| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Megestrol perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Megestrol_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.196875 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.168098 |
| LSAMP | limbic system-associated membrane protein | 0.155631 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.123273 |
| FMN1 | formin 1 | 0.099794 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0939968 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0928488 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0890802 |
| NRG1 | neuregulin 1 | 0.0864382 |
| IGF2 | insulin-like growth factor 2 | 0.0796007 |
| TLE4 | transducin-like enhancer of split 4 | 0.0765302 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0684558 |
| PRKCA | protein kinase C, alpha | 0.0670227 |
| MEIS2 | Meis homeobox 2 | 0.062861 |
| LPIN1 | lipin 1 | 0.0610734 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0592401 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0578226 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0572194 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.055077 |
| VMP1 | vacuole membrane protein 1 | 0.0549883 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0549822 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0536324 |
| DPH6 | diphthamine biosynthesis 6 | 0.0500684 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0498405 |
| BPTF | bromodomain PHD finger transcription factor | 0.0496773 |
| KLHL13 | kelch-like family member 13 | 0.0491248 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0470228 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0467319 |
| THBS1 | thrombospondin 1 | 0.0460685 |
| NPAS2 | neuronal PAS domain protein 2 | 0.04266 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0422024 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.039991 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0399471 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0395651 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0395477 |
| PLPP1 | phospholipid phosphatase 1 | 0.0393645 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0390811 |
| RNF213 | ring finger protein 213 | 0.038599 |
| CRH | corticotropin releasing hormone | 0.0384076 |
| EGR1 | early growth response 1 | 0.037578 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0374341 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0374295 |
| STK38L | serine/threonine kinase 38 like | 0.0373027 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.037214 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0370458 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0363692 |
| RAD51B | RAD51 paralog B | 0.036068 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0360487 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0360007 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0358231 |
| ACTG1 | actin gamma 1 | 0.0356832 |
| AUTS2 | autism susceptibility candidate 2 | 0.0356434 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0349519 |
| MYO1E | myosin IE | 0.0348414 |
| MSI2 | musashi RNA-binding protein 2 | 0.0347152 |
| DST | dystonin | 0.0345369 |
| ASPH | aspartate beta-hydroxylase | 0.0344891 |
| MBTD1 | mbt domain containing 1 | 0.0343191 |
| RIGI | RNA sensor RIG-I | 0.0342489 |
| TPM1 | tropomyosin 1 (alpha) | 0.0338622 |
| DGKH | diacylglycerol kinase, eta | 0.0337469 |
| GLCCI1 | glucocorticoid induced 1 | 0.033158 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0327078 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0317621 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0312571 |
| MCL1 | myeloid cell leukemia 1 | 0.0308046 |
| ITGAV | integrin, alpha V | 0.0304581 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0304504 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.03031 |
| CUX1 | cut-like homeobox 1 | 0.0302444 |
| GOLGB1 | golgin B1 | 0.0301688 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.02997 |
| SIK2 | salt-inducible kinase 2 | 0.029961 |
| FERMT2 | fermitin family member 2 | 0.0298665 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.029733 |
| TENM4 | teneurin transmembrane protein 4 | 0.0291339 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0290052 |
| TRIB2 | tribbles pseudokinase 2 | 0.0289675 |
| TPM4 | tropomyosin 4 | 0.0288298 |
| PLAT | plasminogen activator, tissue | 0.0286497 |
| SP100 | SP100 nuclear antigen | 0.0282452 |
| DNM3 | dynamin 3 | 0.0282097 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0280494 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0278587 |
| SEPTIN9 | septin 9 | 0.0277762 |
| FAM107B | family with sequence similarity 107, member B | 0.0274821 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0273654 |
| HOMER1 | homer scaffolding protein 1 | 0.0272473 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0271506 |
| EXOC4 | exocyst complex component 4 | 0.0271381 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0265758 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0264826 |
| ATXN1 | ataxin 1 | 0.0262833 |
| RNF150 | ring finger protein 150 | 0.0260906 |
| DACH2 | dachshund family transcription factor 2 | 0.0259633 |
| PTEN | phosphatase and tensin homolog | 0.0259313 |
| HMGA2 | high mobility group AT-hook 2 | 0.0257782 |
| SMYD3 | SET and MYND domain containing 3 | 0.0254567 |
| SETBP1 | SET binding protein 1 | 0.0251749 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0251308 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0803369 |
| PTMA | prothymosin, alpha | -0.0666758 |
| COL1A1 | collagen, type I, alpha 1 | -0.0629911 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0617976 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0476621 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0475918 |
| VIM | vimentin | -0.044911 |
| RPL19 | ribosomal protein L19 | -0.0439937 |
| RPS24 | ribosomal protein S24 | -0.0437056 |
| RPL35A | ribosomal protein L35a | -0.0436463 |
| RPLP1 | ribosomal protein, large, P1 | -0.0399032 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0369163 |
| COL3A1 | collagen, type III, alpha 1 | -0.0367031 |
| LMNA | lamin A/C | -0.0363931 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0363277 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0341246 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0337492 |
| RPL34 | ribosomal protein L34 | -0.0327062 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0314872 |
| RAD21 | RAD21 homolog (S. pombe) | -0.030403 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0285847 |
| OGA | O-GlcNAcase | -0.0284811 |
| FAM13A | family with sequence similarity 13, member A | -0.0281425 |
| RPL36A | ribosomal protein L36a | -0.0275929 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0271869 |
| FAM162A | family with sequence similarity 162, member A | -0.0269389 |
| RPL23 | ribosomal protein L23 | -0.0262227 |
| RPL38 | ribosomal protein L38 | -0.0255043 |
| TUBB | tubulin, beta class I | -0.0253381 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0252831 |
| RPL31 | ribosomal protein L31 | -0.0248038 |
| S100A6 | S100 calcium binding protein A6 | -0.024587 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0236965 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0232017 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0231181 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0226959 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0221637 |
| NUP58 | nucleoporin 58 | -0.0221526 |
| HELZ | helicase with zinc finger | -0.0220757 |
| RPS6 | ribosomal protein S6 | -0.0219919 |
| RPLP0 | ribosomal protein, large, P0 | -0.0218521 |
| CCDC47 | coiled-coil domain containing 47 | -0.0216942 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0216446 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0216164 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0215962 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0215485 |
| ARF1 | ADP-ribosylation factor 1 | -0.0215458 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0214655 |
| RPL32 | ribosomal protein L32 | -0.0214322 |
| SPAG9 | sperm associated antigen 9 | -0.0213135 |
| HMGB2 | high mobility group box 2 | -0.0210603 |
| RPS3 | ribosomal protein S3 | -0.0210481 |
| RIOK3 | RIO kinase 3 | -0.0208771 |
| RPS8 | ribosomal protein S8 | -0.0207615 |
| SUCO | SUN domain containing ossification factor | -0.0205073 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0204783 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0199506 |
| RPL27 | ribosomal protein L27 | -0.0197039 |
| OTUD7B | OTU deubiquitinase 7B | -0.0196607 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0192523 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0190414 |
| RPS27A | ribosomal protein S27a | -0.0190319 |
| RPS5 | ribosomal protein S5 | -0.018864 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0188632 |
| CALU | calumenin | -0.018853 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0186083 |
| PRR11 | proline rich 11 | -0.0185752 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0185672 |
| AHNAK | AHNAK nucleoprotein | -0.0184841 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0183887 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0183784 |
| RPS19 | ribosomal protein S19 | -0.0182642 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0182578 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0181905 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0179925 |
| CEP95 | centrosomal protein 95kDa | -0.0177593 |
| MORF4L1 | mortality factor 4 like 1 | -0.0175246 |
| NOP58 | NOP58 ribonucleoprotein | -0.0173701 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0173364 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.0172976 |
| MMP12 | matrix metallopeptidase 12 | -0.0172592 |
| RPL4 | ribosomal protein L4 | -0.0172039 |
| RPLP2 | ribosomal protein, large, P2 | -0.0171928 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0171775 |
| WDR45B | WD repeat domain 45B | -0.017138 |
| FTL | ferritin, light polypeptide | -0.0171185 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0170301 |
| FOXK2 | forkhead box K2 | -0.0168547 |
| H1-0 | H1.0 linker histone | -0.0168157 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0166676 |
| PCDH9 | protocadherin 9 | -0.0166632 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0166585 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0163475 |
| SRP72 | signal recognition particle 72kDa | -0.0162881 |
| LUM | lumican | -0.0162353 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | -0.0161531 |
| H3-3B | H3.3 histone B | -0.0161159 |
| RPS11 | ribosomal protein S11 | -0.0160863 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0160779 |
| QKI | QKI, KH domain containing, RNA binding | -0.0160557 |
