| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0917419 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0821724 |
| ANGPTL4 | angiopoietin-like 4 | 0.070655 |
| LDHA | lactate dehydrogenase A | 0.0699689 |
| DNER | delta/notch-like EGF repeat containing | 0.0642845 |
| TGM2 | transglutaminase 2 | 0.0620568 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0591441 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0521667 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0508226 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0506564 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0501915 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0456849 |
| MT2A | metallothionein 2A | 0.0407024 |
| TXNIP | thioredoxin interacting protein | 0.0402898 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0392014 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0391578 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0373978 |
| FKBP5 | FK506 binding protein 5 | 0.0361676 |
| CCNL1 | cyclin L1 | 0.0354193 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0344705 |
| FLNA | filamin A, alpha | 0.0343899 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0327786 |
| RPL4 | ribosomal protein L4 | 0.0307238 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0296118 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0284399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0279914 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0277997 |
| PER1 | period circadian clock 1 | 0.0276595 |
| PKM | pyruvate kinase, muscle | 0.0270302 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0268564 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0267858 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0267456 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0265539 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0264963 |
| HPCAL1 | hippocalcin-like 1 | 0.0263551 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0256778 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0255115 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0251179 |
| DUSP12 | dual specificity phosphatase 12 | 0.0249109 |
| ATP13A3 | ATPase type 13A3 | 0.0244343 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0240987 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.02389 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0238395 |
| KLF9 | Kruppel-like factor 9 | 0.0236273 |
| FLNB | filamin B, beta | 0.0234204 |
| CD44 | CD44 molecule (Indian blood group) | 0.0234193 |
| FMNL2 | formin-like 2 | 0.0227853 |
| EXOC6B | exocyst complex component 6B | 0.0224851 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0224159 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0222945 |
| BCL2L1 | BCL2-like 1 | 0.0217977 |
| B2M | beta-2-microglobulin | 0.0216671 |
| MTCH1 | mitochondrial carrier 1 | 0.0211527 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0210604 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0209628 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0209461 |
| NPTN | neuroplastin | 0.0208089 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0207802 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0207342 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa | 0.0206372 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0205265 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0203162 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0201447 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0198538 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.019717 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0194225 |
| ATXN7 | ataxin 7 | 0.0193119 |
| RBM33 | RNA binding motif protein 33 | 0.019278 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.0189099 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0188841 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.0188362 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0188051 |
| OSMR | oncostatin M receptor | 0.0187831 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0186628 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0186112 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0185953 |
| HIPK1 | homeodomain interacting protein kinase 1 | 0.0185891 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0185795 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.0185479 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0185387 |
| CUL2 | cullin 2 | 0.0185361 |
| CCND3 | cyclin D3 | 0.0184762 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0183236 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0183051 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0181151 |
| LARP4 | La ribonucleoprotein domain family, member 4 | 0.0180597 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0180141 |
| ZNF148 | zinc finger protein 148 | 0.0179735 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.01795 |
| MTPN | myotrophin | 0.0178575 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0177852 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0177208 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0176144 |
| FKBP15 | FK506 binding protein 15, 133kDa | 0.0176133 |
| FN1 | fibronectin 1 | 0.017583 |
| FOSL2 | FOS-like antigen 2 | 0.0175803 |
| POTEF | POTE ankyrin domain family, member F | 0.0174748 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.017452 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0173483 |
| WDR27 | WD repeat domain 27 | 0.0173472 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.158625 |
| TMSB10 | thymosin beta 10 | -0.142267 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.137007 |
| DST | dystonin | -0.113087 |
| PTMA | prothymosin, alpha | -0.0947081 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0850918 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.080468 |
| ATXN1 | ataxin 1 | -0.0769153 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0691307 |
| IER3 | immediate early response 3 | -0.0659585 |
| HMGA2 | high mobility group AT-hook 2 | -0.063022 |
| PRKCA | protein kinase C, alpha | -0.0623341 |
| RSF1 | remodeling and spacing factor 1 | -0.0614791 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0593857 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0589324 |
| CANX | calnexin | -0.0583338 |
| OGA | O-GlcNAcase | -0.0567776 |
| AHNAK | AHNAK nucleoprotein | -0.0565497 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0524917 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0499906 |
| SNX14 | sorting nexin 14 | -0.0496065 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0469081 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0467227 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0463538 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0463014 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0462047 |
| DTNA | dystrobrevin, alpha | -0.0459205 |
| PARD3 | par-3 family cell polarity regulator | -0.0455405 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0455192 |
| RAD51B | RAD51 paralog B | -0.0451923 |
| PRSS23 | protease, serine, 23 | -0.0451359 |
| VCL | vinculin | -0.0432404 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0424814 |
| GPC6 | glypican 6 | -0.041492 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.041448 |
| TCF12 | transcription factor 12 | -0.04073 |
| RPLP1 | ribosomal protein, large, P1 | -0.0403745 |
| ZNF609 | zinc finger protein 609 | -0.0402804 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0396279 |
| RAI14 | retinoic acid induced 14 | -0.0394086 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0391649 |
| CDK6 | cyclin-dependent kinase 6 | -0.0388149 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0387399 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0386611 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0386222 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0384957 |
| NAV2 | neuron navigator 2 | -0.0380688 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0380609 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0373314 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0372882 |
| ATM | ATM serine/threonine kinase | -0.0365778 |
| LMO7 | LIM domain 7 | -0.036576 |
| RBM39 | RNA binding motif protein 39 | -0.036224 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0356338 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.035506 |
| PTK2 | protein tyrosine kinase 2 | -0.0352828 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0352732 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0351824 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0351004 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0348664 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0346389 |
| ERBIN | erbb2 interacting protein | -0.0343195 |
| MEF2A | myocyte enhancer factor 2A | -0.0340487 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0336244 |
| NGLY1 | N-glycanase 1 | -0.0332566 |
| FUS | FUS RNA binding protein | -0.0330117 |
| ATG7 | autophagy related 7 | -0.0327951 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0326972 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0326089 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.032419 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0324003 |
| SMYD3 | SET and MYND domain containing 3 | -0.0322191 |
| GOLGA4 | golgin A4 | -0.0320796 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0318778 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0317872 |
| PCED1B | PC-esterase domain containing 1B | -0.0313125 |
| TPX2 | TPX2, microtubule-associated | -0.0311909 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0311023 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0307866 |
| SDC4 | syndecan 4 | -0.0307275 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0303547 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0303187 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0302455 |
| GNAS | GNAS complex locus | -0.0299912 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0295324 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0294473 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0292997 |
| NAV3 | neuron navigator 3 | -0.0292429 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0291849 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.029157 |
| WAC | WW domain containing adaptor with coiled-coil | -0.029114 |
| PDE8A | phosphodiesterase 8A | -0.0290738 |
| TPM4 | tropomyosin 4 | -0.028953 |
| CCNH | cyclin H | -0.0285979 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0284476 |
| ANO6 | anoctamin 6 | -0.0283641 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0283622 |
| UTRN | utrophin | -0.0281861 |
| FTL | ferritin, light polypeptide | -0.0280702 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0280586 |
