| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Medroxyprogesterone acetate_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.193457 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.151137 |
| LDHA | lactate dehydrogenase A | 0.140902 |
| PGK1 | phosphoglycerate kinase 1 | 0.137897 |
| PKM | pyruvate kinase, muscle | 0.0788075 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0771788 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.068577 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0674364 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0666335 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0662164 |
| ENO1 | enolase 1, (alpha) | 0.0488536 |
| ITGB4 | integrin, beta 4 | 0.0448056 |
| HMGA1 | high mobility group AT-hook 1 | 0.0432163 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0427691 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0399979 |
| TXNIP | thioredoxin interacting protein | 0.0394623 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0379338 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0364129 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0355637 |
| NONO | non-POU domain containing, octamer-binding | 0.0345863 |
| KIZ | kizuna centrosomal protein | 0.0345087 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0340681 |
| RPS6 | ribosomal protein S6 | 0.0339043 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0337254 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0331514 |
| RPS2 | ribosomal protein S2 | 0.0326899 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0316902 |
| RPLP0 | ribosomal protein, large, P0 | 0.0306947 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0303122 |
| TGM2 | transglutaminase 2 | 0.0291877 |
| LOC112694756 | uncharaterized LOC112694756 | 0.028426 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0273037 |
| CDCP1 | CUB domain containing protein 1 | 0.0271734 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0267792 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.025985 |
| CCNL1 | cyclin L1 | 0.0256118 |
| RNF43 | ring finger protein 43 | 0.0254976 |
| PROX1 | prospero homeobox 1 | 0.0248742 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0246437 |
| TNS4 | tensin 4 | 0.0245669 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0240974 |
| NDRG1 | N-myc downstream regulated 1 | 0.0237704 |
| CTSB | cathepsin B | 0.023634 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0232881 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0232004 |
| ANXA4 | annexin A4 | 0.0229404 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0227967 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0221584 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0217719 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0217108 |
| FOSL2 | FOS-like antigen 2 | 0.0215603 |
| RPL13A | ribosomal protein L13a | 0.0209147 |
| AOPEP | aminopeptidase O (putative) | 0.0208282 |
| RPL39 | ribosomal protein L39 | 0.020755 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0206049 |
| IGF2 | insulin-like growth factor 2 | 0.0206015 |
| LDHB | lactate dehydrogenase B | 0.0204939 |
| EGR1 | early growth response 1 | 0.020338 |
| AXIN2 | axin 2 | 0.0200655 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0199468 |
| B2M | beta-2-microglobulin | 0.0197096 |
| MSN | moesin | 0.0196692 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0195818 |
| KRT19 | keratin 19, type I | 0.0194743 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0193122 |
| PLEC | plectin | 0.0192253 |
| POTEF | POTE ankyrin domain family, member F | 0.0189013 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0188902 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0184577 |
| NUP58 | nucleoporin 58 | 0.0181777 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0181529 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0181324 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0181012 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0180603 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0180197 |
| RREB1 | ras responsive element binding protein 1 | 0.0176898 |
| FLNA | filamin A, alpha | 0.0172534 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0171627 |
| PTCH1 | patched 1 | 0.0170867 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0170468 |
| SFTPA2 | surfactant protein A2 | 0.0167378 |
| TUBA1B | tubulin, alpha 1b | 0.0166734 |
| LRRC58 | leucine rich repeat containing 58 | 0.0166609 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.016569 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0165341 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0164092 |
| WWOX | WW domain containing oxidoreductase | 0.0164 |
| GANAB | glucosidase, alpha; neutral AB | 0.0163262 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.0161828 |
| TMEM47 | transmembrane protein 47 | 0.016055 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0159552 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0156613 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 0.0156374 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0155009 |
| ITSN2 | intersectin 2 | 0.0154934 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0154482 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.0152841 |
| ZNRF3 | zinc and ring finger 3 | 0.0152351 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.0152119 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0150257 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.13847 |
| TMSB10 | thymosin beta 10 | -0.135078 |
| INTS6 | integrator complex subunit 6 | -0.089651 |
| LMO7 | LIM domain 7 | -0.0819844 |
| PTMA | prothymosin, alpha | -0.0674285 |
| RBM39 | RNA binding motif protein 39 | -0.0652038 |
| EZR | ezrin | -0.0635358 |
| RPS24 | ribosomal protein S24 | -0.0601637 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0567032 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0544293 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0526513 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0526071 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0518398 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0508828 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0503551 |
| CDK6 | cyclin-dependent kinase 6 | -0.0495526 |
| SYT1 | synaptotagmin I | -0.0490255 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0476166 |
| CDH13 | cadherin 13 | -0.0471665 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0460728 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0460638 |
| NF1 | neurofibromin 1 | -0.0459094 |
| THOC2 | THO complex 2 | -0.0449028 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0445887 |
| MED13 | mediator complex subunit 13 | -0.0442 |
| ETNK1 | ethanolamine kinase 1 | -0.0441889 |
| DST | dystonin | -0.0440398 |
| TMSB4X | thymosin beta 4, X-linked | -0.0436812 |
| KRT8 | keratin 8, type II | -0.0435775 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.043278 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.041564 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0414991 |
| AHNAK | AHNAK nucleoprotein | -0.0411743 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0409687 |
| ANKRD11 | ankyrin repeat domain 11 | -0.040771 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0405843 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0402889 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0395651 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0391272 |
| RPL32 | ribosomal protein L32 | -0.0389829 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0387228 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0380134 |
| SPATA13 | spermatogenesis associated 13 | -0.0373247 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0373109 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0371503 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.03692 |
| TBC1D22A | TBC1 domain family, member 22A | -0.036874 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0366606 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0365064 |
| TOP1 | topoisomerase (DNA) I | -0.0361907 |
| PERP | PERP, TP53 apoptosis effector | -0.0360089 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0355444 |
| JMJD1C | jumonji domain containing 1C | -0.0354533 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0354229 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0352533 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0352326 |
| MAP4 | microtubule-associated protein 4 | -0.035209 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0351325 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.034668 |
| UTRN | utrophin | -0.0344913 |
| RPS21 | ribosomal protein S21 | -0.0342423 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.034133 |
| S100A10 | S100 calcium binding protein A10 | -0.03291 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0328881 |
| VMP1 | vacuole membrane protein 1 | -0.0327756 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0326257 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0321705 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0320888 |
| IER3 | immediate early response 3 | -0.031973 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0308945 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0307879 |
| GOLGB1 | golgin B1 | -0.0306204 |
| CDK13 | cyclin-dependent kinase 13 | -0.0305998 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0305347 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0304663 |
| POU2F1 | POU class 2 homeobox 1 | -0.0303488 |
| CANX | calnexin | -0.0303152 |
| MORF4L2 | mortality factor 4 like 2 | -0.0302924 |
| DIAPH3 | diaphanous-related formin 3 | -0.0301937 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0299106 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0298152 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0294524 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0294349 |
| HDLBP | high density lipoprotein binding protein | -0.0293522 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.029274 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0289056 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0287938 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0287633 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.028532 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0283666 |
| STK24 | serine/threonine kinase 24 | -0.0283587 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.02823 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0281676 |
| OGA | O-GlcNAcase | -0.0281436 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0281371 |
| ACTN4 | actinin, alpha 4 | -0.0279302 |
| GOLGA4 | golgin A4 | -0.0279197 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0278743 |
| RPL26 | ribosomal protein L26 | -0.0276125 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0274423 |
