| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.213233 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.170474 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.142602 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.134736 |
| PGK1 | phosphoglycerate kinase 1 | 0.132269 |
| LDHA | lactate dehydrogenase A | 0.118009 |
| NDRG1 | N-myc downstream regulated 1 | 0.11254 |
| COL6A3 | collagen, type VI, alpha 3 | 0.110555 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.108574 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0924038 |
| NAV2 | neuron navigator 2 | 0.0922524 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0879933 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.08211 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0739483 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0719741 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0672254 |
| HMGA2 | high mobility group AT-hook 2 | 0.0660624 |
| PKM | pyruvate kinase, muscle | 0.0650613 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.060894 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0569308 |
| VEGFA | vascular endothelial growth factor A | 0.0569035 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0553857 |
| FLNA | filamin A, alpha | 0.0536172 |
| STC1 | stanniocalcin 1 | 0.0523096 |
| CCNL1 | cyclin L1 | 0.0516685 |
| FLNB | filamin B, beta | 0.0501795 |
| EFNA5 | ephrin-A5 | 0.0496801 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0485464 |
| TGM2 | transglutaminase 2 | 0.0476351 |
| SFTPA2 | surfactant protein A2 | 0.0473058 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0465284 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0463718 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0461731 |
| SEPTIN9 | septin 9 | 0.046054 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0454342 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0453794 |
| CD44 | CD44 molecule (Indian blood group) | 0.0449919 |
| COL5A1 | collagen, type V, alpha 1 | 0.0441083 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0416412 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.04111 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0406648 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0403335 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0398741 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0390606 |
| C3 | complement component 3 | 0.0385393 |
| MCL1 | myeloid cell leukemia 1 | 0.0379247 |
| HMGA1 | high mobility group AT-hook 1 | 0.0377242 |
| PHF21A | PHD finger protein 21A | 0.0375403 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0370923 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0369553 |
| FBXO32 | F-box protein 32 | 0.0353014 |
| CD68 | CD68 molecule | 0.0349997 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0337524 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0334918 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0332121 |
| PLIN2 | perilipin 2 | 0.0328127 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0325143 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0319491 |
| ADM | adrenomedullin | 0.0315626 |
| TRAM2 | translocation associated membrane protein 2 | 0.0315177 |
| EGFR | epidermal growth factor receptor | 0.0314189 |
| ARRDC3 | arrestin domain containing 3 | 0.0313299 |
| CDK19 | cyclin-dependent kinase 19 | 0.0312034 |
| NAV1 | neuron navigator 1 | 0.0311835 |
| VCAN | versican | 0.0309672 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0304233 |
| FAM13A | family with sequence similarity 13, member A | 0.0302048 |
| ENO1 | enolase 1, (alpha) | 0.0299119 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0298556 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0298285 |
| MMP2 | matrix metallopeptidase 2 | 0.0295586 |
| BRD2 | bromodomain containing 2 | 0.0295395 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0293358 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0288372 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0286973 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.028686 |
| YEATS2 | YEATS domain containing 2 | 0.0285305 |
| LOXL2 | lysyl oxidase-like 2 | 0.0285222 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0283839 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0277427 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0275541 |
| MYOF | myoferlin | 0.0274229 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | 0.0273887 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0268882 |
| TNS3 | tensin 3 | 0.026657 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0265333 |
| ASPH | aspartate beta-hydroxylase | 0.0257538 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.025326 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0252479 |
| LOX | lysyl oxidase | 0.0249123 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0248515 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0247573 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0247506 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0245432 |
| C1D | C1D nuclear receptor corepressor | 0.0244686 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0243735 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0242352 |
| CTSA | cathepsin A | 0.0240568 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0237585 |
| NONO | non-POU domain containing, octamer-binding | 0.0237523 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.224954 |
| VCL | vinculin | -0.124071 |
| TMSB10 | thymosin beta 10 | -0.123791 |
| FRMD4A | FERM domain containing 4A | -0.122213 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.115363 |
| FTL | ferritin, light polypeptide | -0.10072 |
| IER3 | immediate early response 3 | -0.0941408 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0837809 |
| PTMA | prothymosin, alpha | -0.0637564 |
| RPS24 | ribosomal protein S24 | -0.0611973 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0598322 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0569983 |
| BICC1 | BicC family RNA binding protein 1 | -0.055535 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0550528 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0549747 |
| AHNAK | AHNAK nucleoprotein | -0.0528155 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0518634 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0512643 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0497006 |
| TMSB4X | thymosin beta 4, X-linked | -0.0495529 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0493065 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0472075 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0469125 |
| RIGI | RNA sensor RIG-I | -0.0461041 |
| KYNU | kynureninase | -0.0460508 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0432032 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0430559 |
| RPL19 | ribosomal protein L19 | -0.0409209 |
| MT2A | metallothionein 2A | -0.0402836 |
| MORF4L2 | mortality factor 4 like 2 | -0.0402158 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0401132 |
| RPS3 | ribosomal protein S3 | -0.0396268 |
| FRMD5 | FERM domain containing 5 | -0.0391785 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0381746 |
| OGA | O-GlcNAcase | -0.0374112 |
| RPL32 | ribosomal protein L32 | -0.0366395 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0351762 |
| CADM1 | cell adhesion molecule 1 | -0.0351204 |
| NABP1 | nucleic acid binding protein 1 | -0.0342037 |
| PALLD | palladin, cytoskeletal associated protein | -0.0339338 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0338241 |
| RPL12 | ribosomal protein L12 | -0.0330258 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0326002 |
| RPL26 | ribosomal protein L26 | -0.0323548 |
| SBF2 | SET binding factor 2 | -0.0322174 |
| HLA-B | major histocompatibility complex, class I, B | -0.0322155 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0321558 |
| RPS12 | ribosomal protein S12 | -0.0306759 |
| SP100 | SP100 nuclear antigen | -0.0306183 |
| RPS8 | ribosomal protein S8 | -0.0291401 |
| CALD1 | caldesmon 1 | -0.0283886 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0282083 |
| CLIC4 | chloride intracellular channel 4 | -0.0280354 |
| THBS1 | thrombospondin 1 | -0.027851 |
| QKI | QKI, KH domain containing, RNA binding | -0.0272353 |
| RPL36A | ribosomal protein L36a | -0.0271813 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.027082 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0267937 |
| RPL31 | ribosomal protein L31 | -0.0266511 |
| TXNRD1 | thioredoxin reductase 1 | -0.0266466 |
| RRBP1 | ribosome binding protein 1 | -0.0266145 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0262185 |
| UBC | ubiquitin C | -0.0258512 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0254853 |
| CANX | calnexin | -0.025479 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0253793 |
| EHBP1 | EH domain binding protein 1 | -0.0253497 |
| NCKAP5 | NCK-associated protein 5 | -0.0253024 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0252491 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0249268 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0246841 |
| GOLGA3 | golgin A3 | -0.0242575 |
| RPL34 | ribosomal protein L34 | -0.024177 |
| MAP4 | microtubule-associated protein 4 | -0.0240154 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0239916 |
| RPL14 | ribosomal protein L14 | -0.023957 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.023793 |
| RPLP2 | ribosomal protein, large, P2 | -0.0237117 |
| RTN4 | reticulon 4 | -0.0235017 |
| GOLGB1 | golgin B1 | -0.0233717 |
| COL1A1 | collagen, type I, alpha 1 | -0.0232966 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0232841 |
| RPS27A | ribosomal protein S27a | -0.0231441 |
| RPLP1 | ribosomal protein, large, P1 | -0.0227188 |
| ANXA2 | annexin A2 | -0.0227019 |
| SERINC1 | serine incorporator 1 | -0.0224682 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0222474 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0222273 |
| SERINC3 | serine incorporator 3 | -0.0220962 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0218272 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0217955 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0215785 |
| TRIM55 | tripartite motif containing 55 | -0.0215418 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0212512 |
| SMAD2 | SMAD family member 2 | -0.0212105 |
| RBM39 | RNA binding motif protein 39 | -0.0211247 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0209025 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0208549 |
| NF1 | neurofibromin 1 | -0.0206952 |
| GNAS | GNAS complex locus | -0.0206598 |
