| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Megestrol perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Megestrol_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.263014 |
| LMO7 | LIM domain 7 | 0.182833 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.157921 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.126606 |
| MTSS1 | metastasis suppressor 1 | 0.118786 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.108643 |
| MT2A | metallothionein 2A | 0.0913887 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0849068 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0819418 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0804785 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0804276 |
| RASAL2 | RAS protein activator like 2 | 0.0797009 |
| HMGA2 | high mobility group AT-hook 2 | 0.079296 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0790171 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0773058 |
| SULF2 | sulfatase 2 | 0.0698984 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0658773 |
| TGM2 | transglutaminase 2 | 0.064 |
| PODXL | podocalyxin-like | 0.0629667 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0619458 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0618787 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0608895 |
| FKBP5 | FK506 binding protein 5 | 0.0606013 |
| MT1E | metallothionein 1E | 0.0596449 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0576763 |
| EFNA5 | ephrin-A5 | 0.0576299 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0569029 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0550814 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0532995 |
| RPS6 | ribosomal protein S6 | 0.0526526 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0501603 |
| CALB1 | calbindin 1, 28kDa | 0.0478429 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0471664 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0470672 |
| CDK6 | cyclin-dependent kinase 6 | 0.0467481 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0465042 |
| RNF217 | ring finger protein 217 | 0.0432747 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0432398 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0412808 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0412118 |
| SLK | STE20-like kinase | 0.0410348 |
| IFI44L | interferon-induced protein 44-like | 0.0407263 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0402703 |
| UTRN | utrophin | 0.0402243 |
| RAI14 | retinoic acid induced 14 | 0.0400011 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0391197 |
| PCDH1 | protocadherin 1 | 0.0380044 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0374422 |
| KIAA1671 | KIAA1671 | 0.0371382 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0366778 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0362459 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0357015 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0349673 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0347118 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0346348 |
| MYOF | myoferlin | 0.0344103 |
| TXNIP | thioredoxin interacting protein | 0.0339865 |
| DGKH | diacylglycerol kinase, eta | 0.0334656 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0330141 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0325641 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0324379 |
| MT1X | metallothionein 1X | 0.0321568 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0320683 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.032049 |
| JMJD1C | jumonji domain containing 1C | 0.0318115 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0316051 |
| MXRA5 | matrix-remodelling associated 5 | 0.031236 |
| PALLD | palladin, cytoskeletal associated protein | 0.0307396 |
| ITGB8 | integrin, beta 8 | 0.0306462 |
| SIK3 | SIK family kinase 3 | 0.0303987 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0302376 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0297402 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0295288 |
| PLS3 | plastin 3 | 0.0294933 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.029482 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0294285 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0292687 |
| CUX1 | cut-like homeobox 1 | 0.0292179 |
| EGFR | epidermal growth factor receptor | 0.0292023 |
| RCOR1 | REST corepressor 1 | 0.0290671 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0290115 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0287373 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0287263 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0286971 |
| PRSS23 | protease, serine, 23 | 0.0286545 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0280682 |
| KLF6 | Kruppel-like factor 6 | 0.0278942 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0277454 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0277322 |
| KRT6A | keratin 6A, type II | 0.027397 |
| EXT1 | exostosin glycosyltransferase 1 | 0.026813 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0264713 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.026433 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0263284 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0259364 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0257594 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0256682 |
| DSPP | dentin sialophosphoprotein | 0.025559 |
| PYGL | phosphorylase, glycogen, liver | 0.0254902 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.025444 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ENO1 | enolase 1, (alpha) | -0.100528 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0869187 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0746955 |
| TMSB10 | thymosin beta 10 | -0.0707658 |
| FLNB | filamin B, beta | -0.0703013 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0691067 |
| UBC | ubiquitin C | -0.0611095 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0588546 |
| KIAA1217 | KIAA1217 | -0.0567635 |
| NRG1 | neuregulin 1 | -0.0524951 |
| OGA | O-GlcNAcase | -0.0518868 |
| PTMA | prothymosin, alpha | -0.0503711 |
| LMNA | lamin A/C | -0.0490532 |
| RBM39 | RNA binding motif protein 39 | -0.0488341 |
| CANX | calnexin | -0.0474147 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0463806 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0452859 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0451261 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0448066 |
| RPS27A | ribosomal protein S27a | -0.0430588 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.042772 |
| CALU | calumenin | -0.042328 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0414194 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0411107 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0409964 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0405939 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0385876 |
| AHNAK | AHNAK nucleoprotein | -0.0377617 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.036964 |
| ANLN | anillin, actin binding protein | -0.0366662 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0355293 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0354597 |
| KRT17 | keratin 17, type I | -0.0354197 |
| STC1 | stanniocalcin 1 | -0.03498 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0346806 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0343223 |
| SERINC3 | serine incorporator 3 | -0.0341092 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0340346 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0340031 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0328517 |
| MORF4L2 | mortality factor 4 like 2 | -0.0327649 |
| RPS21 | ribosomal protein S21 | -0.0317992 |
| S100A6 | S100 calcium binding protein A6 | -0.0317312 |
| ASPH | aspartate beta-hydroxylase | -0.0310584 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0303361 |
| TMSB4X | thymosin beta 4, X-linked | -0.0303154 |
| SMAD3 | SMAD family member 3 | -0.0298572 |
| S100A2 | S100 calcium binding protein A2 | -0.0291167 |
| COPA | coatomer protein complex, subunit alpha | -0.0290827 |
| GOLGA4 | golgin A4 | -0.0289529 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0286654 |
| PCBP2 | poly(rC) binding protein 2 | -0.0286369 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0285673 |
| ANKRD10 | ankyrin repeat domain 10 | -0.028523 |
| CALR | calreticulin | -0.027961 |
| FLNA | filamin A, alpha | -0.0277285 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0276782 |
| ANXA2 | annexin A2 | -0.0270391 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.026667 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0266428 |
| SUCO | SUN domain containing ossification factor | -0.0259386 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0254533 |
| TFG | TRK-fused gene | -0.0248591 |
| SRP54 | signal recognition particle 54kDa | -0.0245859 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0242415 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0241268 |
| GATA6 | GATA binding protein 6 | -0.0237974 |
| YBX3 | Y box binding protein 3 | -0.0234389 |
| COG5 | component of oligomeric golgi complex 5 | -0.0234326 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0231971 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0231049 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0230466 |
| TPX2 | TPX2, microtubule-associated | -0.0229047 |
| B2M | beta-2-microglobulin | -0.0228115 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.022758 |
| IER3 | immediate early response 3 | -0.0226704 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0226376 |
| SDC4 | syndecan 4 | -0.0224638 |
| DSTN | destrin (actin depolymerizing factor) | -0.0224153 |
| SOX13 | SRY (sex determining region Y)-box 13 | -0.0221568 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0221266 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0221048 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.021999 |
| ITGA6 | integrin, alpha 6 | -0.0219179 |
| RPL23 | ribosomal protein L23 | -0.021834 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0217081 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0216243 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0216182 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.02152 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0214823 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.021381 |
| EMP1 | epithelial membrane protein 1 | -0.0213372 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0209652 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0208775 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0204901 |
| VMP1 | vacuole membrane protein 1 | -0.020399 |
| SPAG9 | sperm associated antigen 9 | -0.0202647 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0201703 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0198975 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0196928 |
