| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.152364 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.137588 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.130094 |
| PGK1 | phosphoglycerate kinase 1 | 0.116028 |
| LDHA | lactate dehydrogenase A | 0.0992667 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0884611 |
| FAT1 | FAT atypical cadherin 1 | 0.0791921 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0717845 |
| PKM | pyruvate kinase, muscle | 0.0700739 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0664172 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0573638 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0567292 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0553933 |
| KRT19 | keratin 19, type I | 0.0544559 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0537621 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0496351 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0463112 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0453446 |
| B2M | beta-2-microglobulin | 0.0439914 |
| CCNL1 | cyclin L1 | 0.0434842 |
| RNF43 | ring finger protein 43 | 0.0431358 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0420817 |
| RPL35A | ribosomal protein L35a | 0.0407887 |
| RPL13A | ribosomal protein L13a | 0.0391778 |
| RPS6 | ribosomal protein S6 | 0.0389463 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0374748 |
| RAD51B | RAD51 paralog B | 0.037115 |
| ACTG1 | actin gamma 1 | 0.0362219 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0341161 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.033864 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0332159 |
| MKRN1 | makorin ring finger protein 1 | 0.0331737 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0324736 |
| CTSA | cathepsin A | 0.0314148 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0311891 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0311587 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0308118 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0302426 |
| RPLP0 | ribosomal protein, large, P0 | 0.029913 |
| MUC13 | mucin 13, cell surface associated | 0.0292628 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.029252 |
| RPS2 | ribosomal protein S2 | 0.0287484 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0270746 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0270139 |
| ADM | adrenomedullin | 0.026974 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0263721 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0261586 |
| KRT18 | keratin 18, type I | 0.0254848 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0254216 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0247639 |
| UBXN4 | UBX domain protein 4 | 0.0247617 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | 0.0243047 |
| LOC112694756 | uncharaterized LOC112694756 | 0.024201 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0240895 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0240332 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.0239483 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0239225 |
| NONO | non-POU domain containing, octamer-binding | 0.0236874 |
| NDRG1 | N-myc downstream regulated 1 | 0.0235585 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0234635 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0233785 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0232886 |
| RPL27 | ribosomal protein L27 | 0.023189 |
| TXNIP | thioredoxin interacting protein | 0.0231287 |
| ANXA4 | annexin A4 | 0.0227849 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0227016 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0226768 |
| DNM2 | dynamin 2 | 0.0226063 |
| SBF2 | SET binding factor 2 | 0.0223969 |
| FNBP4 | formin binding protein 4 | 0.0218612 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.021849 |
| RPS26 | ribosomal protein S26 | 0.0216063 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0215733 |
| PKP4 | plakophilin 4 | 0.0215328 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0212515 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0212416 |
| PTCH1 | patched 1 | 0.021194 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0211285 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0211074 |
| RPS13 | ribosomal protein S13 | 0.021045 |
| GANAB | glucosidase, alpha; neutral AB | 0.0208949 |
| LRRC58 | leucine rich repeat containing 58 | 0.0208702 |
| RPS25 | ribosomal protein S25 | 0.0207755 |
| ATP9A | ATPase, class II, type 9A | 0.0204371 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0203115 |
| RPL30 | ribosomal protein L30 | 0.0202933 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.020233 |
| USP34 | ubiquitin specific peptidase 34 | 0.0201036 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0200806 |
| RBM33 | RNA binding motif protein 33 | 0.019908 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0198949 |
| NBAS | neuroblastoma amplified sequence | 0.0197378 |
| SFTPA2 | surfactant protein A2 | 0.0196848 |
| XYLT1 | xylosyltransferase I | 0.0196758 |
| RPS14 | ribosomal protein S14 | 0.0196466 |
| ENO1 | enolase 1, (alpha) | 0.0196198 |
| PCBP1 | poly(rC) binding protein 1 | 0.0195188 |
| ZFHX3 | zinc finger homeobox 3 | 0.0194682 |
| RPS27 | ribosomal protein S27 | 0.0193732 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0193514 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.128684 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.122293 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.088364 |
| TMSB10 | thymosin beta 10 | -0.085989 |
| FTL | ferritin, light polypeptide | -0.0792931 |
| RBM39 | RNA binding motif protein 39 | -0.0723961 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0670334 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0596703 |
| EZR | ezrin | -0.0572205 |
| VCL | vinculin | -0.0559494 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0543498 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0536141 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0513159 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0505519 |
| AHNAK | AHNAK nucleoprotein | -0.0469672 |
| SPAG9 | sperm associated antigen 9 | -0.0444571 |
| NAV2 | neuron navigator 2 | -0.0428153 |
| EPCAM | epithelial cell adhesion molecule | -0.0414827 |
| VMP1 | vacuole membrane protein 1 | -0.040384 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0402704 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0397314 |
| CENPF | centromere protein F, 350/400kDa | -0.0393442 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0388473 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0387478 |
| PERP | PERP, TP53 apoptosis effector | -0.038299 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0376177 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0371684 |
| TES | testin LIM domain protein | -0.036577 |
| MKI67 | marker of proliferation Ki-67 | -0.0362398 |
| OXSR1 | oxidative stress responsive 1 | -0.0362338 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0360142 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0358902 |
| KRT8 | keratin 8, type II | -0.0351659 |
| SNX9 | sorting nexin 9 | -0.0351491 |
| AFDN | afadin, adherens junction formation factor | -0.0350064 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0349939 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0347888 |
| RPL32 | ribosomal protein L32 | -0.0346363 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0346184 |
| TMSB4X | thymosin beta 4, X-linked | -0.0345787 |
| RHEB | Ras homolog enriched in brain | -0.0342632 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0341793 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0341791 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0340509 |
| TPX2 | TPX2, microtubule-associated | -0.0333957 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0331758 |
| ECT2 | epithelial cell transforming 2 | -0.0327431 |
| H1-0 | H1.0 linker histone | -0.0325981 |
| ACTN4 | actinin, alpha 4 | -0.0318544 |
| GNAS | GNAS complex locus | -0.0317088 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0312177 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0310579 |
| IER3 | immediate early response 3 | -0.0310177 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0308382 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0308014 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0305591 |
| JMJD1C | jumonji domain containing 1C | -0.0302755 |
| RYBP | RING1 and YY1 binding protein | -0.0299029 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0298453 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0298158 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0296038 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.029527 |
| CENPE | centromere protein E, 312kDa | -0.0293188 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0291226 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0287265 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0286934 |
| MATR3 | matrin 3 | -0.0283251 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0282746 |
| ZNF292 | zinc finger protein 292 | -0.0282257 |
| TJP1 | tight junction protein 1 | -0.0281945 |
| LMNA | lamin A/C | -0.0281664 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0280529 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0272607 |
| UBC | ubiquitin C | -0.0270663 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0269826 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0266937 |
| FRMD5 | FERM domain containing 5 | -0.026436 |
| TFG | TRK-fused gene | -0.0259332 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0257652 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0254432 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0251312 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0248271 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0243024 |
| SMAD2 | SMAD family member 2 | -0.0242042 |
| TOP1 | topoisomerase (DNA) I | -0.0236491 |
| LMO7 | LIM domain 7 | -0.0232991 |
| MEF2A | myocyte enhancer factor 2A | -0.0232885 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0231325 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0229419 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0226446 |
| FHL2 | four and a half LIM domains 2 | -0.0225146 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0223304 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0223237 |
| TUFT1 | tuftelin 1 | -0.022197 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.022071 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0220465 |
| USP15 | ubiquitin specific peptidase 15 | -0.0218612 |
| MYO1E | myosin IE | -0.0218391 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0216038 |
| PRPF4B | pre-mRNA processing factor 4B | -0.0212461 |
