protein S2 | 0.0268359 |
| RPS17 | ribosomal protein S17 | 0.025875 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0254075 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0251063 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0242817 |
| EFNB2 | ephrin-B2 | 0.0242308 |
| FMNL2 | formin-like 2 | 0.024018 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0237269 |
| H2AC6 | H2A clustered histone 6 | 0.0226118 |
| KRT19 | keratin 19, type I | 0.0225469 |
| ARRDC3 | arrestin domain containing 3 | 0.022355 |
| IFI44L | interferon-induced protein 44-like | 0.0222281 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0220088 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0220045 |
| RPL13A | ribosomal protein L13a | 0.0219205 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0218653 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0217594 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0216955 |
| MCL1 | myeloid cell leukemia 1 | 0.0216749 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0215212 |
| DSPP | dentin sialophosphoprotein | 0.0211275 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0207107 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.020705 |
| TXNIP | thioredoxin interacting protein | 0.0204632 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0200696 |
| BRD2 | bromodomain containing 2 | 0.0198754 |
| RPS20 | ribosomal protein S20 | 0.0194458 |
| RPL37 | ribosomal protein L37 | 0.0194311 |
| CSNK1D | casein kinase 1, delta | 0.0192809 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.019052 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0188729 |
| RPS12 | ribosomal protein S12 | 0.018796 |
| CD44 | CD44 molecule (Indian blood group) | 0.0186813 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0186558 |
| RAB7A | RAB7A, member RAS oncogene family | 0.018478 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0184434 |
| SEPTIN9 | septin 9 | 0.0181362 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0181257 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0180753 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.018019 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0177719 |
| RPL27 | ribosomal protein L27 | 0.017619 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0175639 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0174785 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0174697 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0173671 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0170048 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0167381 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0162903 |
| TJP1 | tight junction protein 1 | 0.0161568 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0161355 |
| PCDH1 | protocadherin 1 | 0.0161028 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0160986 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.015825 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0156433 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0154913 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0154161 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0153794 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.116058 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.10525 |
| TMSB10 | thymosin beta 10 | -0.103886 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0987102 |
| TMSB4X | thymosin beta 4, X-linked | -0.0940194 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0864775 |
| AHNAK | AHNAK nucleoprotein | -0.085062 |
| LAMB3 | laminin, beta 3 | -0.084802 |
| ANLN | anillin, actin binding protein | -0.0837952 |
| LMO7 | LIM domain 7 | -0.0832385 |
| CD2AP | CD2-associated protein | -0.0832343 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0807734 |
| LAMA4 | laminin, alpha 4 | -0.0799716 |
| MT2A | metallothionein 2A | -0.0794961 |
| EMP1 | epithelial membrane protein 1 | -0.0723682 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0714558 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0609416 |
| MYO6 | myosin VI | -0.0600276 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0577398 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.057206 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0562834 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0560172 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0555995 |
| JMJD1C | jumonji domain containing 1C | -0.0554801 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0552172 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0545212 |
| VCL | vinculin | -0.0538751 |
| MYOF | myoferlin | -0.0536386 |
| DIAPH3 | diaphanous-related formin 3 | -0.0529967 |
| EZR | ezrin | -0.0520219 |
| FRMD5 | FERM domain containing 5 | -0.0515209 |
| CANX | calnexin | -0.0510055 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0509683 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0505879 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0503322 |
| MKI67 | marker of proliferation Ki-67 | -0.0503255 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0502019 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0491286 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0477398 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0475304 |
| LAMC2 | laminin, gamma 2 | -0.0474703 |
| ACTN4 | actinin, alpha 4 | -0.0474346 |
| GOLGA4 | golgin A4 | -0.0468689 |
| RUNX1 | runt-related transcription factor 1 | -0.0451786 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0451665 |
| ASPH | aspartate beta-hydroxylase | -0.0440875 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0438619 |
| NF1 | neurofibromin 1 | -0.0431164 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0426997 |
| ECT2 | epithelial cell transforming 2 | -0.042499 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0424782 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0423047 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0417725 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0403557 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0398517 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0396072 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0386785 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0369973 |
| PLAT | plasminogen activator, tissue | -0.0365577 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0359258 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0358421 |
| HLA-B | major histocompatibility complex, class I, B | -0.0358142 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0357761 |
| DST | dystonin | -0.0352082 |
| RBM39 | RNA binding motif protein 39 | -0.0346034 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0345826 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0337214 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.033625 |
| PLAU | plasminogen activator, urokinase | -0.0334902 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0334147 |
| TMEM123 | transmembrane protein 123 | -0.0333924 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0328874 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0324616 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0324373 |
| SLTM | SAFB-like, transcription modulator | -0.0318003 |
| CD47 | CD47 molecule | -0.0315452 |
| CDK6 | cyclin-dependent kinase 6 | -0.0313942 |
| INHBA | inhibin, beta A | -0.0311308 |
| EPCAM | epithelial cell adhesion molecule | -0.0309712 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0309517 |
| MTAP | methylthioadenosine phosphorylase | -0.0306164 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0305451 |
| MT1X | metallothionein 1X | -0.0300999 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0299361 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.029439 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0294141 |
| OGA | O-GlcNAcase | -0.029308 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0287953 |
| TPI1 | triosephosphate isomerase 1 | -0.0284011 |
| RIOK3 | RIO kinase 3 | -0.028394 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0280461 |
| RASAL2 | RAS protein activator like 2 | -0.0276786 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0273806 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0272054 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0269864 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0269 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0265673 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0265245 |
| DEK | DEK proto-oncogene | -0.0262507 |
| MECOM | MDS1 and EVI1 complex locus | -0.026112 |
