| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PKM | pyruvate kinase, muscle | 0.181344 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.14198 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.10706 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0855525 |
| BMP10 | bone morphogenetic protein 10 | 0.0749223 |
| PGK1 | phosphoglycerate kinase 1 | 0.0623896 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0575729 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0554487 |
| PYGB | phosphorylase, glycogen; brain | 0.0522862 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0499902 |
| LDHA | lactate dehydrogenase A | 0.0474641 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0457061 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0432697 |
| TJP1 | tight junction protein 1 | 0.0401928 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0362772 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0333269 |
| CCNL1 | cyclin L1 | 0.0330274 |
| FAM13A | family with sequence similarity 13, member A | 0.0328666 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0308789 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0306635 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0303961 |
| LOXL3 | lysyl oxidase-like 3 | 0.0292914 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0289985 |
| RPS2 | ribosomal protein S2 | 0.028609 |
| FLNB | filamin B, beta | 0.0285718 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0284724 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0278396 |
| GSE1 | Gse1 coiled-coil protein | 0.0269905 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.026677 |
| OSMR | oncostatin M receptor | 0.0263049 |
| TOB1 | transducer of ERBB2, 1 | 0.0262135 |
| HMGA1 | high mobility group AT-hook 1 | 0.0259209 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0252086 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0251258 |
| ENOSF1 | enolase superfamily member 1 | 0.0243813 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.024077 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0238448 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.023456 |
| YEATS2 | YEATS domain containing 2 | 0.0231847 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0229883 |
| TRERF1 | transcriptional regulating factor 1 | 0.0229382 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0228864 |
| NONO | non-POU domain containing, octamer-binding | 0.0227596 |
| TRIM24 | tripartite motif containing 24 | 0.0221639 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0220394 |
| MYO5C | myosin VC | 0.0214189 |
| PDGFC | platelet derived growth factor C | 0.0213106 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.021252 |
| LDHB | lactate dehydrogenase B | 0.0210141 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0204555 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0202715 |
| TLK1 | tousled-like kinase 1 | 0.0197893 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.019656 |
| THBD | thrombomodulin | 0.0196047 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0194663 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0191922 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0191893 |
| TXNIP | thioredoxin interacting protein | 0.0189827 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.01837 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0182332 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0177615 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0177195 |
| PTMS | parathymosin | 0.0176094 |
| HJURP | Holliday junction recognition protein | 0.0174454 |
| KIF5B | kinesin family member 5B | 0.0174245 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0173572 |
| ZNF91 | zinc finger protein 91 | 0.0173036 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0172822 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0172029 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0171353 |
| NUP58 | nucleoporin 58 | 0.0169574 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0169481 |
| TXNRD1 | thioredoxin reductase 1 | 0.0169295 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0169048 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.016861 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0167887 |
| EMP3 | epithelial membrane protein 3 | 0.0166167 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0165676 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0165637 |
| AMOTL2 | angiomotin like 2 | 0.0165287 |
| CCND1 | cyclin D1 | 0.0165036 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0164864 |
| RHOA | ras homolog family member A | 0.0164376 |
| LIX1L | Lix1 homolog (chicken) like | 0.0164087 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0163848 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0163408 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0162992 |
| NBAS | neuroblastoma amplified sequence | 0.016255 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0160587 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0160248 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0159699 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0157565 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0157504 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0157331 |
| TNPO3 | transportin 3 | 0.0155066 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0154225 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.015248 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0152276 |
| TMEM65 | transmembrane protein 65 | 0.0152074 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0151675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.239592 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.183253 |
| PTMA | prothymosin, alpha | -0.153978 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.139129 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.133762 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.116361 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.104923 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0987971 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0701303 |
| FOXP1 | forkhead box P1 | -0.0627343 |
| RPS19 | ribosomal protein S19 | -0.0609052 |
| RPL35A | ribosomal protein L35a | -0.0607252 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0581092 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0534258 |
| TMSB4X | thymosin beta 4, X-linked | -0.0531882 |
| RPL34 | ribosomal protein L34 | -0.0526365 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0521509 |
| TMSB10 | thymosin beta 10 | -0.0506333 |
| INTS6 | integrator complex subunit 6 | -0.0505272 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0499751 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0485399 |
| RPL11 | ribosomal protein L11 | -0.0482928 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0482679 |
| RPL31 | ribosomal protein L31 | -0.0478284 |
| RPL12 | ribosomal protein L12 | -0.0475529 |
| RPL32 | ribosomal protein L32 | -0.0466277 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0451483 |
| PTK2 | protein tyrosine kinase 2 | -0.0449832 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0447054 |
| JMJD1C | jumonji domain containing 1C | -0.042917 |
| RPS6 | ribosomal protein S6 | -0.0428493 |
| EXT1 | exostosin glycosyltransferase 1 | -0.041956 |
| RPL19 | ribosomal protein L19 | -0.0419045 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0418164 |
| RPS23 | ribosomal protein S23 | -0.0417896 |
| RBM39 | RNA binding motif protein 39 | -0.0415462 |
| RPL23 | ribosomal protein L23 | -0.0414047 |
| RPS8 | ribosomal protein S8 | -0.0406475 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0404766 |
| FN1 | fibronectin 1 | -0.0403012 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0401988 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0394242 |
| EFNA5 | ephrin-A5 | -0.0393103 |
| RPL5 | ribosomal protein L5 | -0.0392875 |
| GPHN | gephyrin | -0.0389357 |
| RPS12 | ribosomal protein S12 | -0.0386384 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0386054 |
| AEBP2 | AE binding protein 2 | -0.0383468 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0374658 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0365093 |
| RPS24 | ribosomal protein S24 | -0.0361582 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0357313 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0353757 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0352751 |
| RPL7A | ribosomal protein L7a | -0.0346424 |
| AHNAK | AHNAK nucleoprotein | -0.0345755 |
| RPS25 | ribosomal protein S25 | -0.0345165 |
| FER1L6 | fer-1-like family member 6 | -0.0341829 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0341425 |
| RPS3 | ribosomal protein S3 | -0.0338506 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0333667 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0324807 |
| CLIC4 | chloride intracellular channel 4 | -0.0323349 |
| S100A9 | S100 calcium binding protein A9 | -0.0319442 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0315995 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0313538 |
| RPS15 | ribosomal protein S15 | -0.0310853 |
| RPS11 | ribosomal protein S11 | -0.0309599 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.030853 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0306487 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0303768 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0303741 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0301925 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0301843 |
| RPL26 | ribosomal protein L26 | -0.0301091 |
| RPS16 | ribosomal protein S16 | -0.0299452 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.02851 |
| RPLP2 | ribosomal protein, large, P2 | -0.0282503 |
| ANXA1 | annexin A1 | -0.028124 |
| ANK2 | ankyrin 2, neuronal | -0.0280067 |
| RPS27A | ribosomal protein S27a | -0.0278324 |
| FNIP1 | folliculin interacting protein 1 | -0.0277817 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0273012 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0272155 |
| PHF3 | PHD finger protein 3 | -0.0271587 |
| RPL8 | ribosomal protein L8 | -0.0271323 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0270568 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0262916 |
| VIM | vimentin | -0.0261654 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0261575 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0260559 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.025629 |
| MORF4L2 | mortality factor 4 like 2 | -0.025538 |
| MSI2 | musashi RNA-binding protein 2 | -0.0254211 |
| S100A6 | S100 calcium binding protein A6 | -0.0249265 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.024859 |
| FUS | FUS RNA binding protein | -0.0246695 |
| BPTF | bromodomain PHD finger transcription factor | -0.0246018 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0245872 |
| PDE7B | phosphodiesterase 7B | -0.0244322 |
