| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0731216 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0643198 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0568226 |
| VGF | VGF nerve growth factor inducible | 0.0564219 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0562056 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0518479 |
| EGR1 | early growth response 1 | 0.0508318 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | 0.0388528 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0378173 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0366079 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0365928 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0364258 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0355724 |
| MCL1 | myeloid cell leukemia 1 | 0.0352753 |
| SIK2 | salt-inducible kinase 2 | 0.0349708 |
| RASD1 | RAS, dexamethasone-induced 1 | 0.0348023 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.0341425 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0337413 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0327398 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0310124 |
| NTS | neurotensin | 0.0307626 |
| RNF144A | ring finger protein 144A | 0.0304784 |
| PFN1 | profilin 1 | 0.0303474 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.029917 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0276824 |
| STC1 | stanniocalcin 1 | 0.0271587 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0266499 |
| IRS2 | insulin receptor substrate 2 | 0.0245492 |
| TOX | thymocyte selection-associated high mobility group box | 0.0244694 |
| POTEF | POTE ankyrin domain family, member F | 0.0243925 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0241017 |
| NAV2 | neuron navigator 2 | 0.0234753 |
| RHOQ | ras homolog family member Q | 0.0227207 |
| MT2A | metallothionein 2A | 0.0224342 |
| FAT1 | FAT atypical cadherin 1 | 0.0223889 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0212887 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0209 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0201954 |
| GRAMD4 | GRAM domain containing 4 | 0.0201528 |
| DHFR | dihydrofolate reductase | 0.0200186 |
| CCNL1 | cyclin L1 | 0.0199471 |
| MT1X | metallothionein 1X | 0.0198853 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0195112 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0193344 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0189729 |
| INTS1 | integrator complex subunit 1 | 0.017983 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0173906 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0173658 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 | 0.0173261 |
| HMGB3 | high mobility group box 3 | 0.0172283 |
| MSN | moesin | 0.0172065 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0167182 |
| NANOS1 | nanos homolog 1 (Drosophila) | 0.0165077 |
| TCIM | transcriptional and immune response regulator | 0.0159692 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.0157466 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0156673 |
| LRATD1 | LRAT domain containing 1 | 0.0155721 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0155546 |
| TRAPPC12 | trafficking protein particle complex 12 | 0.0152115 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0152029 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0150812 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0150769 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0149452 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0148797 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0148609 |
| VEGFA | vascular endothelial growth factor A | 0.0147553 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0145882 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0144175 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0144091 |
| TMEM260 | transmembrane protein 260 | 0.0140729 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0140264 |
| PKM | pyruvate kinase, muscle | 0.0136297 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0131481 |
| NUP58 | nucleoporin 58 | 0.0130074 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0128182 |
| CD68 | CD68 molecule | 0.0127407 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0126336 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0125442 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.012524 |
| NNMT | nicotinamide N-methyltransferase | 0.0123597 |
| PER1 | period circadian clock 1 | 0.012298 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0121899 |
| HDGF | hepatoma-derived growth factor | 0.0121732 |
| CLEC16A | C-type lectin domain family 16, member A | 0.012124 |
| KLF9 | Kruppel-like factor 9 | 0.0120605 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0118266 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0116347 |
| PROX1 | prospero homeobox 1 | 0.0116042 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0115605 |
| DUSP12 | dual specificity phosphatase 12 | 0.0114364 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0114298 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0113797 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0112076 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | 0.0111584 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0110763 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.011001 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0109828 |
| CKB | creatine kinase, brain | 0.0108805 |
| SMYD2 | SET and MYND domain containing 2 | 0.0107877 |
| PUM3 | pumilio RNA binding family member 3 | 0.0106905 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.194905 |
| PTMA | prothymosin, alpha | -0.17639 |
| GPC6 | glypican 6 | -0.13017 |
| TENM1 | teneurin transmembrane protein 1 | -0.112602 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0980934 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0897297 |
| SMYD3 | SET and MYND domain containing 3 | -0.084705 |
| NRG1 | neuregulin 1 | -0.0845948 |
| RIT2 | Ras-like without CAAX 2 | -0.0713932 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0707916 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.067563 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0671594 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.066525 |
| SNTG1 | syntrophin, gamma 1 | -0.0662994 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0660851 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0607154 |
| TMSB4X | thymosin beta 4, X-linked | -0.0580358 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0578125 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0567595 |
| DTNA | dystrobrevin, alpha | -0.0543803 |
| RPL26 | ribosomal protein L26 | -0.0538704 |
| ESRRG | estrogen-related receptor gamma | -0.053561 |
| SYT1 | synaptotagmin I | -0.053017 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0521082 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.051472 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0510298 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.05099 |
| RPS27A | ribosomal protein S27a | -0.0506774 |
| GPC5 | glypican 5 | -0.0496406 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.047897 |
| CNKSR3 | CNKSR family member 3 | -0.0477485 |
| RPS8 | ribosomal protein S8 | -0.0477116 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0476907 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0465329 |
| CALCA | calcitonin-related polypeptide alpha | -0.0456207 |
| RORA | RAR-related orphan receptor A | -0.0451057 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0450515 |
| RPS21 | ribosomal protein S21 | -0.0441339 |
| RPS3 | ribosomal protein S3 | -0.0440034 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0436534 |
| ENO1 | enolase 1, (alpha) | -0.0433995 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0422914 |
| MATR3 | matrin 3 | -0.0421303 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0415919 |
| RPL23 | ribosomal protein L23 | -0.0412994 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0411216 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0407625 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0405137 |
| UBB | ubiquitin B | -0.0402791 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0399388 |
| ZNF292 | zinc finger protein 292 | -0.03974 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0389054 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0380456 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0379508 |
| CENPF | centromere protein F, 350/400kDa | -0.0374013 |
| CANX | calnexin | -0.0370566 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0366165 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.03642 |
| ACTG1 | actin gamma 1 | -0.0362601 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.0362283 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0360514 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0353827 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0352782 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0352315 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0352288 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0352225 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0351049 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0346924 |
| RPL11 | ribosomal protein L11 | -0.0340498 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0340388 |
| PRKD1 | protein kinase D1 | -0.0340223 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0339108 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0334754 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0331935 |
| S100A9 | S100 calcium binding protein A9 | -0.0331917 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0329726 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0326745 |
| RPL32 | ribosomal protein L32 | -0.0324643 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0322128 |
| FUS | FUS RNA binding protein | -0.0320957 |
| RPL38 | ribosomal protein L38 | -0.0320626 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0320366 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0318011 |
| OGA | O-GlcNAcase | -0.031527 |
| EFNA5 | ephrin-A5 | -0.0315192 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.031299 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0312224 |
| MED13L | mediator complex subunit 13-like | -0.0311849 |
| RPL37A | ribosomal protein L37a | -0.0310532 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0309755 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0308121 |
| FOXC1 | forkhead box C1 | -0.0306168 |
| TPD52 | tumor protein D52 | -0.0302737 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0302668 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0301844 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0300973 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0299489 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0298171 |
| MSI2 | musashi RNA-binding protein 2 | -0.0297863 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0295779 |
