| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.256422 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.151918 |
| STC1 | stanniocalcin 1 | 0.134354 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.115174 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0761512 |
| NAV2 | neuron navigator 2 | 0.0713626 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0625479 |
| ANGPTL4 | angiopoietin-like 4 | 0.055231 |
| LOXL2 | lysyl oxidase-like 2 | 0.0544901 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0541694 |
| MMP2 | matrix metallopeptidase 2 | 0.0524665 |
| CD109 | CD109 molecule | 0.0487941 |
| TGM2 | transglutaminase 2 | 0.0455214 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0451599 |
| HMGA2 | high mobility group AT-hook 2 | 0.0447949 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0426174 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0421874 |
| ATP13A3 | ATPase type 13A3 | 0.0406505 |
| MMP12 | matrix metallopeptidase 12 | 0.0391428 |
| NDRG1 | N-myc downstream regulated 1 | 0.038569 |
| FOSL1 | FOS-like antigen 1 | 0.0382153 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0378983 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0378257 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0373491 |
| LDHA | lactate dehydrogenase A | 0.0370746 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0367733 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0360168 |
| FLNB | filamin B, beta | 0.0354849 |
| MYO1B | myosin IB | 0.0352186 |
| ANXA2 | annexin A2 | 0.0350236 |
| PGK1 | phosphoglycerate kinase 1 | 0.0342896 |
| MTSS1 | metastasis suppressor 1 | 0.0331156 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0330751 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0330532 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0329681 |
| ADM | adrenomedullin | 0.0303472 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0299993 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0296852 |
| SFTPA2 | surfactant protein A2 | 0.0291088 |
| FAT1 | FAT atypical cadherin 1 | 0.0289394 |
| HIP1 | huntingtin interacting protein 1 | 0.0281695 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0280677 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0268231 |
| ARRDC3 | arrestin domain containing 3 | 0.0263645 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0258815 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.025496 |
| SMAD3 | SMAD family member 3 | 0.0253577 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0251454 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0249678 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0246464 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0238175 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.023342 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0228261 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0228085 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0224351 |
| FBXO32 | F-box protein 32 | 0.0222903 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0222521 |
| MYOF | myoferlin | 0.0218821 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0215106 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0214384 |
| ECE1 | endothelin converting enzyme 1 | 0.0213749 |
| IL1B | interleukin 1, beta | 0.0210346 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0208084 |
| YEATS2 | YEATS domain containing 2 | 0.0207606 |
| OPTN | optineurin | 0.0201068 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0200544 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0197182 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0196925 |
| C1D | C1D nuclear receptor corepressor | 0.0195883 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0194066 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0193803 |
| LOX | lysyl oxidase | 0.0192488 |
| XPO1 | exportin 1 | 0.0191987 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0186834 |
| ANXA5 | annexin A5 | 0.0186356 |
| CCNL1 | cyclin L1 | 0.0185337 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0181778 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0176648 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0175971 |
| FLNA | filamin A, alpha | 0.0175887 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0175222 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0175081 |
| HLA-A | major histocompatibility complex, class I, A | 0.0174627 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0173546 |
| PLEC | plectin | 0.0171684 |
| JUN | jun proto-oncogene | 0.017163 |
| EGR1 | early growth response 1 | 0.0170942 |
| STK10 | serine/threonine kinase 10 | 0.0168222 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0165833 |
| PKM | pyruvate kinase, muscle | 0.0165603 |
| NRP1 | neuropilin 1 | 0.0165368 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0160267 |
| FHIT | fragile histidine triad | 0.0158947 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.015729 |
| IL6ST | interleukin 6 signal transducer | 0.0156613 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0155841 |
| KIAA1217 | KIAA1217 | 0.0155834 |
| HLA-E | major histocompatibility complex, class I, E | 0.015529 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0155187 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0154299 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.249087 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.147238 |
| TMSB10 | thymosin beta 10 | -0.11388 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.095532 |
| COL1A2 | collagen, type I, alpha 2 | -0.091074 |
| COL1A1 | collagen, type I, alpha 1 | -0.0909096 |
| CDH13 | cadherin 13 | -0.0848877 |
| FRMD4A | FERM domain containing 4A | -0.0769655 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0702783 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.063973 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0637696 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0604698 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0599448 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0575151 |
| SP100 | SP100 nuclear antigen | -0.0540184 |
| PTMA | prothymosin, alpha | -0.0524486 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0515303 |
| VCL | vinculin | -0.0433284 |
| ASPH | aspartate beta-hydroxylase | -0.0430901 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0428423 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.042667 |
| RRBP1 | ribosome binding protein 1 | -0.0411296 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0401505 |
| NAV1 | neuron navigator 1 | -0.0394595 |
| HDLBP | high density lipoprotein binding protein | -0.0388088 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0371958 |
| TMEM178B | transmembrane protein 178B | -0.036952 |
| ATXN1 | ataxin 1 | -0.0365688 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0351743 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0348686 |
| MAP4 | microtubule-associated protein 4 | -0.0341313 |
| DST | dystonin | -0.0318392 |
| TNS3 | tensin 3 | -0.03089 |
| VCAN | versican | -0.0305961 |
| AHNAK | AHNAK nucleoprotein | -0.0301289 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0296577 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0291581 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0281371 |
| ARF4 | ADP-ribosylation factor 4 | -0.0280178 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0279794 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0278985 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0277807 |
| LMNA | lamin A/C | -0.0277702 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0274196 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0274023 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0269651 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0262817 |
| RBM39 | RNA binding motif protein 39 | -0.0261729 |
| CENPF | centromere protein F, 350/400kDa | -0.0251133 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0249294 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0247976 |
| TPM4 | tropomyosin 4 | -0.0247513 |
| COL5A3 | collagen, type V, alpha 3 | -0.0246766 |
| CALR | calreticulin | -0.0245881 |
| IER3 | immediate early response 3 | -0.024493 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0239446 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0231035 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0228044 |
| ITGA1 | integrin, alpha 1 | -0.0227172 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0226252 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0224122 |
| S100A9 | S100 calcium binding protein A9 | -0.0223851 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0219876 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.021855 |
| PTK2 | protein tyrosine kinase 2 | -0.021516 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0215124 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0214997 |
| BICC1 | BicC family RNA binding protein 1 | -0.0214548 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0213287 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0212461 |
| SETD5 | SET domain containing 5 | -0.0212258 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0212117 |
| S100A10 | S100 calcium binding protein A10 | -0.0208615 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0208212 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0207815 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0207357 |
| RPS21 | ribosomal protein S21 | -0.0206964 |
| RPL31 | ribosomal protein L31 | -0.0206912 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0203554 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0202004 |
| HPCAL1 | hippocalcin-like 1 | -0.0199271 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0198966 |
| COL5A1 | collagen, type V, alpha 1 | -0.0198949 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0197284 |
| RPL28 | ribosomal protein L28 | -0.019644 |
| CANX | calnexin | -0.0194911 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.019428 |
| ATG7 | autophagy related 7 | -0.0193354 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0193311 |
| IFI44 | interferon-induced protein 44 | -0.0193101 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0192295 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0192123 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0189915 |
| SIK3 | SIK family kinase 3 | -0.0189762 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0189587 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.018805 |
| RPS17 | ribosomal protein S17 | -0.0188025 |
| VMP1 | vacuole membrane protein 1 | -0.0187791 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0186786 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | -0.0185147 |
