| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.112066 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.103896 |
| ACTG1 | actin gamma 1 | 0.10322 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.102133 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0954353 |
| FAT1 | FAT atypical cadherin 1 | 0.092229 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0916738 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0889736 |
| NDRG1 | N-myc downstream regulated 1 | 0.081691 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0808202 |
| RNF43 | ring finger protein 43 | 0.0786465 |
| EGR1 | early growth response 1 | 0.0727583 |
| LAMC2 | laminin, gamma 2 | 0.0646127 |
| ATXN1 | ataxin 1 | 0.0627494 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0554299 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0546725 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0530833 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0512597 |
| AREG | amphiregulin | 0.0511184 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.0474602 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0469923 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0454535 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0436908 |
| CTSB | cathepsin B | 0.0435531 |
| EPHA2 | EPH receptor A2 | 0.0431011 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.043096 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0422488 |
| TGFB2 | transforming growth factor, beta 2 | 0.0405283 |
| AXIN2 | axin 2 | 0.0405247 |
| FLNA | filamin A, alpha | 0.0404981 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0404117 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.040195 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0398123 |
| OXR1 | oxidation resistance 1 | 0.0376694 |
| RUNX2 | runt-related transcription factor 2 | 0.0372527 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0359352 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0351386 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.035055 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0348711 |
| KLK10 | kallikrein-related peptidase 10 | 0.0339988 |
| FOSL1 | FOS-like antigen 1 | 0.0339138 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0335639 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0324764 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0321466 |
| BCL2L1 | BCL2-like 1 | 0.0309399 |
| USP6NL | USP6 N-terminal like | 0.0301497 |
| EMP1 | epithelial membrane protein 1 | 0.030148 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0289142 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0288398 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0284968 |
| HMGA1 | high mobility group AT-hook 1 | 0.0282734 |
| EDAR | ectodysplasin A receptor | 0.0282636 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0280708 |
| LMO7 | LIM domain 7 | 0.0276495 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0274645 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0274182 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0264818 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0262562 |
| CD9 | CD9 molecule | 0.0261741 |
| PGK1 | phosphoglycerate kinase 1 | 0.0259468 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0258999 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0258975 |
| YAP1 | Yes-associated protein 1 | 0.0255752 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0254977 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0253596 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.025275 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0248898 |
| ACTN4 | actinin, alpha 4 | 0.0246528 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0245799 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0244647 |
| ANXA3 | annexin A3 | 0.0244645 |
| ARFGEF3 | ARFGEF family member 3 | 0.0241317 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0241111 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0240029 |
| BMP4 | bone morphogenetic protein 4 | 0.0239772 |
| PKM | pyruvate kinase, muscle | 0.0239064 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0235991 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0233594 |
| PFKP | phosphofructokinase, platelet | 0.0233385 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0227766 |
| EGFR | epidermal growth factor receptor | 0.0227318 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.022657 |
| TXNIP | thioredoxin interacting protein | 0.0226352 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0223135 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0218401 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0216995 |
| MT2A | metallothionein 2A | 0.0216508 |
| CDCP1 | CUB domain containing protein 1 | 0.0215888 |
| ZNRF3 | zinc and ring finger 3 | 0.0215833 |
| TMEM41B | transmembrane protein 41B | 0.0215667 |
| RANBP9 | RAN binding protein 9 | 0.0212969 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0211981 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0211978 |
| EXOC6B | exocyst complex component 6B | 0.021142 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0209969 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0208724 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0207926 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0204696 |
| YEATS2 | YEATS domain containing 2 | 0.0203337 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0200376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.299645 |
| IER3 | immediate early response 3 | -0.142305 |
| TMSB10 | thymosin beta 10 | -0.139194 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.120694 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112572 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.109977 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0808696 |
| VCL | vinculin | -0.0788732 |
| RPS24 | ribosomal protein S24 | -0.0667236 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0539484 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0536102 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0491713 |
| MTAP | methylthioadenosine phosphorylase | -0.0491668 |
| FERMT1 | fermitin family member 1 | -0.0441096 |
| RPL31 | ribosomal protein L31 | -0.0438119 |
| S100A10 | S100 calcium binding protein A10 | -0.0437706 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0402149 |
| RPL5 | ribosomal protein L5 | -0.0400974 |
| RCOR1 | REST corepressor 1 | -0.0399083 |
| RPS8 | ribosomal protein S8 | -0.039906 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0397849 |
| DSPP | dentin sialophosphoprotein | -0.0396171 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0385799 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0385502 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0384315 |
| RPL34 | ribosomal protein L34 | -0.0380243 |
| RPS3 | ribosomal protein S3 | -0.0372165 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0367958 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0364922 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0360336 |
| LAMA4 | laminin, alpha 4 | -0.0358802 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0357702 |
| SQSTM1 | sequestosome 1 | -0.0350772 |
| YBX1 | Y box binding protein 1 | -0.035043 |
| RPL26 | ribosomal protein L26 | -0.0335032 |
| RPL19 | ribosomal protein L19 | -0.0332426 |
| RPL32 | ribosomal protein L32 | -0.0331069 |
| RPS12 | ribosomal protein S12 | -0.0325304 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0320801 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0316857 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0313538 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0311587 |
| ANXA1 | annexin A1 | -0.0308438 |
| LAMB3 | laminin, beta 3 | -0.02994 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0292341 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0290662 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0290169 |
| FHIT | fragile histidine triad | -0.0289554 |
| CBX3 | chromobox homolog 3 | -0.0288912 |
| RPL12 | ribosomal protein L12 | -0.0288397 |
| RPS17 | ribosomal protein S17 | -0.0288062 |
| RPLP2 | ribosomal protein, large, P2 | -0.0282692 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.027653 |
| KRT18 | keratin 18, type I | -0.0272428 |
| RBM25 | RNA binding motif protein 25 | -0.0270408 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0264233 |
| RPL23 | ribosomal protein L23 | -0.0263054 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0263029 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0262054 |
| CENPF | centromere protein F, 350/400kDa | -0.0259015 |
| ABR | active BCR-related | -0.025495 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0251068 |
| RPS6 | ribosomal protein S6 | -0.0249407 |
| RPS5 | ribosomal protein S5 | -0.024801 |
| RPS27A | ribosomal protein S27a | -0.0246508 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0240953 |
| FTL | ferritin, light polypeptide | -0.0240727 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0239828 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0234957 |
| RBM39 | RNA binding motif protein 39 | -0.0230653 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.023043 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0229691 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0229243 |
| RPS23 | ribosomal protein S23 | -0.0227403 |
| TUBB | tubulin, beta class I | -0.022728 |
| RPS19 | ribosomal protein S19 | -0.022711 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0227021 |
| RPL37A | ribosomal protein L37a | -0.0226606 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.0226348 |
| GPHN | gephyrin | -0.0224801 |
| RPL14 | ribosomal protein L14 | -0.0224398 |
| HMGB1 | high mobility group box 1 | -0.0222049 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0217471 |
| COG5 | component of oligomeric golgi complex 5 | -0.0214905 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0207898 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0205629 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0204913 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.020484 |
| MATR3 | matrin 3 | -0.0202313 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0202177 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0201902 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0201339 |
| RPL7A | ribosomal protein L7a | -0.0200715 |
| RBM26 | RNA binding motif protein 26 | -0.0200646 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0199984 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0198927 |
| SET | SET nuclear proto-oncogene | -0.0196332 |
| DEK | DEK proto-oncogene | -0.0196141 |
| ASPH | aspartate beta-hydroxylase | -0.0195987 |
| SETD5 | SET domain containing 5 | -0.0195915 |
