| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.225196 |
| FN1 | fibronectin 1 | 0.160438 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.129879 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.102408 |
| LOX | lysyl oxidase | 0.0996378 |
| EGFR | epidermal growth factor receptor | 0.0869222 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0829906 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0818732 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0810984 |
| HMGA2 | high mobility group AT-hook 2 | 0.0778418 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0771485 |
| TNS3 | tensin 3 | 0.0653755 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0640853 |
| HIP1 | huntingtin interacting protein 1 | 0.0591513 |
| MAP1B | microtubule-associated protein 1B | 0.0585421 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0561146 |
| ADM | adrenomedullin | 0.0520504 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0503541 |
| FLNA | filamin A, alpha | 0.0501212 |
| PKM | pyruvate kinase, muscle | 0.0483243 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0480874 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.047692 |
| ECE1 | endothelin converting enzyme 1 | 0.0470285 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0467327 |
| POTEF | POTE ankyrin domain family, member F | 0.0449386 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.042545 |
| ARRDC3 | arrestin domain containing 3 | 0.0420786 |
| LOXL2 | lysyl oxidase-like 2 | 0.0415273 |
| SRPK2 | SRSF protein kinase 2 | 0.0411936 |
| GLG1 | golgi glycoprotein 1 | 0.0395938 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0392745 |
| PGK1 | phosphoglycerate kinase 1 | 0.0391938 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0391758 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0385903 |
| ZFHX3 | zinc finger homeobox 3 | 0.0372854 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0365486 |
| EXOC4 | exocyst complex component 4 | 0.036151 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0360631 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0351817 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0345251 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0341899 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0335721 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0334523 |
| GOLGB1 | golgin B1 | 0.033433 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0328095 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0323586 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0322348 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0319192 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0317828 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0311149 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0302781 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0302748 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0300551 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0299181 |
| ACTG1 | actin gamma 1 | 0.0298856 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0295036 |
| MYADM | myeloid-associated differentiation marker | 0.0294793 |
| COG6 | component of oligomeric golgi complex 6 | 0.0293255 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0291731 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0289755 |
| APP | amyloid beta (A4) precursor protein | 0.0289266 |
| AOPEP | aminopeptidase O (putative) | 0.0287239 |
| MTDH | metadherin | 0.0285444 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.028496 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0284392 |
| PHF14 | PHD finger protein 14 | 0.0282105 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0281611 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0281423 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0281018 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0277534 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0273349 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0271886 |
| MTMR3 | myotubularin related protein 3 | 0.0270799 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0268787 |
| CDK6 | cyclin-dependent kinase 6 | 0.0268197 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.026732 |
| ENO1 | enolase 1, (alpha) | 0.026555 |
| EFNA5 | ephrin-A5 | 0.0264706 |
| TLN1 | talin 1 | 0.0264698 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0262876 |
| OSMR | oncostatin M receptor | 0.0261702 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0261491 |
| TRERF1 | transcriptional regulating factor 1 | 0.026067 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0259127 |
| FAM20C | family with sequence similarity 20, member C | 0.0258464 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0258202 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0250623 |
| LASP1 | LIM and SH3 protein 1 | 0.0249904 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0248825 |
| PRMT2 | protein arginine methyltransferase 2 | 0.0248451 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0246237 |
| CCND1 | cyclin D1 | 0.0245716 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0245457 |
| SYNPO | synaptopodin | 0.0245313 |
| SP4 | Sp4 transcription factor | 0.0243608 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0243171 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | 0.024312 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.024154 |
| FAM120A | family with sequence similarity 120A | 0.0241467 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0240536 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.248294 |
| TMSB10 | thymosin beta 10 | -0.142931 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.109692 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0976667 |
| ATP13A3 | ATPase type 13A3 | -0.0819646 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0714363 |
| COL1A2 | collagen, type I, alpha 2 | -0.0656466 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0620364 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0615388 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0543545 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.054232 |
| VIM | vimentin | -0.0540614 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.052293 |
| UBC | ubiquitin C | -0.051966 |
| CADM1 | cell adhesion molecule 1 | -0.0511078 |
| PTMA | prothymosin, alpha | -0.0507251 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0503498 |
| CALD1 | caldesmon 1 | -0.0490684 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0485037 |
| COL1A1 | collagen, type I, alpha 1 | -0.0476767 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0471727 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0470373 |
| LMNA | lamin A/C | -0.0451705 |
| H3-3B | H3.3 histone B | -0.0447245 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0445732 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0445103 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0442562 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0439143 |
| CANX | calnexin | -0.0433433 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0402917 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0402108 |
| SDC4 | syndecan 4 | -0.0400218 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0399491 |
| FRMD4A | FERM domain containing 4A | -0.0397228 |
| CLIC4 | chloride intracellular channel 4 | -0.0386645 |
| S100A9 | S100 calcium binding protein A9 | -0.0383983 |
| MT2A | metallothionein 2A | -0.0381836 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0380905 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0379558 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.03701 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0368436 |
| FTL | ferritin, light polypeptide | -0.0365876 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0360049 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0354945 |
| SEC24D | SEC24 family member D | -0.0354721 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.03507 |
| HMGB2 | high mobility group box 2 | -0.0347508 |
| GLIS3 | GLIS family zinc finger 3 | -0.0347062 |
| RPL37A | ribosomal protein L37a | -0.0344548 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0343982 |
| PRELID2 | PRELI domain containing 2 | -0.0339282 |
| OGA | O-GlcNAcase | -0.0336941 |
| CLINT1 | clathrin interactor 1 | -0.0336562 |
| ATP11B | ATPase, class VI, type 11B | -0.0336405 |
| DYM | dymeclin | -0.033585 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0332623 |
| TMSB4X | thymosin beta 4, X-linked | -0.0332564 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0325935 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0323034 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.031866 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0316504 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0313769 |
| NOP58 | NOP58 ribonucleoprotein | -0.031281 |
| RACK1 | receptor for activated C kinase 1 | -0.0311943 |
| MATR3 | matrin 3 | -0.0311546 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0309465 |
| CALR | calreticulin | -0.0309123 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0307713 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0306322 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.030439 |
| TPD52 | tumor protein D52 | -0.0300133 |
| RPS12 | ribosomal protein S12 | -0.0299413 |
| RASA3 | RAS p21 protein activator 3 | -0.029858 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0297646 |
| JAG1 | jagged 1 | -0.0295713 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0294463 |
| TFG | TRK-fused gene | -0.0294432 |
| AHNAK | AHNAK nucleoprotein | -0.0289435 |
| BMERB1 | bMERB domain containing 1 | -0.0287049 |
| COLEC11 | collectin sub-family member 11 | -0.0286574 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0283631 |
| DENND4C | DENN/MADD domain containing 4C | -0.0282874 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.0278705 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0275352 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0274392 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0274227 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0274206 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.027276 |
| RPL28 | ribosomal protein L28 | -0.0268948 |
| VCL | vinculin | -0.0268141 |
| TMEM41B | transmembrane protein 41B | -0.0261428 |
| FNDC3B | fibronectin type III domain containing 3B | -0.025941 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0257572 |
| WTAP | Wilms tumor 1 associated protein | -0.0257198 |
| ANO10 | anoctamin 10 | -0.0256875 |
| POT1 | protection of telomeres 1 | -0.0254718 |
| GOLGA4 | golgin A4 | -0.0254688 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0254246 |
| RPL31 | ribosomal protein L31 | -0.0252101 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0251482 |
