| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.293828 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0864266 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0612287 |
| NRG1 | neuregulin 1 | 0.0610186 |
| PGK1 | phosphoglycerate kinase 1 | 0.0595318 |
| HMGA2 | high mobility group AT-hook 2 | 0.0570434 |
| NDRG1 | N-myc downstream regulated 1 | 0.052757 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0519492 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0494918 |
| B2M | beta-2-microglobulin | 0.0476682 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0475171 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0433899 |
| PKM | pyruvate kinase, muscle | 0.0432703 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0417128 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0408107 |
| SFTPA2 | surfactant protein A2 | 0.0405301 |
| IGF2 | insulin-like growth factor 2 | 0.0397515 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0396369 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0394165 |
| FAM13A | family with sequence similarity 13, member A | 0.0392081 |
| ENO1 | enolase 1, (alpha) | 0.0379045 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0360701 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0358575 |
| PLIN2 | perilipin 2 | 0.0358346 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0357789 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0357466 |
| MCL1 | myeloid cell leukemia 1 | 0.034156 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0331597 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0326013 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0320065 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0316574 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0315526 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0305535 |
| ACTG1 | actin gamma 1 | 0.0302624 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0298324 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0289668 |
| DUSP6 | dual specificity phosphatase 6 | 0.0287933 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0283241 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0271362 |
| STC2 | stanniocalcin 2 | 0.026441 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0256251 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0248988 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0238966 |
| GLUL | glutamate-ammonia ligase | 0.0238566 |
| ITGB4 | integrin, beta 4 | 0.0229125 |
| MYOF | myoferlin | 0.0227688 |
| HLA-A | major histocompatibility complex, class I, A | 0.0226509 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0225564 |
| EFNA5 | ephrin-A5 | 0.0224755 |
| NCOR2 | nuclear receptor corepressor 2 | 0.022396 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0216723 |
| FLNB | filamin B, beta | 0.0207985 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0207635 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0206488 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0203469 |
| FLNA | filamin A, alpha | 0.0202348 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0201294 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0201284 |
| MYADM | myeloid-associated differentiation marker | 0.0198725 |
| CD109 | CD109 molecule | 0.0197298 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0191434 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0190808 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0190248 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0188866 |
| CALR | calreticulin | 0.0186578 |
| FRY | furry homolog (Drosophila) | 0.0185854 |
| POTEF | POTE ankyrin domain family, member F | 0.0183544 |
| FOSL1 | FOS-like antigen 1 | 0.018135 |
| CTSD | cathepsin D | 0.0178921 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0178061 |
| NEBL | nebulette | 0.0176309 |
| IL6 | interleukin 6 | 0.0173593 |
| MNT | MAX network transcriptional repressor | 0.0173433 |
| RAD51B | RAD51 paralog B | 0.0170215 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.016958 |
| ANXA5 | annexin A5 | 0.0165677 |
| TMEM65 | transmembrane protein 65 | 0.016441 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0163184 |
| TGM2 | transglutaminase 2 | 0.0161565 |
| ARFGEF3 | ARFGEF family member 3 | 0.0161131 |
| HMGA1 | high mobility group AT-hook 1 | 0.0160917 |
| FAM107B | family with sequence similarity 107, member B | 0.0158311 |
| STC1 | stanniocalcin 1 | 0.0154385 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0154177 |
| HDGF | hepatoma-derived growth factor | 0.0152778 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0152474 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0151934 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0150929 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0146734 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0146543 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0146529 |
| FOCAD | focadhesin | 0.0145613 |
| EMP1 | epithelial membrane protein 1 | 0.0144202 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0143189 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0141907 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0141801 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0141782 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0140776 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0140296 |
| HOMER2 | homer scaffolding protein 2 | 0.0140278 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.300808 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.194622 |
| EXT1 | exostosin glycosyltransferase 1 | -0.183467 |
| VCL | vinculin | -0.128062 |
| SQSTM1 | sequestosome 1 | -0.110853 |
| CANX | calnexin | -0.0862551 |
| TMSB10 | thymosin beta 10 | -0.0763263 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0697128 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0600842 |
| FNDC3B | fibronectin type III domain containing 3B | -0.05786 |
| ASPH | aspartate beta-hydroxylase | -0.0575371 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0545973 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0541249 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0532797 |
| ITGA1 | integrin, alpha 1 | -0.0527355 |
| SYT1 | synaptotagmin I | -0.0526981 |
| NTN4 | netrin 4 | -0.0522682 |
| RAB31 | RAB31, member RAS oncogene family | -0.0521919 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0504274 |
| MT2A | metallothionein 2A | -0.0496918 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0475414 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0461857 |
| OSMR | oncostatin M receptor | -0.0455295 |
| ETNK1 | ethanolamine kinase 1 | -0.0451799 |
| PTMA | prothymosin, alpha | -0.0448199 |
| OGA | O-GlcNAcase | -0.0447479 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0446877 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.044293 |
| MAP1B | microtubule-associated protein 1B | -0.0442035 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0441799 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0431102 |
| HDLBP | high density lipoprotein binding protein | -0.0425363 |
| RBM39 | RNA binding motif protein 39 | -0.0424124 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0423439 |
| TOP1 | topoisomerase (DNA) I | -0.041701 |
| GLIS3 | GLIS family zinc finger 3 | -0.0411627 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0397882 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0395283 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0382181 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0380575 |
| RRBP1 | ribosome binding protein 1 | -0.0379321 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0377072 |
| AHR | aryl hydrocarbon receptor | -0.037439 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0368788 |
| ETV6 | ets variant 6 | -0.0368588 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0368293 |
| VMP1 | vacuole membrane protein 1 | -0.036786 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0367716 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0365384 |
| FNBP1 | formin binding protein 1 | -0.0361047 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0357514 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0354836 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.035145 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0351329 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0347264 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0346488 |
| FTL | ferritin, light polypeptide | -0.0345562 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0344381 |
| SMOX | spermine oxidase | -0.0341333 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0340328 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.034006 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0333366 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0331187 |
| JMJD1C | jumonji domain containing 1C | -0.0330587 |
| MYO10 | myosin X | -0.032999 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0329929 |
| GOLGB1 | golgin B1 | -0.0322902 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0322711 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0320356 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0317571 |
| SMYD3 | SET and MYND domain containing 3 | -0.031593 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0309831 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0308542 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.030812 |
| AEBP2 | AE binding protein 2 | -0.0308078 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0301487 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0300272 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0299396 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0298787 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0297305 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0296639 |
| CD44 | CD44 molecule (Indian blood group) | -0.0294462 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.029252 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0292473 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0291945 |
| TMSB4X | thymosin beta 4, X-linked | -0.0287741 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0286972 |
| ZNF644 | zinc finger protein 644 | -0.0284009 |
| HPCAL1 | hippocalcin-like 1 | -0.0280909 |
| EREG | epiregulin | -0.0277025 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0275016 |
| SP100 | SP100 nuclear antigen | -0.0271812 |
| PALLD | palladin, cytoskeletal associated protein | -0.0270035 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0267845 |
| GNAS | GNAS complex locus | -0.0266716 |
| NEK7 | NIMA-related kinase 7 | -0.0266262 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0263548 |
| RPS24 | ribosomal protein S24 | -0.0262621 |
| FOXP1 | forkhead box P1 | -0.0261842 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0260401 |
