Mefenamic Acid Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis. (Chemical Entities of Biological Interest Ontology, CHEBI_6717)
External Link http://ctdbase.org/detail.go?type=chem&acc=D008528
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Genes

34 genes/proteins interacting with the chemical Mefenamic Acid from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALB albumin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
GSTA1 glutathione S-transferase alpha 1
GSTA2 glutathione S-transferase alpha 2
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IL1B interleukin 1, beta
IL6 interleukin 6
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNK4 potassium channel, two pore domain subfamily K, member 4
SELL selectin L
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC22A9 solute carrier family 22 (organic anion transporter), member 9
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
TYR tyrosinase
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
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