| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.144614 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.141897 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.133134 |
| FLNB | filamin B, beta | 0.124547 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.12357 |
| PGK1 | phosphoglycerate kinase 1 | 0.111227 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.106042 |
| ACTG1 | actin gamma 1 | 0.0991779 |
| CD68 | CD68 molecule | 0.0875401 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0720096 |
| MT2A | metallothionein 2A | 0.0697862 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0658483 |
| HMGA1 | high mobility group AT-hook 1 | 0.0632586 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.061575 |
| PKM | pyruvate kinase, muscle | 0.0612463 |
| FRMD4A | FERM domain containing 4A | 0.059839 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0588116 |
| RASA2 | RAS p21 protein activator 2 | 0.0579665 |
| MCL1 | myeloid cell leukemia 1 | 0.0578422 |
| PTK2 | protein tyrosine kinase 2 | 0.0513238 |
| FLNA | filamin A, alpha | 0.0475634 |
| TMEM156 | transmembrane protein 156 | 0.0468306 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0464289 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0460327 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0457316 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0455283 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0454565 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0453992 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0439681 |
| TPD52 | tumor protein D52 | 0.0436577 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0436141 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0424143 |
| PARD3 | par-3 family cell polarity regulator | 0.0423096 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.042258 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.041969 |
| LDHA | lactate dehydrogenase A | 0.0402666 |
| NAV3 | neuron navigator 3 | 0.0399783 |
| FOSL1 | FOS-like antigen 1 | 0.0397093 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0394067 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0392395 |
| TMEM41B | transmembrane protein 41B | 0.0389182 |
| STC1 | stanniocalcin 1 | 0.0382806 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0379125 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0379059 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0377212 |
| CAPRIN2 | caprin family member 2 | 0.0371748 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0370936 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0367595 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0367223 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0362404 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0361402 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0353101 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.0343775 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0340401 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0337353 |
| ANK2 | ankyrin 2, neuronal | 0.0328805 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.032662 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0326163 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0322665 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0317203 |
| CDC27 | cell division cycle 27 | 0.0314626 |
| NUP58 | nucleoporin 58 | 0.0313015 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0308785 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0307442 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0307202 |
| CORO1C | coronin, actin binding protein, 1C | 0.0306987 |
| DGKI | diacylglycerol kinase, iota | 0.0305647 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0303027 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0302351 |
| YEATS2 | YEATS domain containing 2 | 0.0299823 |
| SRPK2 | SRSF protein kinase 2 | 0.0298545 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0297538 |
| RTN4 | reticulon 4 | 0.0297259 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0291093 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0289018 |
| PFN1 | profilin 1 | 0.0289015 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0287948 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0285606 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0282852 |
| AXL | AXL receptor tyrosine kinase | 0.0282352 |
| GSE1 | Gse1 coiled-coil protein | 0.0279968 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0279108 |
| ERBIN | erbb2 interacting protein | 0.0277831 |
| NAV2 | neuron navigator 2 | 0.0276506 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0276102 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0272877 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0269224 |
| RFX7 | regulatory factor X, 7 | 0.0266813 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0266311 |
| NDRG1 | N-myc downstream regulated 1 | 0.0266146 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0265852 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0265777 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0265116 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0262926 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.026289 |
| AFF1 | AF4/FMR2 family, member 1 | 0.026189 |
| RGMB | repulsive guidance molecule family member b | 0.0261711 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0259188 |
| BBX | bobby sox homolog (Drosophila) | 0.0255907 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0255814 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.191498 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.117937 |
| FRMD6 | FERM domain containing 6 | -0.100375 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0740843 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.074017 |
| RPS8 | ribosomal protein S8 | -0.0716612 |
| TMSB10 | thymosin beta 10 | -0.0711804 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0706213 |
| PTMA | prothymosin, alpha | -0.0626242 |
| RPL12 | ribosomal protein L12 | -0.0606171 |
| RPS24 | ribosomal protein S24 | -0.0567161 |
| MTAP | methylthioadenosine phosphorylase | -0.0551123 |
| RPL23 | ribosomal protein L23 | -0.0545455 |
| SP100 | SP100 nuclear antigen | -0.054189 |
| RPL7 | ribosomal protein L7 | -0.0537189 |
| AHNAK | AHNAK nucleoprotein | -0.0535442 |
| HMGA2 | high mobility group AT-hook 2 | -0.0527962 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0517812 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0507698 |
| INTS6 | integrator complex subunit 6 | -0.0490134 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0474344 |
| RPL7A | ribosomal protein L7a | -0.0466506 |
| RPL34 | ribosomal protein L34 | -0.0449734 |
| RPL5 | ribosomal protein L5 | -0.0434428 |
| NABP1 | nucleic acid binding protein 1 | -0.0434298 |
| CANX | calnexin | -0.0417862 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.03936 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0393563 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0391295 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.038944 |
| RPL19 | ribosomal protein L19 | -0.0381835 |
| RPL32 | ribosomal protein L32 | -0.0381461 |
| TTR | transthyretin | -0.0379564 |
| RPS6 | ribosomal protein S6 | -0.0368352 |
| RPL31 | ribosomal protein L31 | -0.0357451 |
| RPL26 | ribosomal protein L26 | -0.0344788 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0319046 |
| RPS27A | ribosomal protein S27a | -0.0311096 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.030571 |
| RPL37A | ribosomal protein L37a | -0.0304721 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0300782 |
| RPLP2 | ribosomal protein, large, P2 | -0.0299099 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.029834 |
| RPL35A | ribosomal protein L35a | -0.0295377 |
| AEBP2 | AE binding protein 2 | -0.0294851 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.028775 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0286928 |
| PHF3 | PHD finger protein 3 | -0.0286783 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0283202 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0282293 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0279887 |
| VCL | vinculin | -0.0277806 |
| RPS25 | ribosomal protein S25 | -0.0269278 |
| RPL10A | ribosomal protein L10a | -0.0266543 |
| ZNF438 | zinc finger protein 438 | -0.0258968 |
| RPS15 | ribosomal protein S15 | -0.0251465 |
| GDI2 | GDP dissociation inhibitor 2 | -0.0251215 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0250283 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0249988 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0248137 |
| RPS17 | ribosomal protein S17 | -0.024248 |
| RPS23 | ribosomal protein S23 | -0.0242226 |
| RPL9 | ribosomal protein L9 | -0.0242144 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0241561 |
| RPLP1 | ribosomal protein, large, P1 | -0.0241108 |
| RPS5 | ribosomal protein S5 | -0.0237607 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0236852 |
| MYRFL | myelin regulatory factor-like | -0.0235785 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0234337 |
| GOLGB1 | golgin B1 | -0.0232045 |
| MSH4 | mutS homolog 4 | -0.0229267 |
| DIAPH3 | diaphanous-related formin 3 | -0.0229225 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0227274 |
| RPL14 | ribosomal protein L14 | -0.0226047 |
| GPATCH2L | G patch domain containing 2-like | -0.0224755 |
| RPS14 | ribosomal protein S14 | -0.0222623 |
| YBX1 | Y box binding protein 1 | -0.0221271 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0221083 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0221081 |
| VIM | vimentin | -0.0218888 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0217979 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.021789 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0217499 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0216509 |
| ASPH | aspartate beta-hydroxylase | -0.0209789 |
| RIGI | RNA sensor RIG-I | -0.0207882 |
| SQSTM1 | sequestosome 1 | -0.0207247 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0207184 |
| RPS29 | ribosomal protein S29 | -0.0204332 |
| CCDC47 | coiled-coil domain containing 47 | -0.0203951 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0198282 |
| RPS21 | ribosomal protein S21 | -0.0196844 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0195636 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0194941 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0194634 |
| STK4 | serine/threonine kinase 4 | -0.0193804 |
| SGMS2 | sphingomyelin synthase 2 | -0.0193097 |
| MORF4L2 | mortality factor 4 like 2 | -0.019306 |
| CENPF | centromere protein F, 350/400kDa | -0.0192382 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0189682 |
