Megacolon Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A colonic disease that is characterized by an abnormal dilation of the colon. (Human Disease Ontology, DOID_11372)
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Genes

569 genes co-occuring with the disease Megacolon in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
EDNRB endothelin receptor type B 3.502
RET ret proto-oncogene 3.486
EDN3 endothelin 3 3.454
PHOX2B paired-like homeobox 2b 3.376
SOX10 SRY (sex determining region Y)-box 10 3.371
GDNF glial cell derived neurotrophic factor 3.17
GFRA1 GDNF family receptor alpha 1 2.988
NRTN neurturin 2.849
PSPN persephin 2.717
ZEB2 zinc finger E-box binding homeobox 2 2.705
CALB2 calbindin 2 2.7
PAX3 paired box 3 2.639
ECE1 endothelin converting enzyme 1 2.63
KIFBP kinesin family binding protein 2.522
ARTN artemin 2.51
ACHE acetylcholinesterase (Yt blood group) 2.479
GFRA2 GDNF family receptor alpha 2 2.423
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 2.398
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.377
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.35
GFRA4 GDNF family receptor alpha 4 2.349
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.348
VIP vasoactive intestinal peptide 2.343
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.267
MITF microphthalmia-associated transcription factor 2.265
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.264
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 2.253
L1CAM L1 cell adhesion molecule 2.235
KIF26A kinesin family member 26A 2.196
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.175
FOXD3 forkhead box D3 2.169
TAC1 tachykinin, precursor 1 2.157
ALB albumin 2.15
DENND3 DENN/MADD domain containing 3 2.142
TLX2 T-cell leukemia homeobox 2 2.141
SRY sex determining region Y 2.139
PROKR1 prokineticin receptor 1 2.127
HOXB5 homeobox B5 2.106
GFRA3 GDNF family receptor alpha 3 2.09
TBATA thymus, brain and testes associated 2.09
NRG3 neuregulin 3 2.082
ZNF609 zinc finger protein 609 2.08
SOX8 SRY (sex determining region Y)-box 8 2.066
TNF tumor necrosis factor 2.043
NOS1 nitric oxide synthase 1 (neuronal) 2.037
CRP C-reactive protein, pentraxin-related 2.03
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.022
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 2.019
ACTG2 actin, gamma 2, smooth muscle, enteric 2.016
NCLN nicalin 2.006
ASCL1 achaete-scute family bHLH transcription factor 1 1.99
FAM162B family with sequence similarity 162, member B 1.988
NRG1 neuregulin 1 1.977
SNAI2 snail family zinc finger 2 1.975
SHH sonic hedgehog 1.943
BACE2 beta-site APP-cleaving enzyme 2 1.942
PHOX2A paired-like homeobox 2a 1.935
NTF3 neurotrophin 3 1.933
CHAT choline O-acetyltransferase 1.933
S100B S100 calcium binding protein B 1.929
RASGEF1A RasGEF domain family, member 1A 1.923
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.912
HAND2 heart and neural crest derivatives expressed 2 1.902
SOX9 SRY (sex determining region Y)-box 9 1.893
ELAVL4 ELAV like neuron-specific RNA binding protein 4 1.889
DSCAM Down syndrome cell adhesion molecule 1.881
IL1B interleukin 1, beta 1.838
MBTPS2 membrane-bound transcription factor peptidase, site 2 1.831
EDN2 endothelin 2 1.826
IL6 interleukin 6 1.815
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.806
PROK1 prokineticin 1 1.805
BMP4 bone morphogenetic protein 4 1.802
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 1.8
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.798
IFNG interferon, gamma 1.798
IL10 interleukin 10 1.795
ENO2 enolase 2 (gamma, neuronal) 1.794
AEBP2 AE binding protein 2 1.787
EDN1 endothelin 1 1.784
KITLG KIT ligand 1.782
NES nestin 1.773
MLN motilin 1.762
PROKR2 prokineticin receptor 2 1.762
CD4 CD4 molecule 1.761
FABP7 fatty acid binding protein 7, brain 1.751
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.747
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.729
EDNRA endothelin receptor type A 1.725
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 1.725
TH tyrosine hydroxylase 1.717
MSX1 msh homeobox 1 1.713
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 1.711
TGFB1 transforming growth factor, beta 1 1.697
ECE2 endothelin converting enzyme 2 1.695
UBR4 ubiquitin protein ligase E3 component n-recognin 4 1.693
FN1 fibronectin 1 1.678
SOX2 SRY (sex determining region Y)-box 2 1.677
SYP synaptophysin 1.675
ZIC1 Zic family member 1 1.674
NOG noggin 1.673
TYR tyrosinase 1.666
DCT dopachrome tautomerase 1.66
CDC42 cell division cycle 42 1.659
GFAP glial fibrillary acidic protein 1.658
SST somatostatin 1.65
CD8A CD8a molecule 1.649
ELP1 elongator acetyltransferase complex subunit 1 1.647
PTCH1 patched 1 1.642
IHH indian hedgehog 1.64
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.626
NGFR nerve growth factor receptor 1.62
GLI3 GLI family zinc finger 3 1.619
GTDC1 glycosyltransferase-like domain containing 1 1.619
ACTB actin, beta 1.619
NPY neuropeptide Y 1.619
CCK cholecystokinin 1.614
NGF nerve growth factor (beta polypeptide) 1.613
EGF epidermal growth factor 1.611
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.608
HOXA4 homeobox A4 1.603
NKX2-1 NK2 homeobox 1 1.602
IL17A interleukin 17A 1.602
AKT3 v-akt murine thymoma viral oncogene homolog 3 1.601
CCDC66 coiled-coil domain containing 66 1.6
EGR2 early growth response 2 1.597
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 1.59
TUBB3 tubulin, beta 3 class III 1.59
WNT1 wingless-type MMTV integration site family, member 1 1.587
BMP2 bone morphogenetic protein 2 1.575
DOK6 docking protein 6 1.575
PXDN peroxidasin 1.574
PXDNL peroxidasin-like 1.573
NRSN1 neurensin 1 1.57
BDNF brain-derived neurotrophic factor 1.57
BBS10 Bardet-Biedl syndrome 10 1.568
TLR4 toll-like receptor 4 1.565
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.565
NOD2 nucleotide-binding oligomerization domain containing 2 1.564
ERBB3 erb-b2 receptor tyrosine kinase 3 1.563
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.549
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.542
MECP2 methyl CpG binding protein 2 1.541
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.541
PAX6 paired box 6 1.539
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.538
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 1.536
CHD7 chromodomain helicase DNA binding protein 7 1.531
VAMP5 vesicle-associated membrane protein 5 1.527
PLP1 proteolipid protein 1 1.527
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.525
MUC2 mucin 2, oligomeric mucus/gel-forming 1.525
GATA2 GATA binding protein 2 1.522
BBS1 Bardet-Biedl syndrome 1 1.516
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 1.509
FGF8 fibroblast growth factor 8 (androgen-induced) 1.507
TPI1 triosephosphate isomerase 1 1.507
NLGN1 neuroligin 1 1.502
DPF3 D4, zinc and double PHD fingers, family 3 1.502
GLI1 GLI family zinc finger 1 1.488
NCAM1 neural cell adhesion molecule 1 1.484
GAP43 growth associated protein 43 1.483
IL22 interleukin 22 1.471
STMN2 stathmin 2 1.471
PHACTR4 phosphatase and actin regulator 4 1.469
RARB retinoic acid receptor, beta 1.468
EGFR epidermal growth factor receptor 1.464
GLI2 GLI family zinc finger 2 1.462
COL6A2 collagen, type VI, alpha 2 1.458
FOXF1 forkhead box F1 1.454
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.453
BBS12 Bardet-Biedl syndrome 12 1.453
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.448
LTF lactotransferrin 1.445
ALK anaplastic lymphoma receptor tyrosine kinase 1.443
GRB2 growth factor receptor-bound protein 2 1.443
BBS7 Bardet-Biedl syndrome 7 1.442
TP53 tumor protein p53 1.442
CXCL8 chemokine (C-X-C motif) ligand 8 1.441
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.439
TLR2 toll-like receptor 2 1.438
FGF4 fibroblast growth factor 4 1.437
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 1.432
CALB1 calbindin 1, 28kDa 1.431
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.427
RHOA ras homolog family member A 1.427
SLIT2 slit homolog 2 (Drosophila) 1.421
NRXN1 neurexin 1 1.419
MEN1 multiple endocrine neoplasia I 1.419
TACR1 tachykinin receptor 1 1.415
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.415
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 1.409
NOSIP nitric oxide synthase interacting protein 1.408
FGF2 fibroblast growth factor 2 (basic) 1.408
FGF10 fibroblast growth factor 10 1.404
TYRP1 tyrosinase-related protein 1 1.401
GJA1 gap junction protein, alpha 1, 43kDa 1.4
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 1.4
GCG glucagon 1.399
NF1 neurofibromin 1 1.398
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 1.395
BTBD8 BTB (POZ) domain containing 8 1.395
MEIS3 Meis homeobox 3 1.392
IL4 interleukin 4 1.391
MYH14 myosin, heavy chain 14, non-muscle 1.389
INS insulin 1.389
BBS4 Bardet-Biedl syndrome 4 1.388
BBS5 Bardet-Biedl syndrome 5 1.384
FGF7 fibroblast growth factor 7 1.381
GAL galanin/GMAP prepropeptide 1.378
LMLN leishmanolysin-like (metallopeptidase M8 family) 1.378
WNT3A wingless-type MMTV integration site family, member 3A 1.371
MYH11 myosin, heavy chain 11, smooth muscle 1.371
PTCH2 patched 2 1.368
FGF17 fibroblast growth factor 17 1.366
FAT3 FAT atypical cadherin 3 1.363
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.361
IL2 interleukin 2 1.358
OCLN occludin 1.355
PAX7 paired box 7 1.352
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 1.352
GJB2 gap junction protein, beta 2, 26kDa 1.35
ANO1 anoctamin 1, calcium activated chloride channel 1.35
SLIT3 slit homolog 3 (Drosophila) 1.348
FZD3 frizzled class receptor 3 1.347
SOX3 SRY (sex determining region Y)-box 3 1.346
APP amyloid beta (A4) precursor protein 1.34
FGF9 fibroblast growth factor 9 1.34
FGF3 fibroblast growth factor 3 1.338
KIF5B kinesin family member 5B 1.338
DLX5 distal-less homeobox 5 1.337
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 1.335
FGF20 fibroblast growth factor 20 1.335
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 1.334
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.332
FGF18 fibroblast growth factor 18 1.33
IL18 interleukin 18 1.328
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.326
NRG2 neuregulin 2 1.323
PTEN phosphatase and tensin homolog 1.322
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 1.321
TJP1 tight junction protein 1 1.32
FGF22 fibroblast growth factor 22 1.319
IL1A interleukin 1, alpha 1.319
CHGA chromogranin A 1.319
BBS2 Bardet-Biedl syndrome 2 1.315
TLR5 toll-like receptor 5 1.312
FGF16 fibroblast growth factor 16 1.31
JUN jun proto-oncogene 1.31
FOXP3 forkhead box P3 1.31
FGF6 fibroblast growth factor 6 1.31
NEUROG2 neurogenin 2 1.309
LMOD1 leiomodin 1 (smooth muscle) 1.309
FGF5 fibroblast growth factor 5 1.309
KIF1C kinesin family member 1C 1.308
SOX17 SRY (sex determining region Y)-box 17 1.308
TTC8 tetratricopeptide repeat domain 8 1.307
GJB1 gap junction protein, beta 1, 32kDa 1.307
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.307
ARHGAP15 Rho GTPase activating protein 15 1.306
MAPK3 mitogen-activated protein kinase 3 1.303
LSR lipolysis stimulated lipoprotein receptor 1.302
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.301
KIF7 kinesin family member 7 1.301
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.301
GAST gastrin 1.299
TTC7A tetratricopeptide repeat domain 7A 1.299
NXPH2 neurexophilin 2 1.298
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.297
CCDC6 coiled-coil domain containing 6 1.295
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.295
ACE angiotensin I converting enzyme 1.292
SIM2 single-minded family bHLH transcription factor 2 1.292
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 1.292
NPAS4 neuronal PAS domain protein 4 1.288
TWIST1 twist family bHLH transcription factor 1 1.288
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.287
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.287
CDH19 cadherin 19, type 2 1.286
HOXB3 homeobox B3 1.286
NR2F1 nuclear receptor subfamily 2, group F, member 1 1.282
SOX6 SRY (sex determining region Y)-box 6 1.276
NUP98 nucleoporin 98kDa 1.274
BCL2 B-cell CLL/lymphoma 2 1.273
PROK2 prokineticin 2 1.271
NCOA4 nuclear receptor coactivator 4 1.271
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.27
COL6A1 collagen, type VI, alpha 1 1.27
LMO1 LIM domain only 1 (rhombotin 1) 1.269
POU3F1 POU class 3 homeobox 1 1.266
RGS6 regulator of G-protein signaling 6 1.265
TPH1 tryptophan hydroxylase 1 1.264
NECTIN3 nectin cell adhesion molecule 3 1.263
NTS neurotensin 1.261
MNX1 motor neuron and pancreas homeobox 1 1.258
KLF4 Kruppel-like factor 4 (gut) 1.258
MYD88 myeloid differentiation primary response 88 1.257
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.256
ERBB2 erb-b2 receptor tyrosine kinase 2 1.254
SUFU suppressor of fused homolog (Drosophila) 1.254
PLAG1 pleiomorphic adenoma gene 1 1.253
ACTL6B actin-like 6B 1.251
KIF1B kinesin family member 1B 1.251
FLNA filamin A, alpha 1.25
CAVIN2 caveolae associated protein 2 1.248
BEST4 bestrophin 4 1.246
SLC35F5 solute carrier family 35, member F5 1.246
BBS9 Bardet-Biedl syndrome 9 1.245
POMC proopiomelanocortin 1.242
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.241
PGAP2 post-GPI attachment to proteins 2 1.241
MLNR motilin receptor 1.239
ZEB1 zinc finger E-box binding homeobox 1 1.237
MKS1 Meckel syndrome, type 1 1.237
TMEM67 transmembrane protein 67 1.236
ISL1 ISL LIM homeobox 1 1.236
MYO1H myosin IH 1.236
CLDN1 claudin 1 1.233
PCDHA9 protocadherin alpha 9 1.232
FGFR1 fibroblast growth factor receptor 1 1.231
TBL1X transducin (beta)-like 1X-linked 1.229
CARTPT CART prepropeptide 1.229
SOX5 SRY (sex determining region Y)-box 5 1.226
POU3F2 POU class 3 homeobox 2 1.226
EYA1 EYA transcriptional coactivator and phosphatase 1 1.224
BACE1 beta-site APP-cleaving enzyme 1 1.223
WNT5A wingless-type MMTV integration site family, member 5A 1.221
NLRP6 NLR family, pyrin domain containing 6 1.221
FZD9 frizzled class receptor 9 1.221
ZIC2 Zic family member 2 1.219
GBX2 gastrulation brain homeobox 2 1.219
MYO5B myosin VB 1.218
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.212
FOS FBJ murine osteosarcoma viral oncogene homolog 1.21
TPH2 tryptophan hydroxylase 2 1.21
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.209
RELN reelin 1.209
ERBB4 erb-b2 receptor tyrosine kinase 4 1.209
DVL1 dishevelled segment polarity protein 1 1.208
PTH parathyroid hormone 1.207
SNAP25 synaptosomal-associated protein, 25kDa 1.205
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.204
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.203
IRF6 interferon regulatory factor 6 1.203
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 1.202
TSGA13 testis specific, 13 1.199
GFRAL GDNF family receptor alpha like 1.196
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.196
CEP290 centrosomal protein 290kDa 1.195
C17ORF107 chromosome 17 open reading frame 107 1.193
MYO5C myosin VC 1.193
MBD5 methyl-CpG binding domain protein 5 1.193
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.19
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.19
OLIG2 oligodendrocyte lineage transcription factor 2 1.189
NEUROG1 neurogenin 1 1.188
SNAI1 snail family zinc finger 1 1.187
CD34 CD34 molecule 1.185
MYLK myosin light chain kinase 1.184
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 1.184
NRXN2 neurexin 2 1.184
RABGGTB Rab geranylgeranyltransferase, beta subunit 1.183
HOXA13 homeobox A13 1.182
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.177
FRS2 fibroblast growth factor receptor substrate 2 1.175
PYY peptide YY 1.175
FZD4 frizzled class receptor 4 1.174
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 1.174
FFAR2 free fatty acid receptor 2 1.173
SGO1 shugoshin 1 1.173
CCL2 chemokine (C-C motif) ligand 2 1.171
RBM24 RNA binding motif protein 24 1.168
SOX4 SRY (sex determining region Y)-box 4 1.166
IL13 interleukin 13 1.165
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.165
SMIM18 small integral membrane protein 18 1.163
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.162
TFF3 trefoil factor 3 (intestinal) 1.161
TLX3 T-cell leukemia homeobox 3 1.161
NANOG Nanog homeobox 1.161
BMP5 bone morphogenetic protein 5 1.16
MPZL1 myelin protein zero-like 1 1.16
DLL1 delta-like 1 (Drosophila) 1.159
PAX2 paired box 2 1.158
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1.156
TMEM216 transmembrane protein 216 1.154
SMAD9 SMAD family member 9 1.154
GATA3 GATA binding protein 3 1.153
SIX1 SIX homeobox 1 1.153
FGFR2 fibroblast growth factor receptor 2 1.153
PITX2 paired-like homeodomain 2 1.15
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 1.15
CSPG4 chondroitin sulfate proteoglycan 4 1.147
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 1.147
DLX2 distal-less homeobox 2 1.144
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.143
BBIP1 BBSome interacting protein 1 1.143
IL36R interleukin 36 receptor 1.143
TBX1 T-box 1 1.141
TBX2 T-box 2 1.14
CALCB calcitonin-related polypeptide beta 1.14
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.138
ZIC3 Zic family member 3 1.138
NOD1 nucleotide-binding oligomerization domain containing 1 1.138
ZSCAN5B zinc finger and SCAN domain containing 5B 1.135
FOXG1 forkhead box G1 1.135
IL5 interleukin 5 1.134
NPHP1 nephronophthisis 1 (juvenile) 1.131
ENO3 enolase 3 (beta, muscle) 1.13
CDX2 caudal type homeobox 2 1.13
PTPRC protein tyrosine phosphatase, receptor type, C 1.13
POU4F1 POU class 4 homeobox 1 1.127
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.126
GHRL ghrelin/obestatin prepropeptide 1.124
ZNF530 zinc finger protein 530 1.124
NID1 nidogen 1 1.122
OCA2 oculocutaneous albinism II 1.122
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.118
LHX2 LIM homeobox 2 1.118
CTCF CCCTC-binding factor (zinc finger protein) 1.117
FOXF2 forkhead box F2 1.117
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.116
H3C12 H3 clustered histone 12 1.115
SALL1 spalt-like transcription factor 1 1.115
NEUROG3 neurogenin 3 1.114
GRP gastrin-releasing peptide 1.113
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.111
BCHE butyrylcholinesterase 1.111
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 1.109
RSPO1 R-spondin 1 1.109
FABP2 fatty acid binding protein 2, intestinal 1.108
OTX2 orthodenticle homeobox 2 1.107
RAG2 recombination activating gene 2 1.107
POU5F1 POU class 5 homeobox 1 1.106
GATA4 GATA binding protein 4 1.105
DCHS1 dachsous cadherin-related 1 1.105
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.105
LEF1 lymphoid enhancer-binding factor 1 1.102
IGF1 insulin-like growth factor 1 (somatomedin C) 1.102
HOXB2 homeobox B2 1.101
MRPS18B mitochondrial ribosomal protein S18B 1.101
DVL3 dishevelled segment polarity protein 3 1.1
H3-3B H3.3 histone B 1.098
LAMA5 laminin, alpha 5 1.096
F2 coagulation factor II (thrombin) 1.096
NMU neuromedin U 1.094
GLB1 galactosidase, beta 1 1.093
SOX14 SRY (sex determining region Y)-box 14 1.093
H3-4 H3.4 histone, cluster member 1.093
NLGN2 neuroligin 2 1.093
CHM choroideremia (Rab escort protein 1) 1.092
FGF13 fibroblast growth factor 13 1.091
CSF3 colony stimulating factor 3 (granulocyte) 1.091
OLIG1 oligodendrocyte transcription factor 1 1.091
CDKN2A cyclin-dependent kinase inhibitor 2A 1.09
MSX2 msh homeobox 2 1.089
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.086
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.086
H3-5 H3.5 histone 1.085
H3C13 H3 clustered histone 13 1.085
GSK3B glycogen synthase kinase 3 beta 1.084
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.084
CASR calcium-sensing receptor 1.084
SOX1 SRY (sex determining region Y)-box 1 1.083
FZD1 frizzled class receptor 1 1.082
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 1.081
ACCSL 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like 1.081
MYOCD myocardin 1.081
SLC26A3 solute carrier family 26 (anion exchanger), member 3 1.081
POTEF POTE ankyrin domain family, member F 1.08
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.077
GLYCTK glycerate kinase 1.077
NKX2-5 NK2 homeobox 5 1.076
ASIP agouti signaling protein 1.074
CDH7 cadherin 7, type 2 1.073
LRRC18 leucine rich repeat containing 18 1.073
SMTN smoothelin 1.071
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 1.07
HRAS Harvey rat sarcoma viral oncogene homolog 1.068
ADCY10 adenylate cyclase 10 (soluble) 1.067
MYO5A myosin VA (heavy chain 12, myoxin) 1.067
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.066
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 1.066
FOXA2 forkhead box A2 1.065
NTN1 netrin 1 1.064
TRIM8 tripartite motif containing 8 1.063
GJB6 gap junction protein, beta 6, 30kDa 1.063
FZD2 frizzled class receptor 2 1.062
CLCN2 chloride channel, voltage-sensitive 2 1.062
FFAR3 free fatty acid receptor 3 1.061
KIF3A kinesin family member 3A 1.06
NTN3 netrin 3 1.059
CD274 CD274 molecule 1.059
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 1.057
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 1.055
CCDC28B coiled-coil domain containing 28B 1.053
SCN10A sodium channel, voltage gated, type X alpha subunit 1.053
BARX1 BARX homeobox 1 1.052
CHRD chordin 1.052
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.05
SPDEF SAM pointed domain containing ETS transcription factor 1.049
RPGRIP1L RPGRIP1-like 1.048
HNF4A hepatocyte nuclear factor 4, alpha 1.047
CXCL12 chemokine (C-X-C motif) ligand 12 1.047
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 1.045
MPO myeloperoxidase 1.044
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 1.044
SIX5 SIX homeobox 5 1.043
CREBBP CREB binding protein 1.042
NPR3 natriuretic peptide receptor 3 1.042
LIF leukemia inhibitory factor 1.041
WNT4 wingless-type MMTV integration site family, member 4 1.04
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 1.04
NISCH nischarin 1.039
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 1.034
COMT catechol-O-methyltransferase 1.034
PECR peroxisomal trans-2-enoyl-CoA reductase 1.033
SOX13 SRY (sex determining region Y)-box 13 1.033
SOX11 SRY (sex determining region Y)-box 11 1.032
SLC45A2 solute carrier family 45, member 2 1.032
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.03
KRT76 keratin 76, type II 1.029
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 1.027
MEF2C myocyte enhancer factor 2C 1.026
B3GAT1 beta-1,3-glucuronyltransferase 1 1.025
LBX1 ladybird homeobox 1 1.024
KDR kinase insert domain receptor 1.024
ODF2 outer dense fiber of sperm tails 2 1.022
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.02
PLA2G10 phospholipase A2, group X 1.019
INMT indolethylamine N-methyltransferase 1.019
TUBA1A tubulin, alpha 1a 1.018
MYH13 myosin, heavy chain 13, skeletal muscle 1.016
CCND1 cyclin D1 1.016
CALR calreticulin 1.016
MEIS1 Meis homeobox 1 1.016
AXIN2 axin 2 1.015
SCN11A sodium channel, voltage gated, type XI alpha subunit 1.014
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.013
BARD1 BRCA1 associated RING domain 1 1.013
FOXA1 forkhead box A1 1.012
RUFY2 RUN and FYVE domain containing 2 1.012
NLGN3 neuroligin 3 1.012
ATOH1 atonal homolog 1 (Drosophila) 1.012
VCL vinculin 1.011
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 1.011
TBX3 T-box 3 1.011
PLAGL2 pleiomorphic adenoma gene-like 2 1.011
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.009
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.009
CSF1 colony stimulating factor 1 (macrophage) 1.008
ALKAL2 ALK and LTK ligand 2 1.008
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.007
GUCY2C guanylate cyclase 2C 1.007
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.007
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.005
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.003
ERVW-1 endogenous retrovirus group W, member 1 1.003
REG3G regenerating islet-derived 3 gamma 1.003
OFD1 oral-facial-digital syndrome 1 1.003
ITPKC inositol-trisphosphate 3-kinase C 1.003
HMOX2 heme oxygenase 2 1.003
SATB1 SATB homeobox 1 1.003
CALCA calcitonin-related polypeptide alpha 1.002
CXCR4 chemokine (C-X-C motif) receptor 4 1.002
HNF1B HNF1 homeobox B 1.002
SIX3 SIX homeobox 3 1.001
AUTS2 autism susceptibility candidate 2 1.001
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3 1.001