| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Medroxyprogesterone acetate perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Medroxyprogesterone acetate_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.469397 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.160545 |
| COL6A3 | collagen, type VI, alpha 3 | 0.140046 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.12263 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.104188 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.100891 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.100399 |
| HMGA2 | high mobility group AT-hook 2 | 0.0930828 |
| MYO10 | myosin X | 0.0812676 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0759968 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0744979 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0663798 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0626252 |
| NAV1 | neuron navigator 1 | 0.0505784 |
| GLIS3 | GLIS family zinc finger 3 | 0.0503704 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0495494 |
| LOXL2 | lysyl oxidase-like 2 | 0.0466324 |
| EGFR | epidermal growth factor receptor | 0.045668 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0450471 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0447219 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0429082 |
| CD44 | CD44 molecule (Indian blood group) | 0.0416842 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0388218 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0383301 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0374637 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0372936 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0365443 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0361174 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.03565 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.035025 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0341457 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0340677 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.033609 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0330662 |
| LOX | lysyl oxidase | 0.0307405 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0278493 |
| ASPH | aspartate beta-hydroxylase | 0.0277471 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0271011 |
| LDHA | lactate dehydrogenase A | 0.0264611 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0262911 |
| ACTG1 | actin gamma 1 | 0.0256034 |
| HLA-B | major histocompatibility complex, class I, B | 0.024898 |
| MMP2 | matrix metallopeptidase 2 | 0.0248308 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0247757 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0247381 |
| FRMD4A | FERM domain containing 4A | 0.0244804 |
| PGK1 | phosphoglycerate kinase 1 | 0.0239325 |
| OXR1 | oxidation resistance 1 | 0.0238462 |
| SFTPA2 | surfactant protein A2 | 0.0237102 |
| ATP13A3 | ATPase type 13A3 | 0.0233747 |
| RAI14 | retinoic acid induced 14 | 0.0228744 |
| INHBA | inhibin, beta A | 0.0227826 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0220959 |
| COL1A1 | collagen, type I, alpha 1 | 0.0218506 |
| PRR16 | proline rich 16 | 0.0216063 |
| CDH13 | cadherin 13 | 0.0214701 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0213293 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0210822 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0210755 |
| NRP1 | neuropilin 1 | 0.020897 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0204895 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0193781 |
| CAVIN1 | caveolae associated protein 1 | 0.0192806 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0192649 |
| FRMD6 | FERM domain containing 6 | 0.0191743 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0190754 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0186035 |
| EMP1 | epithelial membrane protein 1 | 0.0182857 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0181684 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0181488 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0181359 |
| NOTCH2 | notch 2 | 0.0180985 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0179334 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0177339 |
| RUNX1 | runt-related transcription factor 1 | 0.0174279 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0174049 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0173738 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0173663 |
| EGR1 | early growth response 1 | 0.0166037 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0165826 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0164066 |
| FBN1 | fibrillin 1 | 0.0162856 |
| MYADM | myeloid-associated differentiation marker | 0.0162213 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0160785 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0158539 |
| OSMR | oncostatin M receptor | 0.015582 |
| ADAMTSL1 | ADAMTS-like 1 | 0.0155592 |
| HAS2 | hyaluronan synthase 2 | 0.0155145 |
| CLMP | CXADR-like membrane protein | 0.0153359 |
| POTEF | POTE ankyrin domain family, member F | 0.0152493 |
| PLEC | plectin | 0.0151271 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0148351 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0148008 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0147683 |
| MCL1 | myeloid cell leukemia 1 | 0.0146876 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0146376 |
| ITGA11 | integrin, alpha 11 | 0.0144574 |
| ANO6 | anoctamin 6 | 0.0143801 |
| MYO1B | myosin IB | 0.0142606 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0138405 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.174408 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.132229 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0721625 |
| FTL | ferritin, light polypeptide | -0.0630688 |
| TMSB10 | thymosin beta 10 | -0.0604186 |
| GOLGA4 | golgin A4 | -0.0543544 |
| PTMA | prothymosin, alpha | -0.0543447 |
| SPAG9 | sperm associated antigen 9 | -0.0425713 |
| MT2A | metallothionein 2A | -0.039051 |
| ADM | adrenomedullin | -0.0382877 |
| STC1 | stanniocalcin 1 | -0.0359668 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0358853 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0317469 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0297928 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0293517 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0287309 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0286731 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0280693 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0278466 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0269932 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0264819 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0252969 |
| RBM39 | RNA binding motif protein 39 | -0.0249875 |
| CALR | calreticulin | -0.0240878 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0240404 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0236415 |
| HDLBP | high density lipoprotein binding protein | -0.0236363 |
| HELZ | helicase with zinc finger | -0.0230524 |
| OGA | O-GlcNAcase | -0.0230151 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0225812 |
| USP3 | ubiquitin specific peptidase 3 | -0.0224215 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0220097 |
| MORF4L2 | mortality factor 4 like 2 | -0.0218854 |
| CALU | calumenin | -0.0218525 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0217956 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0213721 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0211123 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0210278 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0210027 |
| RPL31 | ribosomal protein L31 | -0.0207956 |
| CANX | calnexin | -0.0207761 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0205808 |
| RRBP1 | ribosome binding protein 1 | -0.0203867 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.020001 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0197868 |
| LMNA | lamin A/C | -0.0192665 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0187701 |
| PRRC2C | proline-rich coiled-coil 2C | -0.018542 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0184615 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0183696 |
| YBX3 | Y box binding protein 3 | -0.0183193 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0182482 |
| YBX1 | Y box binding protein 1 | -0.0182084 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0181041 |
| PFN1 | profilin 1 | -0.0180511 |
| RPS6 | ribosomal protein S6 | -0.0180242 |
| COPA | coatomer protein complex, subunit alpha | -0.0178691 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0176291 |
| COG5 | component of oligomeric golgi complex 5 | -0.0175255 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0174475 |
| DSCAM | Down syndrome cell adhesion molecule | -0.01734 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0171153 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0169834 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0167759 |
| PHIP | pleckstrin homology domain interacting protein | -0.0167631 |
| MMP1 | matrix metallopeptidase 1 | -0.0166439 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0165773 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0162745 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0161942 |
| NUP58 | nucleoporin 58 | -0.0159097 |
| MXI1 | MAX interactor 1, dimerization protein | -0.015765 |
| RPL26 | ribosomal protein L26 | -0.0157083 |
| RPS12 | ribosomal protein S12 | -0.0156907 |
| NBAS | neuroblastoma amplified sequence | -0.0156736 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0156706 |
| SQSTM1 | sequestosome 1 | -0.0156091 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0155863 |
| CLINT1 | clathrin interactor 1 | -0.0155116 |
| SRGN | serglycin | -0.0154929 |
| NKTR | natural killer cell triggering receptor | -0.0154898 |
| SRP54 | signal recognition particle 54kDa | -0.0154665 |
| RSF1 | remodeling and spacing factor 1 | -0.0153925 |
| RPS17 | ribosomal protein S17 | -0.0153839 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.015291 |
| NDRG1 | N-myc downstream regulated 1 | -0.015281 |
| RPS8 | ribosomal protein S8 | -0.0152727 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.015269 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0152613 |
| GNAS | GNAS complex locus | -0.0151095 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0150748 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0150699 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0149928 |
| NAV2 | neuron navigator 2 | -0.0148865 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0148517 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0148143 |
| SEC24D | SEC24 family member D | -0.0147119 |
| SUCO | SUN domain containing ossification factor | -0.01471 |
| RPL5 | ribosomal protein L5 | -0.0146993 |
| RPS3 | ribosomal protein S3 | -0.0146754 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0146447 |
